Ebola virus disease in the United Kingdom

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Ebola virus disease in the United Kingdom and Ireland has occurred rarely in four cases to date, namely three health workers returning from treating victims of the Ebola virus epidemic in West Africa in 2014 and 2015, and a single case in 1976, when a laboratory technician contracted the disease in a needlestick injury while handling samples from Africa. All cases recovered. As of 2023, no domestic transmission of Ebola has occurred in the United Kingdom or Ireland.

Contents

Infected in the UK and Ireland

On 5 November 1976, Geoffrey Platt, a laboratory technician at the former Microbiological Research Establishment in Porton Down, Wiltshire, contracted Ebola in an accidental needlestick injury from a contaminated needle while handling samples from Africa. [1] He was treated with human interferon and convalescent serum. The course of his disease was mild and he fully recovered. [2] [3]

Infected outside UK and Ireland

Nurse, 2014

The high-level isolation unit at the Royal Free Hospital, in the Hampstead area of London, received its first case on 24 August 2014. William Pooley, a British nurse who contracted the disease while working in Sierra Leone as part of the relief effort for the Ebola virus epidemic in West Africa, was medically evacuated by the Royal Air Force on a specially-equipped C-17 aircraft. [4] He was released from hospital on 3 September 2014. [5] Pooley delivered the UK's Channel 4 television program Alternative Christmas message in 2014. [6] He was reported to be planning to return to Sierra Leone on 19 October 2014. [7] He also donated blood to support developing a cure for the disease. [7]

Aid worker, 2014

Royal Free Hospital, Hampstead Royal Free Hospital, Hampstead - geograph.org.uk - 275921.jpg
Royal Free Hospital, Hampstead

On 29 December 2014, Pauline Cafferkey, a Scottish aid worker who had just returned from an Ebola treatment centre in Kerry Town in Sierra Leone to Glasgow via Casablanca Airport and London Heathrow Airport, was diagnosed with Ebola virus disease at Glasgow's Gartnavel General Hospital. [8] [9] [10] it was thought she contracted the virus as a result of wearing a visor instead of goggles. [11] Criticism was levelled at screening protocols at UK points of entry, which mainly consisted of taking a person's temperature and asking a series of questions. [12]

After initial treatment in Glasgow, she was transferred to the specialist high-level isolation unit at the Royal Free Hospital in London for longer-term treatment. [9] [13] Contact tracing was carried out on the other passengers who had traveled on the flight from London to Glasgow with her. [13] In January 2015, she experienced a period of critical illness, [14] and underwent intensive medical treatment. [15] In January 2015 she was declared to be free of infection, and released from hospital. [16]

In October 2015, Cafferkey was diagnosed with late complications caused by the Ebola virus hitherto considered unusual, and readmitted to the Royal Free Hospital. The virus had remained in her cerebrospinal fluid and was feared to be in her central nervous system. [17] Her doctors stated that she had been critically ill due to neurological complications from meningitis, and that she had been treated using a highly experimental anti-viral agent. [18] [19] [20] On 12 November the Royal Free Hospital said that Cafferkey had made a full recovery and was no longer infectious. [21]

In February 2016, Cafferkey was readmitted to the Royal Free Hospital due to complications from her infection, [22] but later that month declared not to be infectious and discharged. [23] In October 2016, she was again admitted to hospital, monitored by the infectious diseases unit at Glasgow's Queen Elizabeth University Hospital, [24] but tests for the Ebola virus were negative. [25]

In 2016, proceedings were initiated against Cafferkey by the Nursing and Midwifery Council alleging that she had allowed an incorrect temperature to be recorded during the screening process upon returning to the UK from Sierra Leone in 2014. Following a hearing in September 2016, the charges against her were dismissed after the disciplinary panel was told that she had been impaired by illness at the time. [26]

Military health worker, 2015

On 11 March 2015, a UK military health worker contracted the disease in Sierra Leone while volunteering as a nurse. After testing positive for Ebola she was flown home for treatment at Royal Free Hospital in London. [27] On 27 March 2015 Corporal Anna Cross, the UK military worker who tested positive for Ebola, was the first person in the world to be treated with the experimental Ebola drug MIL 77 and was released from hospital after making a full recovery. The doctors treating her at London's Royal Free Hospital confirmed it is too soon to speculate if the drug helped in her recovery. [28]

Suspected, but not confirmed incidents

Healthcare workers who in January 2015 had sustained needlestick injuries while caring for Ebola patients abroad were put under medical observation, but not found to have contracted the Ebola virus. [29] [30] [31] On 16 March 2015, another UK worker had been sent back to the United Kingdom from Sierra Leone due to fear of having contracted the virus. [32] but did not test positive.

On 17 November Colchester Hospital deep cleaned after a suspected case of the 2022 Uganda Ebola outbreak, [33] which as of December was not confirmed as an Ebola case.

