René Favaloro

Last updated
René Favaloro
Rene Favaloro.JPG
Born
René Gerónimo Favaloro

July 14, 1923
DiedJuly 29, 2000(2000-07-29) (aged 77)
Buenos Aires, Argentina
Cause of death Suicide by gunshot
Nationality Argentine
Alma mater National University of La Plata
Years active1949–2000
Spouse(s)María Antonia Delgado (1951–1998)
Parent(s)Juan Manuel Favaloro and Geni Ida Raffaeli [1]
Awards Prince Mahidol Award (1998), Order of the Sun of Peru (1973), Order of Merit of the Italian Republic (1978), Canada Gairdner International Award (1987), Golden Plate Award (1993), Konex Award (1993)
Signature
Firma de Favaloro.jpg

René Gerónimo Favaloro (July 14, 1923 – July 29, 2000) was an Argentine cardiac surgeon and educator best known for his pioneering work on coronary artery bypass surgery using the great saphenous vein.

Contents

Early life

Favaloro was born in 1923 [2] and raised in La Plata; his grandparents were Sicilians. [3] At an early age, he developed a love for football, favoring Gimnasia y Esgrima La Plata, a popular club in the city. [4]

In 1936, Favaloro was admitted into the Colegio Nacional de La Plata. After graduating from high school, he was admitted to the School of Medicine at the National University of La Plata. During his third year, he began his medical residency at the Hospital Policlínico San Martín, a medical center that received the most complicated cases from much of Buenos Aires province. This residency brought him into contact with patients for the first time. He attended procedures carried out by professors José María Mainetti and Federico E. B. Christmann, from whom he learned the simplicity and standardization that he would later apply to cardiovascular surgery, one of his many great contributions to cardiovascular operating techniques. Favaloro graduated with a medical degree in 1949. [4]

He then applied for a position as a medical auxiliary, but the offer required him to enroll in the Peronist Party, which he did not accept. He moved instead to a small town named Jacinto Aráuz in La Pampa Province after being offered a job as the town's doctor; when the resident doctor died, he succeeded him and brought his brother Juan José into the clinic. He married María Antonia Delgado in 1951. [4]

Favaloro and his brother endeavored to improve the general level of health in what was then a remote region. They trained and educated the general public, teachers, and nurses and improved health-care delivery. They equipped the town with an operating room and X-ray and improved the laboratory, thereby providing essential surgical and diagnostic tools.[ citation needed ]

Thoracic surgery

Favaloro with F. Mason Sones, Jr., at the Cleveland Clinic Drs Rene Favaloro and Mason Sones c1970 A0353.jpg
Favaloro with F. Mason Sones, Jr., at the Cleveland Clinic

Favaloro became interested in developments in cardiovascular intervention, and developed an enthusiasm for thoracic surgery. During a visit to La Plata, he met Professor Mainetti, who pointed him in the direction of the Cleveland Clinic. Although in the beginning he had doubts about leaving his profession as a rural physician, he thought that he could make a greater contribution to the community on returning from the United States. With few resources and rudimentary English, he decided to travel to Cleveland. He first worked as a resident and later as a member of the surgical team, working with Donald B. Effler, head of cardiovascular surgery, F. Mason Sones, Jr., who was in charge of the Angiography Laboratory, and William L. Proudfit, head of the Department of Cardiology.

In the beginning, the major part of his work involved valvular and congenital diseases; later on, he became interested in other areas. Every day, having hardly finished working in the operating room, Favaloro would spend hours and hours reviewing coronary angiograms and studying coronary arteries and their relation with the cardiac muscle. The laboratory of Sones, father of the coronary angiography, had the largest collection of angiograms in the United States.

In early 1967, Favaloro began to consider the possibility of using the saphenous vein in coronary surgery. He put his ideas into practice for the first time in May of that year. The basic principle was to bypass a diseased (obstructed) segment of a coronary artery in order to deliver blood flow distally. The standardization of this technique, called coronary artery bypass surgery, was the fundamental work of his career, and ensured that his prestige would transcend the limits of his country, as the procedure radically changed the treatment of coronary disease. In 1970, he published one of his best-known volumes, Surgical Treatment of Coronary Arteriosclerosis.

The Favaloro Foundation

Favaloro enjoys a light moment with Nobel Laureate Dr. Luis Leloir and Leloir's wife, Amelia. Amelia Favaloro Leloir.jpg
Favaloro enjoys a light moment with Nobel Laureate Dr. Luis Leloir and Leloir's wife, Amelia.

