Giant-cell tumor of the tendon sheath

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Giant-cell tumor of the tendon sheath
Giant cell tumor of tendon sheath histopathology(1).jpg
Histopathology of giant-cell tumor of the tendon sheath arising in hand finger. Hematoxylin and eosin stain.
Specialty Oncology, rheumatology   OOjs UI icon edit-ltr-progressive.svg

Giant-cell tumor of the tendon sheath, also known as giant-cell synovioma and localized nodular tenosynovitis, [1] is a firm lesion, measuring 1 to 3 cm in diameter, and is most commonly attached to the tendons of the fingers, hands, and wrists, with a predilection for the flexor surfaces. [1] [2] Giant-cell tumor of tendon sheaths most often affect the wrist and fingers of males and females from the ages of 20-50 . These tumors are typically painless and can cause cortical erosion. Surgery to remove the tumor is a common treatment, though there is a risk of recurrence which is related to the mitotic count [3] .


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  1. 1 2 Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 1820. ISBN   978-1-4160-2999-1.
  2. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN   0-7216-2921-0.
  3. Linney, L. S.; Al-Hassani, F.; Pikturnaite, J.; Mathew, B.; Thornton, D.; Wade, Ryckie. G.; Pinder, Richard. M. (1 June 2019). "Tenosynovial giant cell tumours of the hand: A multicentre case-control study". Journal of Plastic, Reconstructive & Aesthetic Surgery. 72 (6): 918–923. doi:10.1016/j.bjps.2019.01.021. ISSN   1748-6815.
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