Beta-amyrin 24-hydroxylase

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Beta-amyrin 24-hydroxylase
Identifiers
EC no. 1.14.99.43
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Beta-amyrin 24-hydroxylase (EC 1.14.99.43, sophoradiol 24-hydroxylase, CYP93E1) is an enzyme with systematic name beta-amyrin,AH2:oxygen oxidoreductase (24-hydroxylating). [1] This enzyme catalyses the following chemical reaction

(1) beta-amyrin + AH2 + O2 24-hydroxy-beta-amyrin + A + H2O
(2) sophoradiol + AH2 + O2 24-hydroxysophoradiol + A + H2O

Beta-amyrin 24-hydroxylase is heme-thiolate protein (P-450).

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References

  1. ↑ Shibuya M, Hoshino M, Katsube Y, Hayashi H, Kushiro T, Ebizuka Y (March 2006). "Identification of beta-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay". The FEBS Journal. 273 (5): 948–59. doi: 10.1111/j.1742-4658.2006.05120.x . PMID   16478469.
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