Tom Connors (research scientist)

Last updated

Professor Thomas Anthony Connors (18 December 1934 4 February 2002) was a British cancer research scientist. [1]

Connors was for 40 years involved in the development of anti-cancer drugs including cis-platinum and its derivative, carbo-platin, [2] two effective anti-cancer agents. Connors' initial research was under the auspices of mentor and friend Professor Walter Ross at the Chester Beatty Institute where he gained his Doctorate in 1960. [3] In 1976 Connors' career expanded into the field of toxicology and he was appointed Director of the Medical Research Council's toxicology unit. Connors also sat on committees including the Cancer Research Campaign. He formed the Phase I/II Drug Development Committee during this period. Connors also advised overseas institutes and their governments. and was a special advisor to President Gerald Ford. On retirement in 1994 Connors was appointed Honorary Professor at the School of Pharmacy, University of London. Connors was awarded many honours including honorary degrees from several universities, Including Aston (1997) [4] and Dublin Trinity in 2001. [5] He has a research unit named after him at Bradford University. [6]

Tom Connors was an alumnus of Wimbledon College, to which he won a scholarship to study in the 1940s/50's. As well as proving to be an adept academic, he represented the school at rugby where he played wing three-quarter and went on to play many times for the Old Wimbledonians rugby club. He also represented the school and London schools at athletics, being at the time one of the fastest boys over 100 yards in the country. Tom was also an active member of the Old Wimbledonians Association.

Related Research Articles

Frederick Gowland Hopkins

Sir Frederick Gowland Hopkins was an English biochemist who was awarded the Nobel Prize in Physiology or Medicine in 1929, with Christiaan Eijkman, for the discovery of vitamins, even though Casimir Funk, a Polish biochemist, is widely credited with discovering vitamins. He also discovered the amino acid tryptophan, in 1901. He was President of the Royal Society from 1930 to 1935.

The Institute of Cancer Research is a public research institute and a constituent college of the University of London in London, United Kingdom, specialising in oncology. It was founded in 1909 as a research department of the Royal Marsden Hospital and joined the University of London in 2003. It has been responsible for a number of breakthrough discoveries, including that the basic cause of cancer is damage to DNA.

Bruce Ames American biochemist

Bruce Nathan Ames is an American biochemist. He is a professor of Biochemistry and Molecular Biology Emeritus at the University of California, Berkeley, and was a senior scientist at Children's Hospital Oakland Research Institute (CHORI). He is the inventor of the Ames test, a system for easily and cheaply testing the mutagenicity of compounds.

William Paul Colton, known as Paul Colton, is the Church of Ireland's Bishop of Cork, Cloyne and Ross. He is perhaps best known for being the bishop who officiated at the wedding of footballer David Beckham and Spice Girl Victoria Adams on 4 July 1999 at the medieval Luttrellstown Castle on the outskirts of Dublin.

Andrew Jess Dannenberg is a U.S. physician and researcher, currently Henry R. Erle, M.D. - Roberts Family Professor of Medicine at Weill Medical College/M.D. Anderson Cancer Center. He additionally holds the positions of Professor of Medicine in Cardiothoracic surgery and Director of Cancer Prevention. He received a B.S. from Tufts University in 1978 and an M.D. from Washington University School of Medicine in 1982.

Herbert Edmund Carter was an American biochemist and educator. He grew up in central Indiana and received his bachelor's degree from DePauw University. He received a Ph.D. in 1934 in organic chemistry from the University of Illinois.

Ronald T. Raines

Ronald T. Raines is an American chemical biologist. He is the Roger and Georges Firmenich Professor of Natural Products Chemistry at the Massachusetts Institute of Technology. He is known for using ideas and methods of physical organic chemistry to solve important problems in biology.

Professor Karen Heather Vousden, CBE, FRS, FRSE, FMedSci is a British medical researcher. She is known for her work on the tumour suppressor protein, p53, and in particular her discovery of the important regulatory role of Mdm2, an attractive target for anti-cancer agents. From 2003 to 2016, she was the director of the Cancer Research UK Beatson Institute in Glasgow, UK, moving back to London in 2016 to take up the role of Chief Scientist at CRUK and Group Leader at the Francis Crick Institute.


Dichlorotetrakis(dimethyl sulfoxide) ruthenium(II) describes coordination compounds with the formula RuCl2(dmso)4, where DMSO is dimethylsulfoxide. Both cis and trans isomers are known, but the cis isomer is more common. The cis isomer (pictured) is a yellow, air-stable solid that is soluble in some organic solvents. These compounds have attracted attention as possible anti-cancer drugs.