Public health measures

In November 2014, Public Health England established the returning workers scheme, mandating organisations and businesses to register and provide travel details of all staff returning from Ebola affected areas before they travel back to the UK. [34]

In October 2022, the UK Health Security Agency issued a health alert asking providers to considering Ebola in the differential diagnosis of any patient with relevant symptoms returning from areas affected by the outbreak of Sudan ebolavirus in Uganda. [35]

See also

Related Research Articles

<span class="mw-page-title-main">Royal Free Hospital</span> Hospital in London, England

The Royal Free Hospital is a major teaching hospital in the Hampstead area of the London Borough of Camden. The hospital is part of the Royal Free London NHS Foundation Trust, which also runs services at Barnet Hospital, Chase Farm Hospital and a number of other sites. The trust is a founder member of the UCLPartners academic health science centre.

<span class="mw-page-title-main">Gartnavel General Hospital</span> Hospital in Scotland

Gartnavel General Hospital is a teaching hospital in the West End of Glasgow, Scotland. The hospital is located next to the Great Western Road, between Hyndland, Anniesland and Kelvindale. Hyndland railway station is adjacent to the hospital. The name Gartnavel is derived from the Gaelic GartUbhal (apple) – i.e. "a field of apple trees". It is managed by NHS Greater Glasgow and Clyde.

<span class="mw-page-title-main">Ebola</span> Viral hemorrhagic fever of humans and other primates caused by ebolaviruses

Ebola, also known as Ebola virus disease (EVD) and Ebola hemorrhagic fever (EHF), is a viral hemorrhagic fever in humans and other primates, caused by ebolaviruses. Symptoms typically start anywhere between two days and three weeks after infection. The first symptoms are usually fever, sore throat, muscle pain, and headaches. These are usually followed by vomiting, diarrhoea, rash and decreased liver and kidney function, at which point some people begin to bleed both internally and externally. It kills between 25% and 90% of those infected – about 50% on average. Death is often due to shock from fluid loss, and typically occurs between six and 16 days after the first symptoms appear. Early treatment of symptoms increases the survival rate considerably compared to late start. An Ebola vaccine was approved by the US FDA in December 2019.

<span class="mw-page-title-main">Western African Ebola virus epidemic</span> 2013–2016 major disease outbreak

The 2013–2016 epidemic of Ebola virus disease, centered in Western Africa, was the most widespread outbreak of the disease in history. It caused major loss of life and socioeconomic disruption in the region, mainly in Guinea, Liberia and Sierra Leone. The first cases were recorded in Guinea in December 2013; later, the disease spread to neighbouring Liberia and Sierra Leone, with minor outbreaks occurring in Nigeria and Mali. Secondary infections of medical workers occurred in the United States and Spain. In addition, isolated cases were recorded in Senegal, the United Kingdom and Italy. The number of cases peaked in October 2014 and then began to decline gradually, following the commitment of substantial international resources.

Sheik Umar Khan was the chief Sierra Leonean doctor attempting to curb the country's Ebola outbreak in 2014.

<span class="mw-page-title-main">Ebola virus epidemic in Sierra Leone</span>

An Ebola virus epidemic in Sierra Leone occurred in 2014, along with the neighbouring countries of Guinea and Liberia. At the time it was discovered, it was thought that Ebola virus was not endemic to Sierra Leone or to the West African region and that the epidemic represented the first time the virus was discovered there. However, US researchers pointed to lab samples used for Lassa fever testing to suggest that Ebola had been in Sierra Leone as early as 2006.

<span class="mw-page-title-main">Ebola virus epidemic in Guinea</span>

An epidemic of Ebola virus disease in Guinea from 2013 to 2016 represents the first ever outbreak of Ebola in a West African country. Previous outbreaks have been confined to several countries in Sub-Saharan Africa.

<span class="mw-page-title-main">Ebola virus epidemic in Liberia</span> Health disaster in Africa

An epidemic of Ebola virus disease occurred in Liberia from 2014 to 2015, along with the neighbouring countries of Guinea and Sierra Leone. The first cases of virus were reported by late March 2014. The Ebola virus, a biosafety level four pathogen, is an RNA virus discovered in 1976.

<span class="mw-page-title-main">Ebola virus cases in the United States</span>

Four laboratory-confirmed cases of Ebola virus disease occurred in the United States in 2014. Eleven cases were reported, including these four cases and seven cases medically evacuated from other countries. The first was reported in September 2014. Nine of the people contracted the disease outside the US and traveled into the country, either as regular airline passengers or as medical evacuees; of those nine, two died. Two people contracted Ebola in the United States. Both were nurses who treated an Ebola patient; both recovered.

