Frank Fenner

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Frank Fenner

AC, CMG, MBE, FRS, FAA
Professor Frank Fenner.jpg
Born
Frank Johannes Fenner

21 December 1914
Died22 November 2010(2010-11-22) (aged 95) [1]
NationalityAustralian
Other namesFrank John Fenner (after 1938)
Education University of Adelaide
Occupation Virology
Employer Australian National University
Known forEradication of smallpox
Control of Australia's rabbit plague
Spouse(s)Ellen Margaret Bobbie Roberts
Parent(s)Albert Charles Fenner and Peggy Fenner

Frank John Fenner AC CMG MBE FRS FAA (21 December 1914 – 22 November 2010) was an Australian scientist with a distinguished career in the field of virology. His two greatest achievements are cited as overseeing the eradication of smallpox, [2] and the control of Australia's rabbit plague through the introduction of Myxoma virus. [3]

Contents

The Australian Academy of Science awards annually the prestigious Fenner Medal for distinguished research in biology by a scientist under 40 years of age. [4] [5]

Early life

Frank Johannes Fenner was born in Ballarat in 1914, but the family moved to Adelaide, South Australia in November 1916. Frank attended Rose Park Primary School and Thebarton Technical School. He attended the University of Adelaide, where he earned degrees in medicine and surgery in 1938. That year, uneasy about Hitler's rise, he legally changed his middle name to John. From 1940–1946 he was a Captain and Major in the Australian Army Medical Corps with service in Australia, Palestine, Egypt, New Guinea, and Borneo, [6] as medical officer in field ambulance and casualty clearing station, pathologist to general hospital, and malariologist. For his work in combating malaria in Papua New Guinea he was made a Member of the Order of the British Empire in 1945. [7] [8]

Following his war-time service he was recruited by Frank Macfarlane Burnet to work at the Walter and Eliza Hall Institute of Medical Research in Melbourne. Initially they worked on smallpox in mice, for which he coined the term 'mousepox,' and later on poxvirus genetics.

In 1949 he received a fellowship to study at the Rockefeller Institute for Medical Research in New York City, he worked on mycobacterium Bairnsdale bacillus, which causes Buruli ulcer, the third most important mycobacterial disease worldwide after tuberculosis and leprosy. Here he worked with and was influenced by René Dubos, who is one of the claimed originators of the phrase "Think Globally, Act Locally".

Career in Canberra

Returning to Australia in 1949, he was appointed Professor of Microbiology at the new John Curtin School of Medical Research at the Australian National University, Canberra. Here he began studying viruses again, in particular the myxoma virus.

Throughout the 1940s and 1950s Australia had severe rabbit plagues. Fenner's work on the myxoma virus showed that initially it killed rabbits in 9 to 11 days and was 99.5% lethal. Under heavy selection pressure, the few rabbits that survived developed resistance, which meant that the pest was never completely eradicated, but their numbers were reduced. Prior to the release of the virus as a biological control for the rabbits, Fenner, Frank Macfarlane Burnet, and Ian Clunies Ross famously injected themselves with myxoma virus, to prove it was not dangerous for humans.

Fenner was Director of the John Curtin School from 1967 to 1973. In 1977, he was named the chairman of the Global Commission for the Certification of Smallpox Eradication. The last known case of naturally transmitted smallpox occurred in Somalia in 1977. Professor Fenner announced the eradication of the disease to the World Health Assembly on 8 May 1980. [6] This success story is regarded as the greatest achievement of the World Health Organization. Before its eradication, smallpox was one of the world's most virulent viruses, responsible for millions of deaths, and leaving many of the victims who survived with disfiguring scars for life.

Professor Fenner had an abiding interest in the environment, and was the foundation Director of the Centre for Resources and Environmental Studies at the ANU (1973), where he worked until his retirement in 1979, and which became part of the Fenner School of Environment and Society in 2007. [9] He was a keen supporter of Australia having an ecologically, socially sustainable population. He was Emeritus Professor at the John Curtin School of Medical Research.

