Charles Nichols may refer to:
- Charles Archibald Nichols (1876–1920), politician from the U.S. state of Michigan
- Charles August Nichols (1910–1992), American animator and film director
- Kid Nichols, born Charles Augustus Nichols (1869–1953), Major League Baseball pitcher and Hall of Famer
- Charles D. Nichols, American pharmacologist and psychedelic researcher
- C. Walter Nichols, American chemist
This disambiguation page lists articles about people with the same name.
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