|1921 in Canadian football|
|East Champions||Toronto Argonauts|
|West Champions||Edmonton Eskimos|
|9th Grey Cup|
Western Canada Rugby Football Union joined the CRU and challenged for the Grey Cup. The Edmonton Eskimos became the first Western team to play in a Grey Cup game, but lost to the Toronto Argonauts 23–0.
Rule changes included reducing players from 14 to 12 per side; putting ball into play by snapping it back; limit of 18 players with substitutes permitted freely.
Note: GP = Games Played, W = Wins, L = Losses, T = Ties, PF = Points For, PA = Points Against, Pts = Points
*Bold text means that they have clinched the playoffs
|Winnipeg Tammany Tigers||4||2||2||0||53||41||4|
|University of Manitoba Varsity||4||0||4||0||53||87||0|
|Regina Rugby Club||4||4||0||0||86||11||8|
|Regina Boat Club||4||2||2||0||34||28||4|
|Moose Jaw Millers||4||0||4||0||12||93||0|
|University of Saskatchewan Varsity||3||1||2||0||18||43||2|
|University of Alberta Varsity||4||1||3||0||35||113||2|
|Calgary Rugby Club||3||1||2||0||39||104||2|
* Final game of the season was cancelled - not necessary
|Football Union||League Champion|
|CIRFU||University of Toronto|
Note: All dates in 1921
|November 4||Regina Rugby Club 6||Saskatoon 9|
|November 19||Toronto Varsity Blues 12||Toronto Argonauts 20|
|November 26||Toronto Parkdale Canoe Club 8||Toronto Argonauts 16|
|November 7||Saskatoon Quakers 1||Winnipeg Victorias 16|
|November 14||Edmonton Eskimos 16||Winnipeg Victorias 6|
|Quarter Finals||Semi Finals||Grey Cup Final|
|CIRFU||University of Toronto||12|
|Edmonton Eskimos 0||Toronto Argonauts 23|
|Toronto Argonauts are the 1921 Grey Cup Champions|
NOTE: During this time most players played both ways, so the All-Star selections do not distinguish between some offensive and defensive positions.
The Toronto Argonauts won the Grey Cup for the second time in five years.
For the second consecutive season the Toronto Argonauts and Winnipeg Blue Bombers met for the Grey Cup. The Argonauts won the game.
Football returned to relative normal in 1945 following the conclusion of World War II. Two rivals from the pre-war years met once again in the annual Grey Cup, but on this occasion, the Winnipeg Blue Bombers were no match for the Toronto Argonauts. For Winnipeg, it was the worst loss by a western team in the Grey Cup since 1923 when Queen's University routed the Regina Roughriders 54-0.
For the first time in Grey Cup history, the same two teams challenged for the trophy for the third consecutive year. But unlike the previous two years, the Toronto Argonauts needed some late game heroics to win their third consecutive title.
After a 17-year absence, the Saskatchewan Roughriders returned to the Grey Cup final. Their losing streak in the big game continued, however, as it was the other Rough Riders that took home the prize.
The Toronto Argonauts faced the Edmonton Eskimos in the Grey Cup. Although the Argos would hold on to win the game and their 10th Grey Cup championship, an Argo would not sip from the silver mug again until 1983.
The Edmonton Eskimos defeat the Montreal Alouettes in the first Grey Cup held in the west.
The Edmonton Eskimos faced the Montreal Alouettes in the Grey Cup game for the third consecutive year. And for the third consecutive year, the Edmonton Eskimos were Grey Cup champions. It was the first time in a Grey Cup that a touchdown was worth six points instead of five.
The Hamilton Tiger-Cats defeat the Winnipeg Blue Bombers in the Grey Cup.
After a four year absence due to the First World War, the Grey Cup was up for grabs once again as a couple of familiar foes battled for the trophy. The Toronto Varsity Blues defeated the Toronto Argonauts. It was the final time these cross-town rivals challenged each other for the Grey Cup.