8-hydroxyquercetin 8-O-methyltransferase

Last updated
8-hydroxyquercitin 8-O-methyltransferase
Identifiers
EC no. 2.1.1.88
CAS no. 99775-17-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, a 8-hydroxyquercetin 8-O-methyltransferase (EC 2.1.1.88) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 3,5,7,8,3',4'-hexahydroxyflavone S-adenosyl-L-homocysteine + 3,5,7,3',4'-pentahydroxy-8-methoxyflavone

Thus, the two substrates of this enzyme are S-adenosyl methionine and 3,5,7,8,3',4'-hexahydroxyflavone (gossypetin), whereas its two products are S-adenosylhomocysteine and 3,5,7,3',4'-pentahydroxy-8-methoxyflavone.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:3,5,7,8,3',4'-hexahydroxyflavone 8-O-methyltransferase. Other names in common use include flavonol 8-O-methyltransferase, flavonol 8-methyltransferase, S-adenosyl-L-methionine:3,3',4',5,7,8-hexahydroxyflavone, 8-O-methyltransferase, and 8-hydroxyquercitin 8-O-methyltransferase [mis-spelt].

Related Research Articles

In enzymology, a 3,7-dimethylquercetin 4'-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a 3-methylquercetin 7-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a caffeate O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a hexaprenyldihydroxybenzoate methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an inositol 3-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an isobutyraldoxime O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an isoflavone 4'-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a kaempferol 4'-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a luteolin O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a methylquercetagetin 6-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a myricetin O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a quercetin 3-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a (S)-scoulerine 9-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a sterigmatocystin 8-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a tabersonine 16-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a tocopherol O-methyltransferase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Gossypetin</span> Chemical compound

Gossypetin, also known as 3,5,7,8,3',4'-hexahydroxyflavone, is a flavonol, a type of flavonoid. It has been isolated from the flowers and the calyx of Hibiscus sabdariffa (roselle) and exhibits a strong antibacterial activity. The compound has also been found to act as an antagonist of TrkB. Recently it was shown that gossypetin has radioprotective activity.

<span class="mw-page-title-main">Isorhamnetin</span> Chemical compound

Isorhamnetin is an O-methylated flavon-ol from the class of flavonoids. A common food source of this 3'-methoxylated derivative of quercetin and its glucoside conjugates are pungent yellow or red onions, in which it is a minor pigment, quercetin-3,4'-diglucoside and quercetin-4'-glucoside and the aglycone quercetin being the major pigments. Pears, olive oil, wine and tomato sauce are rich in isorhamnetin. Others sources include the spice, herbal medicinal and psychoactive Mexican tarragon (Tagetes lucida), which is described as accumulating isorhamnetin and its 7-O-glucoside derivate. Nopal is also a good source of isorhamnetin, which can be extracted by supercritical fluid extraction assisted by enzymes.

<span class="mw-page-title-main">Rhamnazin</span> Chemical compound

Rhamnazin is an O-methylated flavonol, a type of chemical compound. It can be found in Rhamnus petiolaris, a buckthorn plant endemic to Sri Lanka.

8-hydroxyfuranocoumarin 8-O-methyltransferase is an enzyme with systematic name S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase. This enzyme catalyses the following chemical reaction

References


    This page is based on this Wikipedia article
    Text is available under the CC BY-SA 4.0 license; additional terms may apply.
    Images, videos and audio are available under their respective licenses.