|Specialty|| Infectious disease |
Serratia infection refers to a disease caused by a species in the genus Serratia .
Serratia is a genus of Gram-negative, facultatively anaerobic, rod-shaped bacteria of the family Enterobacteriaceae. They are typically 1–5 μm in length and do not produce spores. The most common and pathogenic of the species in the genus, S. marcescens, is normally the only pathogen and usually causes nosocomial infections. However, rare strains of S. plymuthica, S. liquefaciens, S. rubidaea, and S. odoriferae have caused diseases through infection. S. marcescens is typically found in showers, toilet bowls, and around wetted tiles. Some members of this genus produce characteristic red pigment, prodigiosin, and can be distinguished from other members of the family Enterobacteriaceae by their unique production of three enzymes: DNase, lipase, and gelatinase.
The species involved is usually Serratia marcescens .
Serratia marcescens is a species of rod-shaped Gram-negative bacteria in the family Enterobacteriaceae. A human pathogen, S. marcescens is involved in hospital-acquired infections (HAIs), particularly catheter-associated bacteremia, urinary tract infections, and wound infections, and is responsible for 1.4% of HAI cases in the United States. It is commonly found in the respiratory and urinary tracts of hospitalized adults and in the gastrointestinal systems of children. Due to its abundant presence in the environment, and its preference for damp conditions, S. marcescens is commonly found growing in bathrooms, where it manifests as a pink, pink-orange, or orange discoloration and slimy film feeding off phosphorus-containing materials or fatty substances such as soap and shampoo residue.
It can cause nosocomial infections.
Panchlora nivea, the Cuban cockroach or green banana cockroach, is a small species of cockroach found in Cuba and the Caribbean, and along the Gulf Coast from Florida to Texas, and has been observed as far north as Summerville, South Carolina. It is found in subtropical or tropical climates.
Kanamycin A, often referred to simply as kanamycin, is an antibiotic used to treat severe bacterial infections and tuberculosis. It is not a first line treatment. It is used by mouth, injection into a vein, or injection into a muscle. Kanamycin is recommended for short-term use only, usually from 7 to 10 days. As with most antibiotics, it is ineffective in viral infections.
Flacherie is a disease of silkworms, caused by silkworms eating infected or contaminated mulberry leaves. Flacherie infected silkworms look weak and can die from this disease. Silkworm larvae that are about to die from Flacherie are a dark brown.
Coley's toxins is a mixture consisting of killed bacteria of species Streptococcus pyogenes and Serratia marcescens, named after William Coley, a surgical oncologist at the Hospital for Special Surgery who developed the mixture in the late 19th century as a treatment for cancer.
In biology and chemistry, gelatinase is a proteolytic enzyme that allows a living organism to hydrolyse gelatin into its sub-compounds that can cross the cell membrane and be used by the organism. It is not a pepsin.
Mezlocillin is a broad-spectrum penicillin antibiotic. It is active against both Gram-negative and some Gram-positive bacteria. Unlike most other extended spectrum penicillins, it is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending cholangitis.
Prodigiosin is the red pigment produced by many strains of the bacterium Serratia marcescens, other Gram-negative, gamma proteobacteria such as Vibrio psychroerythrus and Hahella chejuensis It is in a family of compounds termed "prodiginines", which are produced in some Gram-negative gamma proteobacteria, as well as select Gram-positive Actinobacteria. The name "prodigiosin" is derived from "prodigious".
Skeletal eroding band (SEB) is a disease of corals that appears as a black or dark gray band that slowly advances over corals, leaving a spotted region of dead coral in its wake. It is the most common disease of corals in the Indian and Pacific Oceans, and is also found in the Red Sea.
Proteases are in use, or have been proposed or tried, for a number of purposes related to medicine or surgery. Some preparations involving protease have undergone successful clinical trials and have regulatory authorization; and some further ones have shown apparently useful effects in experimental medical studies. Proteases have also been used by proponents of alternative therapies, or identified in materials of traditional or folk medicine. A serine protease of human origin, activated protein C, was produced in recombinant form and marketed as Drotrecogin alfa and licensed for intensive-care treatment of severe sepsis. It was voluntarily withdrawn by the manufacturer in 2011 after being shown to be ineffective.
White pox disease, first noted in 1996 on coral reefs near the Florida keys, is a coral disease affecting Elkhorn coral throughout the Caribbean. It causes irregular white patches or blotches on the coral that result from the loss of coral tissue. These patches distinguish white pox disease from white band disease which produces a distinctive white band where the coral skeleton has been denuded. The blotches caused by this disease are also clearly differentiated from coral bleaching and scars caused by coral-eating snails. It is very contagious, spreading to nearby coral.
In molecular biology, enzymes in the DNA/RNA non-specific endonuclease family of bacterial and eukaryotic endonucleases EC 3.1.30.- share the following characteristics: they act on both DNA and RNA, cleave double-stranded and single-stranded nucleic acids and require a divalent ion such as magnesium for their activity. A histidine has been shown to be essential for the activity of the Serratia marcescens nuclease. This residue is located in a conserved region which also contains an aspartic acid residue that could be implicated in the binding of the divalent ion.
Serratia marcescens nuclease is an enzyme. This enzyme catalyses the following chemical reaction
Serralysin is an enzyme. This enzyme catalyses the following chemical reaction
Dow Corning added silane (SiH4) to quaternary ammonia compounds, to improve the adhesion of QUATs to a variety of surfaces. In doing so, Dow invented a durable class of antimicrobials that are effective against a range of unicellular organisms.
Ceftolozane is a novel cephalosporin antibiotic, developed for the treatment of infections with gram-negative bacteria that have become resistant to conventional antibiotics. It was studied for urinary tract infections, intra-abdominal infections and ventilator-associated bacterial pneumonia. Ceftolozane is combined with the β-lactamase inhibitor tazobactam, which protects ceftolozane from degradation. Ceftolozane-tazobactam is indicated for the treatment of complicated urinary tract infections and complicated intra abdominal infections.
Operation Sea-Spray was a 1950 U.S. Navy secret experiment in which Serratia marcescens and Bacillus globigii bacteria were sprayed over the San Francisco Bay Area in California.
The HP1 Holin Family is a member of the Holin Superfamily II. Proteins in this family are typically found to contain two transmembrane segments (TMSs) and range between 70 to 80 amino acyl residues (aas) in length. A representative list of proteins belonging to the HP1 holin family can be found in the Transporter Classification Database.
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