Sulfolobus islandicus filamentous virus

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Sulfolobus islandicus filamentous virus
Virus classification OOjs UI icon edit-ltr.svg
(unranked): Virus
Realm: Adnaviria
Kingdom: Zilligvirae
Phylum: Taleaviricota
Class: Tokiviricetes
Order: Ligamenvirales
Family: Lipothrixviridae
Genus: Betalipothrixvirus
Species:
Sulfolobus islandicus filamentous virus

Sulfolobus islandicus filamentous virus (SIFV) is an archaeal virus, classified in the family Lipothrixviridae within the order Ligamenvirales . The virus infects hypethermophilic and acidophilic archaeon Sulfolobus islandicus . [1]

SIFV has a linear double-stranded DNA genome of 40,852 bp, which is the largest among characterized lipothrixviruses. The virions are enveloped filaments, nearly 2 micrometers in length. The nucleocapsid is formed from two paralogous major capsid proteins, which tightly wrap around the dsDNA genome; notably, dehydration of the genomic DNA by the major capsid proteins transforms the B-form DNA into A-form DNA. [2]

Life cycle

SIFV virions assemble inside the cell. Binding of the major capsid protein dimers to the linear dsDNA genome lead to the assembly of nucleocapsids, which are subsequently enveloped intracellularly through an unknown mechanism. [3] SIFV and probably other lipothrixviruses are lytic viruses. Virion release takes place through pyramidal portals, referred to as virus-associated pyramids (VAPs). [3] Unlike in the case of some other archaeal viruses (e.g., rudiviruses and turriviruses), the SIFV VAPs have a hexagonal base (i.e., constructed from six triangular facets). The VAPs can be as large as 220 nm at the base and are constructed from a single SIFV-encoded protein of 89 aa. [3] Expression of this protein in Escherichia coli leads to VAP formation in the inner bacterial membrane.[ citation needed ]

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<span class="mw-page-title-main">A-DNA</span> Potential conformation of DNA

A-DNA is one of the possible double helical structures which DNA can adopt. A-DNA is thought to be one of three biologically active double helical structures along with B-DNA and Z-DNA. It is a right-handed double helix fairly similar to the more common B-DNA form, but with a shorter, more compact helical structure whose base pairs are not perpendicular to the helix-axis as in B-DNA. It was discovered by Rosalind Franklin, who also named the A and B forms. She showed that DNA is driven into the A form when under dehydrating conditions. Such conditions are commonly used to form crystals, and many DNA crystal structures are in the A form. The same helical conformation occurs in double-stranded RNAs, and in DNA-RNA hybrid double helices.

Icerudivirus is a genus of viruses in the family Rudiviridae. These viruses are non-enveloped, stiff-rod-shaped viruses with linear dsDNA genomes, that infect hyperthermophilic archaea of the species Sulfolobus islandicus. There are three species in the genus.

<i>Lipothrixviridae</i> Family of viruses

Lipothrixviridae is a family of viruses in the order Ligamenvirales. Thermophilic archaea in the phylum Thermoproteota serve as natural hosts. There are 11 species in this family, assigned to 4 genera.

Fuselloviridae is a family of viruses. Sulfolobus species, specifically shibatae, solfataricus, and islandicus, serve as natural hosts. There are two genera and nine species in the family. The Fuselloviridae are ubiquitous in high-temperature (≥70 °C), acidic hot springs around the world.

<i>Halspiviridae</i> Family of viruses

Halspiviridae is a family of viruses that consists of a single genus, Salterprovirus, which consists of a single recognised species; Salterprovirus His1. This virus was isolated from hypersaline water in Australia and was able to be cultured on the halophilic archaeon Haloarcula hispanica. Like many other archaeoviruses, His1 has an approximately limoniform (lemon-shaped) virion.

<span class="mw-page-title-main">Bicaudaviridae</span> Family of viruses

Bicaudaviridae is a family of hyperthermophilic archaeal viruses. Members of the genus Acidianus serve as natural hosts. There is only one genus, Bicaudavirus, and one species, Acidianus two-tailed virus, in this family. However, Sulfolobus tengchongensis spindle-shaped viruses 1 and 2 are regarded to belong to this family also.

<i>Sulfolobus turreted icosahedral virus 1</i> Species of virus

Sulfolobus turreted icosahedral virus 1 is a species of virus that infects the archaeon Sulfolobus solfataricus.

<i>Clavaviridae</i> Family of viruses

Clavaviridae is a family of double-stranded viruses that infect archaea. This family was first described by the team led by D. Prangishvili in 2010. There is one genus in this family (Clavavirus). Within this genus, a single species has been described to date: Aeropyrum pernix bacilliform virus 1 (APBV1).

Ligamenvirales is an order of linear viruses that infect archaea of the phylum Thermoproteota and have double-stranded DNA genomes. The order was proposed by David Prangishvili and Mart Krupovic in 2012 and subsequently created by the International Committee on Taxonomy of Viruses (ICTV).

Yingchengvirus is a genus of double stranded DNA viruses that infect haloarchaea. The genus was previously named Betasphaerolipovirus.

Alphafusellovirus is a genus of viruses, in the family Fuselloviridae. Species in the genus Sulfolobus serve as natural hosts. There are seven species in this genus.

