A chemosensitizer is a drug that makes tumor cells more sensitive to the effects of chemotherapy.
Chemotherapy is a type of cancer treatment that uses one or more anti-cancer drugs as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent, or it may aim to prolong life or to reduce symptoms. Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called medical oncology.
Acute myeloblastic leukemia without maturation is a quickly progressing disease in which too many immature white blood cells are found in the blood and bone marrow.
Adenosquamous carcinoma is a type of cancer that contains two types of cells: squamous cells and gland-like cells. It has been associated with more aggressive characteristics when compared to adenocarcinoma in certain cancers.
ALVAC-CEA vaccine is a cancer vaccine containing a canary pox virus (ALVAC) combined with the carcinoembryonic antigen (CEA) human gene.
Atamestane, also known as metandroden, as well as 1-methylandrosta-1,4-diene-3,17-dione, is a steroidal aromatase inhibitor that was studied in the treatment of cancer. It blocks the production of estrogen in the body. The drug is selective, competitive, and irreversible in its inhibition of aromatase.
Blastic phase chronic myelogenous leukemia is a phase of chronic myelogenous leukemia in which more than 30% of the cells in the blood or bone marrow are blast cells. When tiredness, fever, and an enlarged spleen occur during the blastic phase, it is called blast crisis.
Treosulfan is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called alkylating agents. It has been used mainly as a substitute of busulfan in frail patients, as the side effects and toxicity are supposedly less severe.
Collagen disease is a term previously used to describe systemic autoimmune diseases, but now is thought to be more appropriate for diseases associated with defects in collagen, which is a component of the connective tissue.
A compound nevus is a type of mole formed by groups of nevus cells found in the epidermis and dermis.
Transrectal biopsy is a biopsy procedure in which a sample of tissue is removed from the prostate using a thin needle that is inserted through the rectum and into the prostate. Transrectal ultrasound (TRUS) is usually used to guide the needle. The sample is examined under a microscope to see if it contains cancer.
Transurethral biopsy is a biopsy procedure in which a sample of tissue is removed from the prostate for examination under a microscope. A thin, lighted tube is inserted through the urethra into the prostate, and a small piece of tissue is removed with a cutting loop.
Wedge resection is a surgical procedure to remove a triangle-shaped slice of tissue. It may be used to remove a tumor or some other type of tissue that requires removal and typically includes a small amount of normal tissue around it. It is easy to repair, does not greatly distort the shape of the underlying organ and leaves just a single stitch line as a residual.
Gliosarcoma is a rare type of glioma, a cancer of the brain that comes from glial, or supportive, brain cells, as opposed to the neural brain cells. Gliosarcoma is a malignant cancer, and is defined as a glioblastoma consisting of gliomatous and sarcomatous components.
Spindle cell carcinoma is a type of cancer that begins in the skin or in tissues that line or cover internal organs and that contains long spindle-shaped cells. It is also called sarcomatoid carcinoma.
In the various fields of healthcare, a population study is a study of a group of individuals taken from the general population who share a common characteristic, such as age, sex, or health condition. This group may be studied for different reasons, such as their response to a drug or risk of getting a disease.
Plaque radiotherapy is a type of radiation therapy used to treat eye tumors. A thin piece of metal with radioactive seeds placed on one side is sewn onto the outside wall of the eye with the seeds aimed at the tumor. It is removed at the end of treatment, which usually lasts for several days.
A nicotine lozenge is a tablet that contains a dose of nicotine polacrilex which dissolves slowly in the mouth to release the nicotine. Nicotine lozenges are commonly found in 2mg and 4mg strengths although other strengths may be found. The nicotine is absorbed through the lining of the mouth and enters the blood vessels. It is used as an aid in nicotine replacement therapy (NRT), a process for smoking cessation. People using the lozenge should not smoke because of the increased risk of nicotine poisoning. Combination therapy can be employed by the use of nicotine lozenges and a nicotine patch to increase the chances of quitting tobacco successfully and permanently. The effects of the lozenge may be diminished from drinking anything fifteen minutes prior to taking the lozenge.
Mucinous carcinoma is a type of cancer that arises from epithelial cells; these line certain internal organs and skin, and produce mucin.
A junctional nevus is a mole found in the junction (border) between the epidermis and dermis layers of the skin.
A neuroectodermal tumor is a tumor of the central or peripheral nervous system.
Segmental resection is a surgical procedure to remove part of an organ or gland, as a sub-type of a resection, which might involve removing the whole body part. It may also be used to remove a tumor and normal tissue around it. In lung cancer surgery, segmental resection refers to removing a section of a lobe of the lung. The resection margin is the edge of the removed tissue; it is important that this shows free of cancerous cells on examination by a pathologist.
The National Cancer Institute (NCI) is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. The NCI coordinates the United States National Cancer Program and conducts and supports research, training, health information dissemination, and other activities related to the causes, prevention, diagnosis, and treatment of cancer; the supportive care of cancer patients and their families; and cancer survivorship.
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