Hydroxyestriol

Last updated April 08, 2019

Hydroxyestriol may refer to:

2-Hydroxyestriol, also known as estra-1,3,5(10)-triene-2,3,16α,17β-tetrol, is an endogenous catechol estrogen and metabolite of estriol. It is a suspected carcinogen of carcinogenicity category 2.

4-Hydroxyestriol, also known as estra-1,3,5(10)-triene-3,4,16α,17β-tetrol, is an endogenous catechol estrogen and metabolite of estriol. It has been found in pregnancy urine.

Estetrol (E4), or oestetrol, is a weak estrogen steroid hormone which is found in detectable levels only during pregnancy. It is produced exclusively by the fetal liver. Estetrol is closely related to estriol, which is also a weak estrogen that is found in high quantities only during pregnancy. Along with estradiol (E2), estrone (E1), and estriol (E3), estetrol is a major estrogen in the body, although only during pregnancy.

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Related Research Articles

The molecular formula C₁₈H₂₄O₄ may refer to:

A catechol estrogen is a steroidal estrogen that contains catechol (1,2-dihydroxybenzene) within its structure. The catechol estrogens are endogenous metabolites of estradiol and estrone and include the following compounds:

Estriol (E3), sold under the brand name Ovestin among others, is an estrogen medication and naturally occurring steroid hormone which is used in menopausal hormone therapy. It is also used in veterinary medicine as Incurin to treat urinary incontinence due to estrogen deficiency in dogs. The medication is taken by mouth in the form of tablets, as a cream that is applied to the skin, as a cream or pessary that is applied in the vagina, and by injection into muscle.

Estetrol (E4), tentative brand names Donesta (alone) and Estelle/PeriNesta, is an estrogen medication and naturally occurring steroid hormone which is under development for use as a birth control pill in combination with a progestin, in menopausal hormone therapy to treat symptoms such as vaginal atrophy, hot flashes, and bone loss, and for the treatment of breast cancer, prostate cancer, osteoarthritis, and migraine. It is taken by mouth.