|Thuja standishii foliage and cones |
upper side left, under side right
Thuja standishii (Japanese thuja; nezuko, kurobe) is a species of thuja, an evergreen coniferous tree in the cypress family Cupressaceae. It is native to southern Japan, where it occurs on the islands of Honshū and Shikoku. It is a medium-sized tree, reaching 20–35 m tall and with a trunk up to 1 m diameter.
The foliage forms in flat sprays with scale-like leaves 2–4 mm long, matte green above, and with narrow white stomatal bands below. The cones are oval, yellow-green ripening red-brown, 6–12 mm long and 4–5 mm broad (opening to 8 mm broad), with 6–10 overlapping scales.
It is an important timber tree in Japan, grown in forestry plantations for its durable, waterproof, attractively scented wood.
There is some evidence that extracts of T. standishii have biological activity. It contains a compound called standishinal which has shown relatively potent effects on the enzyme aromatase. It acts as an inhbitor, thus decreasing the synthesis of Estradiol in the human body. This compound has been used in research and derivatives of it have shown even stronger inhibition of Aromatase.
Thuja is a genus of coniferous trees in the Cupressaceae. There are five species in the genus, two native to North America and three native to eastern Asia. The genus is monophyletic and sister to Thujopsis. Members are commonly known as arborvitaes, thujas or cedars.
Cupressaceae is a conifer family, the cypress family, with worldwide distribution. The family includes 27–30 genera, which include the junipers and redwoods, with about 130–140 species in total. They are monoecious, subdioecious or (rarely) dioecious trees and shrubs up to 116 m (381 ft) tall. The bark of mature trees is commonly orange- to red- brown and of stringy texture, often flaking or peeling in vertical strips, but smooth, scaly or hard and square-cracked in some species.
Thuja plicata, commonly called western red cedar or Pacific red cedar, giant arborvitae or western arborvitae, giant cedar, or shinglewood, is a species of Thuja, an evergreen coniferous tree in the cypress family Cupressaceae native to western North America. It is not a true cedar of the genus Cedrus.
Thuja occidentalis, also known as northern white cedar, eastern white cedar, or arborvitae, is an evergreen coniferous tree, in the cypress family Cupressaceae, which is native to eastern Canada and much of the northcentral and northeastern United States. It is widely cultivated as an ornamental plant.
Platycladus is a monotypic genus of evergreen coniferous tree in the cypress family Cupressaceae, containing only one species, Platycladus orientalis, also known as Chinese thuja, Oriental arborvitae, Chinese arborvitae, biota or Oriental thuja. It is native to northeastern parts of East Asia and North Asia, but is also now naturalised as an introduced species in other regions of the Asian continent.
Thujopsis is a genus of conifers in the cypress family (Cupressaceae), the sole member of which is Thujopsis dolabrata. It is endemic to Japan, where it is named asunaro (あすなろ). It is similar to the closely related genus Thuja (arborvitae), differing in the broader, thicker leaves and thick cones. It is also called hiba, false arborvitae, or hiba arborvitae.
Chamaecyparis obtusa is a species of cypress native to central Japan in East Asia, and widely cultivated in the temperate northern hemisphere for its high quality timber and ornamental qualities, with many cultivars commercially available.
Aromatase inhibitors (AIs) are a class of drugs used in the treatment of breast cancer in postmenopausal women and gynecomastia in men. They may also be used off-label to reduce estrogen conversion when using external testosterone. They may also be used for chemoprevention in high risk women.
Picea martinezii, the Martinez spruce, is a medium-sized evergreen tree growing to 25–35 m tall, and with a trunk diameter of up to 1 m. It is native to northeast Mexico, where it occurs at two localities in the Sierra Madre Oriental mountains in Nuevo León. It grows at moderate altitudes from 2150–2600 m, growing along streamsides in mountain valleys, where moisture levels in the soil are greater than the otherwise low rainfall in the area would suggest.
Tetraclinis is a genus of evergreen coniferous trees in the cypress family Cupressaceae, containing only one species, Tetraclinis articulata, also known as Thuja articulata, sandarac, sandarac tree or Barbary thuja, endemic to the western Mediterranean region. It is native to northwestern Africa in the Atlas Mountains of Morocco, Algeria, and Tunisia, with two small outlying populations on Malta, and near Cartagena in southeast Spain. It grows at relatively low altitudes in a hot, dry subtropical Mediterranean climate.
Juniperus drupacea, the Syrian juniper, is a species of juniper native to the eastern Mediterranean region from southern Greece, southern Turkey, western Syria, and Lebanon, growing on rocky sites from 800–1700 m altitude.
Thuja sutchuenensis, the Sichuan thuja, is a species of Thuja, an evergreen coniferous tree in the cypress family Cupressaceae. It is native to China, where it is an endangered local endemic in Chengkou County, on the southern slope of the Daba Mountains.
Tropolone is an organic compound with the formula C7H5(OH)O. It is a pale yellow solid that is soluble in organic solvents. The compound has been of interest to research chemists because of its unusual electronic structure and its role as a ligand precursor. Although not usually prepared from tropone, it can be viewed as its derivative with a hydroxyl group in the 2-position.
Abies nephrolepis, commonly known as Khingan fir, is a species of fir native to northeastern China, North Korea, South Korea, and southeastern Russia.
Thuja koraiensis, also called Korean arborvitae, is a species of Thuja, native to Korea and the extreme northeast of China (Changbaishan). Its current status is poorly known; the small population in China is protected in the Changbaishan Nature Reserve, as is the small population in Soraksan Nature Reserve in northern South Korea, but most of the species' range in North Korea is unprotected and threatened by habitat loss.
1,4,6-Androstatriene-3,17-dione (ATD) is a potent irreversible aromatase inhibitor that inhibits estrogen biosynthesis by permanently binding and inactivating aromatase in adipose and peripheral tissue. It is used to control estrogen synthesis.
Thujaplicins are a series of tropolone-related chemical substances that have been isolated from the hardwoods of the trees of Cupressaceae family. These compounds are known for their antibacterial, antifungal and antioxidant properties. They were the first natural tropolones to be made synthetically.
Chalconoids Greek: χαλκός khalkós, "copper", due to its color), also known as chalcones, are natural phenols related to chalcone. They form the central core for a variety of important biological compounds.
Paeoniflorin is a chemical compound which is one of the major constituents of an herbal medicine derived from Paeonia lactiflora. It can also be isolated from the fresh water fern Salvinia molesta.
Steroidal aromatase inhibitors are a class of drugs that are mostly used for treating breast cancer in postmenopausal women. High levels of estrogen in breast tissue increases the risk of developing breast cancer and the enzyme aromatase is considered to be a good therapeutic target when treating breast cancer due to it being involved in the final step of estrogen biosynthetic pathway and also its inhibitation will not affect production of other steroids. Aromatase Inhibitors are classified into two categories based on their structure, nonsteroidal and steroidal; the latter resemble the structure of androstenedione. Steroidal aromatase inhibitors irreversibly inhibit the enzyme by binding covalently to the binding site of aromatase so the substrate can't access it.
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