Hani Gabra

Hani Gabra PhD FRCPE FRCP is a British oncologist and Professor of Medical Oncology at Imperial College London. He concurrently holds the position of Chief Medical Officer at BerGenBio in Oxford, UK.

Ian Robertson is a Scottish neuroscientist and clinical psychologist, and Professor of Psychology at Trinity College Dublin.

Yinsheng Wang is a Professor of Chemistry and the Director for the ETOX Graduate Program at the University of California Riverside. His current research involves the use of a multi-pronged approach encompassing mass spectrometry, synthetic chemistry, and molecular biology, for understanding the biological consequences of DNA damage and the molecular mechanisms of actions of anti-cancer drugs and environmental toxicants.

Judith Ann Clements is an Australian academic and educator, specializing in Kallikrein proteases in prostate and ovarian cancers. Clements is the Scientific Director at the Australian Prostate Cancer Research Centre – Queensland and was head of the Cancer Research Program at the Institute of Health and Biomedical Innovation (IHBI) of Queensland University of Technology at the Translational Research Institute (Australia) from 1997–2014.

William Hamish Beith Wallace is a consultant Paediatric Oncologist at the Royal Hospital for Sick Children, Edinburgh. Since 2015, Wallace has been National Clinical Director of the Managed Service Network for Children and Young People with Cancer in Scotland.

Albert P. Li is president and CEO of In Vitro ADMET Laboratories (IVAL), Columbia, Maryland, and Malden, Massachusetts. For the past three decades, Li has devoted his scientific career to the advancement of scientific concepts and technologies to accurately predict human drug properties. His research is focused on the development and application of human-based in vitro experimental systems in drug discovery and development. He is a pioneer in the isolation, cryopreservation, and culturing of human hepatocytes and their application in the evaluation of drug metabolism, drug-drug interactions, and drug toxicity.

Gareth Jenkins is a professor of molecular carcinogenesis at Swansea University Medical School. Based in the Institute of Life Science, his interests include the study of DNA mutation induction and the role of DNA mutations as diagnostic biomarkers for cancer. He is also director of research of the medical school and a “research leader” for Health and Care Research Wales. Jenkins' research gained much recognition during 2016 when his revolutionary cancer-detecting blood test was widely covered in the British press.

Ruth Plummer FMedSci is a Professor of Experimental Cancer Medicine at Newcastle University and an oncologist specialising in treating patients with melanoma. Based in Newcastle, she directs the Sir Bobby Robson Cancer Trials Research Centre, set up by the Sir Bobby Robson Foundation to run early-stage clinical trials.v Plummer and the Newcastle team won a 2010 Translational Cancer Research Prize from Cancer Research UK for work using rucaparib to treat ovarian cancer.. Plummer was elected as a fellow of the UK's Academy of Medical Sciences in 2018.

Celine J. Marmion is a Professor of Chemistry at the Royal College of Surgeons in Ireland and President of the Institute of Chemistry of Ireland. She is a Fellow of the Royal Society of Chemistry and the Institute of Chemistry of Ireland. Marmion is involved with the design of new chemotherapeutic drugs.

Luke Drury (astrophysicist) Irish mathematician and astrophysicist

Luke O’Connor Drury is an Irish mathematician and astrophysicist at the Dublin Institute for Advanced Studies (DIAS) with research interests in plasma physics, particle acceleration, gas dynamics, shock waves, and cosmic rays. He was President of the Royal Irish Academy from 2011 to 2014.


  1. "Professor Tom Connors and the development of novel cancer therapies by the Phase I/II Clinical Trials Committee of Cancer Research UK", British Journal of Cancer (2003) 89, 437–454. doi:10.1038/sj.bjc.6601106 Published online 29 July 2003
  2. Connors TA, et al. (1972). "New platinum complexes with anti-tumour activity". Chem Biol Interact. 5 (6): 415–24. doi:10.1016/0009-2797(72)90078-6. PMID   4652593.
  3. Connors TA, Jones M, Ross WC, Braddock PD, Khokhar AR, Tobe ML (1972). "New platinum complexes with anti-tumour activity". Chem Biol Interact. 5 (6): 415–24. doi:10.1016/0009-2797(72)90078-6. PMID   4652593.
  4. "Honorary graduates of Aston University". Archived from the original on 22 July 2015. Retrieved 4 August 2015.
  5. Trinity College Dublin (2 July 2015). "Recipients - Honorary Degrees - Registrar : Trinity College Dublin, the University of Dublin, Ireland" . Retrieved 4 August 2015.
  6. Bradford University