<span class="mw-page-title-main">Responses to the West African Ebola virus epidemic</span>

Organizations from around the world responded to the West African Ebola virus epidemic. In July 2014, the World Health Organization (WHO) convened an emergency meeting with health ministers from eleven countries and announced collaboration on a strategy to co-ordinate technical support to combat the epidemic. In August, they declared the outbreak an international public health emergency and published a roadmap to guide and coordinate the international response to the outbreak, aiming to stop ongoing Ebola transmission worldwide within 6–9 months. In September, the United Nations Security Council declared the Ebola virus outbreak in the West Africa subregion a "threat to international peace and security" and unanimously adopted a resolution urging UN member states to provide more resources to fight the outbreak; the WHO stated that the cost for combating the epidemic will be a minimum of $1 billion.

<span class="mw-page-title-main">Ebola virus disease in Spain</span>

In 2014, Ebola virus disease in Spain occurred due to two patients with cases of the disease contracted during the Ebola virus epidemic in West Africa; they were medically evacuated. A failure in infection control in the treatment of the second patient led to an isolated infection of Ebola virus disease in a health worker in Spain itself. The health worker survived her Ebola infection, and has since been declared infection-free.

<span class="mw-page-title-main">West African Ebola virus epidemic timeline</span>

This article covers the timeline of the 2014 Ebola virus epidemic in West Africa and its outbreaks elsewhere. Flag icons denote the first announcements of confirmed cases by the respective nation-states, their first deaths, and their first secondary transmissions, as well as relevant sessions and announcements of agencies such as the World Health Organization (WHO), the U.S. Centers for Disease Control (CDC), and NGOs such as Doctors Without Borders; medical evacuations, visa restrictions, border closures, quarantines, court rulings, and possible cases of zoonosis are also included.

<span class="mw-page-title-main">Ebola virus disease in Mali</span>

Ebola virus disease in Mali occurred in October 2014, leading to concern about the possibility of an outbreak of Ebola in Mali. A child was brought from Guinea and died in the northwestern city of Kayes. Mali contact traced over 100 people who had contact with the child; tracing was completed in mid-November with no further cases discovered. In November, a second unrelated outbreak occurred in Mali's capital city, Bamako. Several people at a clinic are thought to have been infected by a man traveling from Guinea. On January 18, Mali was declared Ebola-free after 42 days with no new cases. There had been a cumulative total of eight cases with six deaths.

The following lists events that happened during 2014 in Sierra Leone.

<span class="mw-page-title-main">Cultural effects of the Western African Ebola virus epidemic</span>

The Ebola virus epidemic in West Africa has had a large effect on the culture of most of the West African countries. In most instances, the effect is a rather negative one as it has disrupted many Africans’ traditional norms and practices. For instance, many West African communities rely on traditional healers and witch doctors, who use herbal remedies, massage, chant and witchcraft to cure just about any ailment. Therefore, it is difficult for West Africans to adapt to foreign medical practices. Specifically, West African resistance to Western medicine is prominent in the region, which calls for severe distrust of Western and modern medical personnel and practices.(see Ebola conspiracies below.)

<span class="mw-page-title-main">United Kingdom aid efforts for the 2014 Ebola epidemic in West Africa</span>

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<span class="mw-page-title-main">Kerry Town</span> Place in Western Area, Sierra Leone

Kerry Town is a village in the Rural District in the Western Area of Sierra Leone. the town is located about 31 kilometres (19 mi) from the national capital, Freetown, which lies to the west-north-west. The population of Kerry Town is largely from the Krio ethnic group. The Treatment of the Ebola Virus clinic is located in Kerry Town.

Pauline Cafferkey is a Scottish nurse and aid worker who contracted Ebola virus disease in 2014 while working in Sierra Leone as part of the medical aid effort during the West African Ebola virus epidemic. She survived the illness.

<span class="mw-page-title-main">Ebola in Nigeria</span>

Cases of the Ebola virus disease in Nigeria were reported in 2014 as a small part of the epidemic of Ebola virus disease which originated in Guinea that represented the first outbreak of the disease in a West African country. Previous outbreaks had been confined to countries in Central Africa.

<span class="mw-page-title-main">West African Ebola virus epidemic timeline of reported cases and deaths</span>

In March 2014, the World Health Organization (WHO) reported a major Ebola outbreak in Guinea, a western African nation, the disease then rapidly spread to the neighboring countries of Liberia and Sierra Leone with smaller outbreaks occurring in Senegal, Nigeria, and Mali; the resulting West African Ebola virus epidemic is the largest Ebola outbreak ever documented.

References

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  6. "UEA graduate to deliver Channel 4 Christmas message". 23 December 2014. Archived from the original on 23 December 2014. Retrieved 23 December 2014.
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  9. 1 2 Severin Carrell; Libby Brooks; Lisa O'Carroll (29 December 2014). "Ebola case confirmed in Glasgow". The Guardian.
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  33. "Hospital deep-cleaned over possible Ebola case". ITV News. 17 November 2022. Retrieved 17 November 2022.
  34. "Ebola: returning workers scheme (RWS)". GOV.UK. 15 July 2015. Retrieved 9 December 2022.
  35. "Ebola: outbreak of Sudan ebolavirus in Uganda". GOV.UK. 6 October 2022. Retrieved 9 December 2022.

Further reading