The Men's C-2 1000m event at the 2010 South American Games was held over March 27 at 10:20.
The IX South American Games was a multi-sport event held between 19–30 March 2010 in Medellín, Colombia. The Games were organized by the South American Sports Organization (ODESUR), who awarded the Games to the city with 8 votes over the bid by previous host Santiago, Chile.
| Gold | Silver | Bronze |
| Ronilson Oliveira Erlon Silva  | Eduyn Labarca Edward Luciano Paredes  | Johnnathan Francisco Quitral Fabian Antonio Valdes  |
| Rank | Athlete | Time |
|---|---|---|
 | Ronilson Oliveira Erlon Silva | 3:47.71 |
 | Eduyn Labarca Edward Luciano Paredes | 3:49.60 |
 | Johnnathan Francisco Quitral Fabian Antonio Valdes | 3:50.95 |
| 4 |  Anders Ospina Jesus Felipe Ospina | 3:56.51 |
| 5 |  Anders Felipe Arana Michael Antonio Mero | 4:12.78 |
| 6 |  Leonardo Niveiro Roberto Palacios | 4:24.04 |