Favaloro returned to Argentina in 1971 with the dream of developing a center of excellence similar to the Cleveland Clinic, that combined medical attention, research, and education.[ citation needed ]

Bearing that in mind, he founded the Fundación Favaloro in 1975 along with several collaborators. He took pride in having trained more than 450 residents from all over Argentina and the Americas. Favaloro contributed to raise the standard level of his specialty for the benefit of patients through innumerable courses, seminars, and conferences organized by the Fundación, among them the distinguished "Cardiology for the Consultant" (Cardiología para el Consultante), held every two years.

In 1980 Favaloro established the "Basic Investigation Laboratory" (Laboratorio de Investigación Básica), which was long financed with his own money and which, at the time, depended upon the support of the Research and Teaching Department of the Fundación Favaloro. Subsequently, it became the Institute of Research in Basic Sciences of the University Institute of Biomedical Sciences (Instituto de Investigación en Ciencias Básicas del Instituto Universitario de Ciencias Biomédicas) which in turn, was transformed into the Universidad Favaloro in August 1998.[ citation needed ]

In 1992 the nonprofit Favaloro Foundation Institute of Cardiology and Cardiovascular Surgery (Instituto de Cardiología y Cirugía Cardiovascular de la Fundación Favaloro) opened in Buenos Aires. With the motto "advanced technology in the service of medical humanism", this institute offers highly specialized services of cardiology, cardiovascular surgery and heart, lung, cardiopulmonary, liver, kidney, and bone marrow transplants, among other areas. Favaloro focused his career there, surrounded by a selected group of professionals. One of his more famous patients was boxing promoter and Luna Park arena owner Tito Lectoure, on whom Dr. Favaloro operated in 1990. It should be mentioned, however, that despite the immense costs of bypass surgery, Dr Favaloro operated daily on indigent patients, something that he felt was both a necessity and his obligation.

He kept his emphasis on disease prevention and promoting basic rules of hygiene to reduce mortality rate. With that objective, the Fundación Favaloro researches illness detection and prevention programs. Also, many publications were released by the Centro Editor de la Fundación Favaloro (Publishing Center of the Favaloro Foundation), which ceased to operate in 2000. The Favaloro Foundation is currently one of the largest institutions dedicated to cardiology in the Americas.[ citation needed ]

Death

By 2000, Argentina was submerged in an economic and political crisis, and the Favaloro Foundation was US$18 million in debt. On repeated occasions, Favaloro petitioned the Argentine government to aid the Foundation, but never received an official response, nor would the director of the PAMI public medical insurance agency, Horacio Rodríguez Larreta, agree to pay the agency's debt to the Foundation. [5] On July 29, 2000, at age 77, Favaloro fatally shot himself in the chest. [6]

Following his suicide, it was revealed that he had written a letter to Argentine President Fernando de la Rúa, that had never been read, in which he expressed being tired of "being a beggar in his own country," and asked for de la Rúa's help to raise money for the Foundation.

Although his suicide is often linked to the Foundation’s financial difficulties, the letter clearly shows Favaloro felt overwhelmed by the corruption of the health system and that he could not fight against this powerful organization[ ambiguous ]. In the letter, he refers to himself as “Don Quixote” in his lonely battle against the giants. Aggravating this situation was that Favaloro had never recovered from the death of his wife in 1998. [4] Following her death, he had resolved to marry one of his longtime colleagues and coauthors, Diana Truden; she lived with Favaloro during his final days and was in his Palermo neighborhood house when he died by suicide. [7]

Recognitions and distinctions

Favaloro was an active member of 26 societies, corresponding of 4, and honorary of 43. He received innumerable international distinctions. The ones that stand out are: John Scott Prize 1979, granted by Philadelphia; the creation of the Chair of Cardiovascular Surgery "Dr René G. Favaloro" (Tel Aviv University, Israel, 1980); the distinction of the Fundación Conchita Rábago de Giménez Díaz (Madrid, Spain, 1982); the Teacher Prize of Argentinian Medicine (1986); the Distinguished Alumnus Award of the Cleveland Clinic Foundation (1987); The Gairdner Foundation International Award, granted by the Gairdner Foundation (Toronto, Canada, 1987); the René Leriche Prize 1989, granted by the International Surgery Society; the Gifted Teacher Award, granted by the American College of Cardiology (1992); the Golden Plate Award of the American Academy of Achievement (1993); [8] the Diamond Konex Award as the most important scientist in the last decade in his country (Argentina, 1993); and the Prince Mahidol Award, granted by His Majesty the King of Thailand (Bangkok, Thailand, 1999).

