| 2012 Open GDF Suez Nantes Atlantique | |
|---|---|
| Date | 29 October–4 November |
| Edition | 10th |
| Location | Nantes, France |
| Champions | |
| Singles | |
 Monica Niculescu | |
| Doubles | |
 Catalina Castaño /  Mervana Jugić-Salkić | |
The 2012 Open GDF Suez Nantes Atlantique was a professional tennis tournament played on indoor hard courts. It was the tenth edition of the tournament which was part of the 2012 ITF Women's Circuit. It took place in Nantes, France, on 29 October–4 November 2012.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 CZE | Petra Cetkovská | 56 | 1 |
| ROU | Monica Niculescu | 68 | 2 |
| ROU | Alexandra Cadanțu | 87 | 3 |
 FRA | Stéphanie Foretz Gacon | 101 | 4 |
 ESP | Garbiñe Muguruza | 102 | 5 |
| CZE | Kristýna Plíšková | 111 | 6 |
| CZE | Karolína Plíšková | 114 | 7 |
 AUT | Yvonne Meusburger | 115 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following player received entry by a Protected Ranking:
The following player received entry by a Junior Exempt:
The following player received entry as a Lucky loser:
Monica Niculescu def. 
Yulia Putintseva 6–2, 6–3. Catalina Castaño / Mervana Jugić-Salkić def. Petra Cetkovská / Renata Voráčová 6–4, 6–4.Iveta Benešová and Anabel Medina Garrigues were the defending champions, but decided not to participate.
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