Razi Cov Pars

Last updated

Razi Cov Pars
Vaccine description
Target SARS-CoV-2
Vaccine type Protein subunit
Clinical data
Routes of
Intramuscular, Intranasal

Razi Cov Pars is a COVID-19 vaccine candidate developed by the Iranian Razi Vaccine and Serum Research Institute. [1] [2] [3]


It's the second Iranian COVID-19 vaccine reaching human trials [1] and is currently in phase III of clinical research during which it's compared to the Sinopharm BIBP vaccine. [4] [5]

Medical uses

It requires three doses given day 0 (intramuscular), day 21 (intramuscular) and day 51 (intranasal spray). [3]


Razi Cov Pars is a recombinant protein subunit vaccine containing the SARS-CoV-2 spike protein. [2]


It's planned to produce one million doses of the vaccine each month as of September 2021. [4]

Clinical trials

Clinical trials of Razi Cov Pars
PhaseRegistration numberStartNumber of participantsAge of participantsRef
I IRCT20201214049709N1 21 January 202113330 (5 µg/200µL)

30 (10 µg/200µL)

30 (20 µg/200µL)

30 (placebo)

13 (sentinel)

18-50 years [2]
II IRCT20201214049709N2 13 April 202150018-70 years [3]
III IRCT20201214049709N3 29 August 202141,12820,5640 (placebo)

20,564 (Sinopharm BIBP vaccine)

18+ years [5]

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  1. 1 2 Mehdi, Syed Zafar (7 February 2021). "Iran unveils second homegrown COVID-19 vaccine". Anadolu Agency. Retrieved 22 April 2021.
  2. 1 2 3 "Phase I, Safety and Immunogenicity of Razi SARS-CoV-2 recombinant Spike protein vaccine (Razi Cov Pars), in healthy adults aged 18-55 years; parallel 4 arms design (adjuvant only and three vaccine doses of 5, 10, and 20 µg/200µl); a Randomised, double blind, clinical trial". irct.ir. Iranian Registry of Clinical Trials. Retrieved 21 March 2021.
  3. 1 2 3 "Phase II, Safety and Immunogenicity of RAZI SARS-CoV-2 recombinant Spike protein vaccine (RAZI Cov Pars) in adults aged 18-70 years; a Randomised, double blind, parallel 2 arms clinical trial". Iranian Registry of Clinical Trials. Retrieved 22 April 2021.
  4. 1 2 "COVID-19 vaccine Razi Cov Pars starts third clinical trial phase". Tehran Times. 27 August 2021. Retrieved 30 August 2021.
  5. 1 2 "IRCT | Comparison of the safety and efficacy of Razi SARS-CoV-2 recombinant Spike protein (Razi Cov Pars) and Sinopharm vaccines in adults aged 18 and over, a phase III randomised, double blind, non-inferiority clinical trial". en.irct.ir. Retrieved 30 August 2021.