Snowboards are boards where both feet are secured to the same board, which are wider than skis, with the ability to glide on snow. Snowboards widths are between 6 and 12 inches or 15 to 30 centimeters. Snowboards are differentiated from monoskis by the stance of the user. In monoskiing, the user stands with feet inline with direction of travel, whereas in snowboarding, users stand with feet transverse to the longitude of the board. Users of such equipment may be referred to as snowboarders. Commercial snowboards generally require extra equipment such as bindings and special boots which help secure both feet of a snowboarder, who generally rides in an upright position. These types of boards are commonly used by people at ski hills or resorts for leisure, entertainment, and competitive purposes in the activity called snowboarding.
Hosiery, also referred to as legwear, describes garments worn directly on the feet and legs. The term originated as the collective term for products of which a maker or seller is termed a hosier; and those products are also known generically as hose. The term is also used for all types of knitted fabric, and its thickness and weight is defined by denier or opacity. Lower denier measurements of 5 to 15 describe a hose which may be sheer in appearance, whereas styles of 40 and above are dense, with little to no light able to come through on 100 denier items.
Foot binding was the custom of applying tight binding to the feet of young girls to modify the shape and size of their feet. It was practiced in China from the Tang dynasty until the early 20th century, and bound feet were considered a status symbol as well as a mark of beauty. Foot binding was a painful practice and significantly limited the mobility of women, resulting in lifelong disabilities for most of its subjects. Feet altered by binding were called lotus feet.
A cofactor is a non-protein chemical compound or metallic ion that is required for an enzyme's activity. Cofactors can be considered "helper molecules" that assist in biochemical transformations. The rates at which these happen are characterized by enzyme kinetics.
Shibori is a Japanese manual resist dyeing technique, which produces patterns on fabric.
PLATO is a suite of programs for electronic structure calculations. It receives its name from the choice of basis set used to expand the electronic wavefunctions.
Nuclear binding energy is the minimum energy that would be required to disassemble the nucleus of an atom into its component parts. These component parts are neutrons and protons, which are collectively called nucleons. The binding is always a positive number, as we need to spend energy in moving these nucleons, attracted to each other by the strong nuclear force, away from each other. The mass of an atomic nucleus is less than the sum of the individual masses of the free constituent protons and neutrons, according to Einstein's equation E=mc2. This 'missing mass' is known as the mass defect, and represents the energy that was released when the nucleus was formed.
Iron-56 (56Fe) is the most common isotope of iron. About 91.754% of all iron is iron-56.
An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. They are also used in pesticides. Not all molecules that bind to enzymes are inhibitors; enzyme activators bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
Breast binding is the act of flattening breasts by the use of constrictive materials. The term also refers to the material used in this act. Common binding materials include cloth strips, elastic or non-elastic bandages, purpose-built undergarments and shirts layered from tight to loose. The act of breast binding is common for trans men, but is also done by androgynous, genderqueer and gender fluid people, as well as crossdressers, cosplayers, and performers. In a general sense; women may also use binders as alternatives to bras or as a practice of propriety.
Nickel-62 is an isotope of nickel having 28 protons and 34 neutrons.
Clostridium enterotoxins are toxins produced by Clostridium species.
A dihydrofolate reductase inhibitor is a molecule that inhibits the function of dihydrofolate reductase, and is a type of antifolate.
JWH-198 is a drug from the aminoalkylindole family which acts as a cannabinoid receptor agonist. It was invented by the pharmaceutical company Sanofi-Winthrop in the early 1990s. JWH-198 has a binding affinity at the CB1 receptor of 10nM, binding around four times more tightly than the parent compound JWH-200, which has no substitution on the naphthoyl ring. It has been used mainly in molecular modelling of the cannabinoid receptors.
JWH-193 is a drug from the aminoalkylindole family which acts as a cannabinoid receptor agonist. It was invented by the pharmaceutical company Sanofi-Winthrop in the early 1990s. JWH-193 has a binding affinity at the CB1 receptor of 6nM, binding around seven times more tightly than the parent compound JWH-200, though with closer to twice the potency of JWH-200 in activity tests. A structural isomer of JWH-193 with the methyl group on the indole ring instead of the naphthoyl ring, was also found to be of similarly increased potency over JWH-200.
As a type of binding knot, the jamming knot is good for constricting a bundle of objects such as sticks or brush. It is basically a taut-line hitch but the initial two wraps are on the outside of the working line rather than on the inside, and finished off with one wrap on the inside. Thus the knot holds tension towards the inside of the loop rather than the standing end of the rope as with the taut-line – turning a tension knot into a constricting knot. After the knot is tied, the knot is held with one hand, the standing end is pulled tight, and the knot should hold fast. This knot, as with the taut-line, can be difficult or impossible to tie on slick or particularly stiff rope.
ADSB-FUB-187 is an indazole-based synthetic cannabinoid. It is a potent agonist of the CB1 receptor with a binding affinity of Ki = 0.09 nM and an EC50 of 1.09 nM. It was originally developed by Pfizer in 2009, being example 187 from patent WO 2009/106982. While it is the most tightly binding compound from this patent in terms of Ki, it is not the most potent compound at producing a CB1 mediated pharmacological effect, with at least 17 other compounds from the patent having lower EC50 values.
2-Bromomescaline (2-Br-M) is a derivative of the phenethylamine hallucinogen mescaline which has an unusual 2-bromo substitution. It is an agonist for serotonin receptors, with a binding affinity of 215 nM at 5-HT1A, 513 nM at 5-HT2A and 379 nM at 5-HT2C, so while it is around ten times more tightly binding than mescaline at 5-HT1A and 5-HT2A receptors, it is over twenty times more potent at 5-HT2C.