In an interview with The Australian on 16 June 2010, he predicted the extinction of the human race within a century, primarily as the result of human overpopulation, environmental degradation and climate change. [6] [10] [11]

He died in Canberra on the morning of 22 November 2010 after a brief illness, and days after the birth of his first great-grandchild. [12]

Personal life

In 1944 Fenner met Bobbie Roberts. Ellen Margaret 'Bobbie' Roberts was a trained midwife and nurse. During World War II she worked on malaria with the Australian Army Nursing Service and through her work met Fenner. [13] Shortly after they met they married in a Catholic ceremony (despite Fenner being an atheist). [14] While keen to have children, the couple were infertile and with Bobbie having a hysterectomy in 1949 they decided to adopt. They subsequently adopted two children. Marilyn Aldus Fenner was born on 27 June 1950. Her biological parents were unknown. Victoria Fenner (born 1 March 1943) was adopted later at the request of her father (Fenner's younger brother Tom) after the death in a fire of Victoria's mother (Beverley Slaney). [15]

On 30 March 1958, Victoria Fenner, shot and killed herself, with the assistance of another child, Catherine Webb. The coronial inquiry heard she had been passing through a period of extreme mental and spiritual disturbance and the coroner declared her death a suicide. [16] Fenner himself was unable to fathom a motive, other than she was upset from reading Neville Shute's book, On the Beach . [17]

Bobbie Fenner was diagnosed with cancer in 1989 and eventually died in 1994. Marilyn Fenner and her family then moved into the family home and looked after her father until his death. [18]

Publications

Honours

Of the many honours Professor Fenner received throughout his career, there are the following:

Related Research Articles

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References

  1. Henderson, Donald A. (2011). "Frank Fenner (1914–2010) A guiding light of the campaign to eradicate smallpox". Nature. 469 (7328): 35. doi: 10.1038/469035a . PMID   21209651.
  2. Frank F. Fenner, Donald A. Henderson, Isao Arita, Zdeněk Ježek, Ivan D. Ladnyi Smallpox and its Eradication World Health Organization Geneva, 1988
  3. Boyden, S.; Blanden, R.; Mims, C. (2013). "Frank John Fenner FAA. 21 December 1914 -- 22 November 2010". Biographical Memoirs of Fellows of the Royal Society . 59: 125–144. doi:10.1098/rsbm.2013.0009.
  4. "Archived copy". Archived from the original on 13 April 2014. Retrieved 13 April 2014.CS1 maint: archived copy as title (link)
  5. "UWA scientist wins Academy Award".
  6. 1 2 3 Grimes, William (25 November 2010). "Frank Fenner Dies at 95; Tracked End of Smallpox". The New York Times.
  7. 1 2 It's an Honour: MBE
  8. 1 2 Citation record of MBE
  9. Fenner School of Environment and Society website
  10. Jones, Cheryl (15 June 2010). "Fenner sees no hope for humans". The Australian.
  11. Edwards, Lin (23 June 2010). "Humans will be extinct in 100 years says eminent scientist". Phys.org . Retrieved 2 July 2020.
  12. "Scientist Fenner dies aged 95". 22 November 2010.
  13. Encyclopaedia of Australian Science
  14. Chapter 3, Nature, Nurture and Chance: the lives of Frank and Charles Fenner
  15. Chapter 5, Nature, Nurture and Chance: the lives of Frank and Charles Fenner
  16. Suicide Finding in Death of Girl 15 in Canberra, Sydney Morning Herald, 20 June 1958, p3
  17. Chapter 5, Nature, Nurture and Chance: the lives of Frank and Charles Fenner
  18. Chapter 11, Nature, Nurture and Chance: the lives of Frank and Charles Fenner
  19. It’s an Honour: CMG
  20. "Macfarlane Burnet Medal and Lecture". Australian Academy of Science. Retrieved 22 February 2017.
  21. It's an Honour: AC
  22. "Archived copy". Archived from the original on 29 July 2013. Retrieved 14 August 2013.CS1 maint: archived copy as title (link)
  23. "Jon Stanhope appalled by ACT federal seat renamed from Fraser to Fenner". 24 November 2015.
  24. "Voters call out AEC on Fraser electorate renaming". 19 October 2015.