Ly6/plaur domain containing 5

LYPD5
Identifiers
Aliases	LYPD5 , PRO4356, LY6/PLAUR domain containing 5
External IDs	MGI: 1924192 HomoloGene: 18797 GeneCards: LYPD5
Gene location (Human)
Chr.	Chromosome 19 (human) [1]
End	43,827,206 bp [1]
Gene location (Mouse)
Chr.	Chromosome 7 (mouse) [2]
End	24,355,109 bp [2]
Gene ontology
Molecular function	• laminin binding ;
Cellular component	• membrane ; • anchored component of membrane ; • extracellular region ; • plasma membrane ;
Biological process	• cell-matrix adhesion ;
	Sources:Amigo / QuickGO
Orthologs
	284348
	76942
	ENSG00000159871
	ENSMUSG00000030484
	Q6UWN5
	Q9D7Z7
	NM_001031749 ; NM_001288763 ; NM_182573
	NM_029806
	NP_001026919 ; NP_001275692 ; NP_872379
	NP_084082
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated April 21, 2019

LY6/PLAUR domain containing 5 is a protein that in humans is encoded by the LYPD5 gene. ^[5]

Protein biological molecule consisting of chains of amino acid residues

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity.

In biology, a gene is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic trait. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that constitute life.

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000159871 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030484 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ "Entrez Gene: LY6/PLAUR domain containing 5" . Retrieved 2016-04-05.

Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832  . PMID 19913121.

In computing, a Digital Object Identifier or DOI is a persistent identifier or handle used to identify objects uniquely, standardized by the International Organization for Standardization (ISO). An implementation of the Handle System, DOIs are in wide use mainly to identify academic, professional, and government information, such as journal articles, research reports and data sets, and official publications though they also have been used to identify other types of information resources, such as commercial videos.

PubMed Central (PMC) is a free digital repository that archives publicly accessible full-text scholarly articles that have been published within the biomedical and life sciences journal literature. As one of the major research databases within the suite of resources that have been developed by the National Center for Biotechnology Information (NCBI), PubMed Central is much more than just a document repository. Submissions into PMC undergo an indexing and formatting procedure which results in enhanced metadata, medical ontology, and unique identifiers which all enrich the XML structured data for each article on deposit. Content within PMC can easily be interlinked to many other NCBI databases and accessed via Entrez search and retrieval systems, further enhancing the public's ability to freely discover, read and build upon this portfolio of biomedical knowledge.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000159871 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030484 - Ensembl, May 2017

[3] "Human PubMed Reference:".

[4] "Mouse PubMed Reference:".

[entrez-5] "Entrez Gene: LY6/PLAUR domain containing 5" . Retrieved 2016-04-05.

Ly6/plaur domain containing 5

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References

Further reading