Tristromaviridae is a family of viruses. Archaea of the genera Thermoproteus and Pyrobaculum serve as natural hosts. Tristromaviridae is the sole family in the order Primavirales. There are two genera and three species in the family.

Betalipothrixvirus is a genus of viruses in the family Lipothrixviridae. Archaea serve as natural hosts. The genus contains six species.

Spiraviridae is a family of incertae sedis viruses that replicate in hyperthermophilic archaea of the genus Aeropyrum, specifically Aeropyrum pernix. The family contains one genus, Alphaspiravirus, which contains one species, Aeropyrum coil-shaped virus. The virions of ACV are non-enveloped and in the shape of hollow cylinders that are formed by a coiling fiber that consists of two intertwining halves of the circular DNA strand inside a capsid. An appendage protrudes from each end of the cylindrical virion. The viral genome is ssDNA(+) and encodes for significantly more genes than other known ssDNA viruses. ACV is also unique in that it appears to lack its own enzymes to aid replication, instead likely using the host cell's replisomes. ACV has no known relation to any other archaea-infecting viruses, but it does share its coil-like morphology with some other archaeal viruses, suggesting that such viruses may be an ancient lineage that only infect archaea.

<span class="mw-page-title-main">Sulfolobus tengchongensis spindle-shaped virus</span> Species of virus

Sulfolobus tengchongensis spindle-shaped virus 1 (STSV1) is a DNA virus of the family Bicaudaviridae. It infects the hyperthermophilic archaeon Sulfolobus tengchongensis which can be found in the volcanic area of Tengchong, Baoshan City, in western Yunnan province, People's Republic of China.

Sulfolobus islandicus rod-shaped virus 2, also referred to as SIRV2, is an archaeal virus whose only known host is the archaeon Sulfolobus islandicus. This virus belongs to the family Rudiviridae. Like other viruses in the family, it is common in geothermal environments.

In virology, realm is the highest taxonomic rank established for viruses by the International Committee on Taxonomy of Viruses (ICTV), which oversees virus taxonomy. Six virus realms are recognized and united by specific highly conserved traits:

<span class="mw-page-title-main">Archaeal virus</span>

An archaeal virus is a virus that infects and replicates in archaea, a domain of unicellular, prokaryotic organisms. Archaeal viruses, like their hosts, are found worldwide, including in extreme environments inhospitable to most life such as acidic hot springs, highly saline bodies of water, and at the bottom of the ocean. They have been also found in the human body. The first known archaeal virus was described in 1974 and since then, a large diversity of archaeal viruses have been discovered, many possessing unique characteristics not found in other viruses. Little is known about their biological processes, such as how they replicate, but they are believed to have many independent origins, some of which likely predate the last archaeal common ancestor (LACA).

<i>Portogloboviridae</i> Family of viruses

Portogloboviridae is a family of dsDNA viruses that infect archaea. It is a proposed family of the realm Varidnaviria, but ICTV officially puts it as incertae sedis virus. Viruses in the family are related to Helvetiavirae. The capsid proteins of these viruses and their characteristics are of evolutionary importance for the origin of the other Varidnaviria viruses since they seem to retain primordial characters.

<i>Adnaviria</i> Realm of viruses

Adnaviria is a realm of viruses that includes archaeal viruses that have a filamentous virion and a linear, double-stranded DNA genome. The genome exists in A-form (A-DNA) and encodes a dimeric major capsid protein (MCP) that contains the SIRV2 fold, a type of alpha-helix bundle containing four helices. The virion consists of the genome encased in capsid proteins to form a helical nucleoprotein complex. For some viruses, this helix is surrounded by a lipid membrane called an envelope. Some contain an additional protein layer between the nucleoprotein helix and the envelope. Complete virions are long and thin and may be flexible or a stiff like a rod.

References

  1. Arnold, Hans Peter; Zillig, Wolfram; Ziese, Ulrike; et al. (2000). "A novel lipothrixvirus, SIFV, of the extremely thermophilic crenarchaeon Sulfolobus". Virology. 267 (2): 252–266. doi: 10.1006/viro.1999.0105 . PMID   10662621.
  2. Wang, F; Baquero, DP; Beltran, LC; Su, Z; Osinski, T; Zheng, W; Prangishvili, D; Krupovic, M; Egelman, EH (2020). "Structures of filamentous viruses infecting hyperthermophilic archaea explain DNA stabilization in extreme environments". Proceedings of the National Academy of Sciences of the United States of America. 117 (33): 19643–19652. Bibcode:2020PNAS..11719643W. doi: 10.1073/pnas.2011125117 . PMC   7443925 . PMID   32759221.
  3. 1 2 3 Baquero, DP; Gazi, AD; Sachse, M; Liu, J; Schmitt, C; Moya-Nilges, M; Schouten, S; Prangishvili, D; Krupovic, M (2021). "A filamentous archaeal virus is enveloped inside the cell and released through pyramidal portals". Proceedings of the National Academy of Sciences of the United States of America. 118 (32): e2105540118. Bibcode:2021PNAS..11805540B. doi: 10.1073/pnas.2105540118 . PMC   8364153 . PMID   34341107.