In 2007, he was named the second-greatest Argentine of all time, on the TV show El Gen Argentino .

On July 12, 2019, Google showed a Doodle celebrating what would have been his 96th birthday. [9]

Favaloro on television

Favaloro participated in educational programming for the public, distinguishing himself in the television series The Great Medical Themes, and in numerous conferences in Argentina and throughout the world on topics such as medicine, education, and modern society. He was also mentioned in the documentary movie Forks Over Knives .

Works

René Favaloro published more than three hundred works in his specialty. Owing to his passion for history, he also wrote two books about General José de San Martín.

Related Research Articles

Angioplasty minimally invasive, endovascular procedure to widen narrowed or obstructed arteries or veins, typically to treat arterial atherosclerosis.

Angioplasty, also known as balloon angioplasty and percutaneous transluminal angioplasty (PTA), is a minimally invasive endovascular procedure used to widen narrowed or obstructed arteries or veins, typically to treat arterial atherosclerosis. A deflated balloon attached to a catheter is passed over a guide-wire into the narrowed vessel and then inflated to a fixed size. The balloon forces expansion of the blood vessel and the surrounding muscular wall, allowing an improved blood flow. A stent may be inserted at the time of ballooning to ensure the vessel remains open, and the balloon is then deflated and withdrawn. Angioplasty has come to include all manner of vascular interventions that are typically performed percutaneously.

Coronary artery bypass surgery surgical procedure to restore normal blood flow to an obstructed coronary artery

Coronary artery bypass surgery, also known as coronary artery bypass graftsurgery, and colloquially heart bypass or bypass surgery, is a surgical procedure to restore normal blood flow to an obstructed coronary artery. A normal coronary artery transports blood to the heart muscle itself, not through the main circulatory system.

A vascular bypass is a surgical procedure performed to redirect blood flow from one area to another by reconnecting blood vessels. Often, this is done to bypass around a diseased artery, from an area of normal blood flow to another relatively normal area. It is commonly performed due to inadequate blood flow (ischemia) caused by atherosclerosis, as a part of organ transplantation, or for vascular access in hemodialysis. In general, someone's own vein (autograft) is the preferred graft material for a vascular bypass, but other types of grafts such as polytetrafluoroethylene (Teflon), polyethylene terephthalate (Dacron), or a different person's vein (allograft) are also commonly used. Arteries can also serve as vascular grafts. A surgeon sews the graft to the source and target vessels by hand using surgical suture, creating a surgical anastomosis.

José María Mainetti was an Argentine physician, surgeon and oncologist.

Favaloro University Private university in Argentina

The Favaloro University is a private university in the city of Buenos Aires in Argentina. It was founded by surgeon René Favaloro in 1992; it obtained its definitive authorization on October 23, 2003 by decree 963/03 of president Néstor Kirchner. Favaloro did not see his project completely realised, for he committed suicide a few years before completion.

Bernard Lown American cardiologist developer of the DC defibrillator and the cardioverter, as well as a recipient of the Nobel Peace Prize

Bernard Lown is the original developer of the direct current defibrillator and the cardioverter. Lown developed the direct current defibrillator for cardiac resuscitation and the cardioverter for correcting rapid disordered heart rhythms, and introduced a new use for the drug lidocaine to control heartbeat disturbances.

The Favaloro Foundation is an Argentine scientific institution dedicated to medical teaching and research. It was founded in 1975 by René Favaloro with the support of the Cleveland Clinic in the United States where Favaloro worked for many years.

Valentin Fuster Spanish cardiologist

Valentín Fuster Carulla is a Spanish-American cardiologist.

Rafael Hernández National College Public secondary school in La Plata, Buenos Aires, Argentina

The Rafael Hernández National College is one of the four public high schools that are part of the National University of La Plata, in the City of La Plata, Argentina. The Colegio Nacional aegis denotes a school belonging to the system of national secondary schools. The other constituent high schools associated with this university are the Víctor Mercante Lyceum, the "Bachillerato de Bellas Artes" and the Inchausti School for Agricultural Education.

David Sabiston American surgeon

David Coston Sabiston, Jr., M.D.,, F.A.C.S. was an early innovator in cardiac surgery. In 1962, he performed a seminal procedure that paved the way for modern coronary-bypass surgery, grafting a vein from a patient's leg to bypass a blocked coronary artery during open-heart surgery.

F. Mason Sones American physician

F. Mason Sones, Jr. was an American physician whose pioneering work in cardiac catheterization was instrumental in the development of both coronary artery bypass surgery and interventional cardiology.

Myocardial bridge

A myocardial bridge (MB) is a congenital heart defect in which one of the coronary arteries tunnels through the heart muscle itself (myocardium). In normal patients, the coronary arteries rest on top of the heart muscle and feed blood down into smaller vessels which then take blood into the heart muscle itself. However, if a band of muscle forms around one of the coronary arteries during the fetal stage of development, then a myocardial bridge is formed - a "bridge" of heart muscle over the artery. Each time the heart squeezes to pump blood, the band of muscle exerts pressure and constricts the artery, reducing blood flow to the heart. This defect is present from birth. It is important to note that even a very thin ex. < 1 mm and/or short ex. 20 mm MB can cause significant symptoms. MBs can range from a few mm in length to 10 cm or more.

Endoscopic vessel harvesting (EVH) is a surgical technique that may be used in conjunction with coronary artery bypass surgery. For patients with coronary artery disease, a physician may recommend a bypass to reroute blood around blocked arteries to restore and improve blood flow and oxygen to the heart. To create the bypass graft, a surgeon will remove or "harvest" healthy blood vessels from another part of the body, often from the patient's leg or arm. This vessel becomes a graft, with one end attaching to a blood source above and the other end below the blocked area, creating a "conduit" channel or new blood flow connection across the heart.

Purshotam Lal is an Indian cardiologist and chairman and director of Interventional Cardiology of the Metro Group of Hospitals. He has been awarded the Padma Vibhushan (2009), Padma Bhushan, and Padma Shree. He specializes in non-surgical closure of heart holes (ASD/VSD), non-surgical replacement of valves, and treatment of multiple sclerosis.

Marcelo Mendieta Argentine journalist

José Luis Marcelo Ventecol Mendieta is an Argentine journalist. He was born on a farm in Orán, Salta, but was registered in the Civil Registry in Jujuy.

Ulrich Sigwart is a cardiologist known for his pioneering role in the conception and clinical use of vascular stents. He also introduced a non-surgical intervention for the treatment of hypertrophic obstructive cardiomyopathy.

A hybrid cardiac surgical procedure in a narrow sense is defined as a procedure that combines a conventional surgical part with an interventional part, using some sort of catheter-based procedure guided by fluoroscopy imaging in a hybrid OR without interruption. A wider definition includes a clinically connected succession of a catheter intervention and a surgical procedure with a time gap.

In medicine, vein graft failure (VGF) is a condition in which vein grafts, which are used as alternative conduits in bypass surgeries, get occluded.

Uwe Klima is UAE based professor of surgery and a faculty member at the Hannover Medical School, Germany. He also is the medical and managing director at German Heart Centre, Dubai.

References

  1. Larocca, Bruno (2013-06-13). "El caso del Dr. Favaloro" [The Case of Dr. Favaloro]. Gatopardo (in Spanish). Retrieved 2019-07-12.
  2. "Rene Favaloro: A pioneer in heart bypass surgery". Aljazeera.com. Retrieved 12 July 2019.
  3. "Omaggio delle Eolie al cardiochirurgo inventore del by-pass". Lisolaweb.com. March 31, 2008.
  4. 1 2 3 4 "Así vivió y amó el corazón de un genio". Gente.com.ar.
  5. "Ahora el PAMI empieza el trámite para poder pagarle a la Fundación". Eldia.com.ar. August 4, 2000.
  6. Krauss, Clifford (August 7, 2000). "Argentina Searches Its Soul Over a Suicide". The New York Times . Retrieved 15 June 2009.
  7. "Diana, nunca podrás imaginar cuánto te he amado". Gente.com.ar. Archived from the original on 2012-12-02. Retrieved 2013-10-10.
  8. "Golden Plate Awardees of the American Academy of Achievement". www.achievement.org. American Academy of Achievement.
  9. "René Favaloro's 96th Birthday". Google.com. 12 July 2019.