|Maintained by SCDOT|
|Length||140.600 mi (226.274 km)|
|Existed||1927[ citation needed ]–present|
|South end||US 1 / US 25 / US 78 / US 278 / SR 10 / SR 121 at the Georgia state line near North Augusta|
|North end||US 25 at the North Carolina line near Travelers Rest|
|Counties||Aiken, Edgefield, Greenwood, Laurens, Greenville|
U.S. Route 25 (US 25) is a 140.600-mile (226.274 km) U.S. Highway that travels from Brunswick, Georgia to the Kentucky–Ohio state line, where Covington, Kentucky meets Cincinnati, Ohio at the Ohio River. In the U.S. state of South Carolina, it travels south to north in the western part of the state, serving the northern part of the Augusta metropolitan area, Greenwood, and Greenville on its path from North Augusta to North Carolina in the Saluda Mountains, near Travelers Rest.
US 25, from I-85 to the North Carolina state line, is part of the Appalachian Development Highway System (ADHS), which is part of Appalachian Regional Commission (ARC). Of the 30.7-mile (49.4 km) section of US 25, only 22.9-mile (36.9 km) was authorized for ADHS funding. In the 2013 fiscal year, South Carolina completed Corridor W and also became the first state to complete its entire ADHS miles among all 13 Appalachian states. The entire section of US 25 along Corridor W boasts a four-to-six-lane limited-access road, with interchanges at major intersections.
Established in 1928 as an original U.S. Highway, it was assigned to the entirety of SC 21, which was removed the same year. Traveling closely as it does today, it went from North Augusta to Travelers Rest, connecting the cities and towns of Edgefield, Greenwood, Ware Shoals, and Greenville.
In 1937, US 25 was rerouted in Greenville, moving onto College Avenue from Main Street to Buncombe Street. By 1961, US 25 was moved onto a new bypass east of North Augusta, leaving US 25 Bus. In 1963, Ware Shoals was bypassed east, leaving another US 25 Bus. In 1964, US 25 was rerouted onto new primary routing east of Travelers Rest, leaving Main Street to US 276 and Poinsett Highway downgraded to secondary (today now an unsigned US 25 Conn).
By 1969, US 25 was rerouted onto a western bypass of Greenville, replacing SC 250; the old alignment was replaced by US 25 Bus. Also in the same year, US 25 was given its current eastern bypass around Greenwood, leaving US 25 Bus along its old alignment along Main and Montague Streets. In 1973, US 25 was rerouted in northern Greenville County onto new modern ascent along the Saluda Mountains; the old route was downgraded to secondary (Old Highway 25 - S-23-969).
|Location||North Augusta–Travelers Rest|
South Carolina Highway 21 (SC 21) was an original state highway that was established on a path from the Georgia state line at North Augusta to the North Carolina state line at Caesars Head State Park, northwest of Cleveland.
In about 1925, the portion north of Travelers Rest was shifted to the east, replacing the path of SC 29, with its northern terminus at the North Carolina state line at a point north-northeast of Cleveland. Its former path became SC 211 and is now part of US 276.
By the end of 1926, the path of the highway between Edgefield and Kirksey was re-routed, replacing part of SC 43.
In 1928, SC 21 was decommissioned, with its path replaced by US 25.
US 1 south / US 25 south / US 78 west / US 278 west / SR 10 west / SR 121 south (Gordon Highway) – Augusta
|Continuation from Georgia|
|South Carolina–Georgia state line|
|5th Street Bridge / River North Drive||Interchange|
US 1 north / US 78 / US 278 east – Aiken
|Northern end of US 1 and US 78/US 278 concurrencies|
Buena Vista Avenue east (SC 125 Conn. east) to US 78 west / US 1 south – Augusta
|Southern end of SC 125 Conn. concurrency|
|0.970||1.561||Buena Vista Avenue west (SC 125 Conn. west)||Northern end of SC 125 Conn. concurrency|
SC 125 / SC 230 north (Atomic Road) – North Augusta, Savannah River Site
SC 125 Truck begins
|Southern end of SC 125 Truck/SC 230 concurrencies; southern terminus of SC 125 Truck and SC 230|
SC 230 north (Martintown Road / SC 125 Truck north) – Lake Thurmond
|Northern end of SC 125 Truck/SC 230 concurrency|
US 25 Bus. south (Georgia Avenue) – Augusta
|Northern terminus of US 25 Bus.|
SC 126 east (Belvedere Clearwater Road) – Clearwater
|Western terminus of SC 126|
To I-520 (US 25 Conn.)
|Western terminus of US 25 Conn.; I-520 exit 22|
|7.020||11.298||I-20 – Columbia, Atlanta||I-20 exit 5|
SC 19 south / SC 121 north – Aiken, Johnston
|Northern end of SC 121 concurrency; northern terminus of SC 19|
SC 23 east (Columbia Road) – Johnston
|Southern end of SC 23 concurrency|
SC 23 west (Main Street) – Modoc
|Northern end of SC 23 concurrency|
Meeting Street Road north to SC 430 – Saluda, Johnston
|Southern terminus of Meeting Street Road|
SC 23 Truck north (Crest Road / SC 430 Conn. east) to SC 430 – Johnston, Saluda
|Southern end of SC 23 Truck concurrency; western terminus of SC 430 Conn.|
SC 283 west – Plum Branch
|Eastern terminus of SC 283|
|||38.880||62.571||US 378 – Saluda, McCormick|
| McCormick–Greenwood county line||No major junctions|
US 178 east – Columbia
|Southern end of US 178 concurrency|
SC 67 south (Callison Highway) – Callison
|Northern terminus of SC 67|
SC 225 north – Abbeville
|Southern terminus of SC 225|
US 221 south / US 25 Bus. north / US 178 Bus. west – McCormick
|Southern end of US 221 concurrency|
|58.030||93.390||SC 34 (Ninety Six Highway) – Ninety Six||Interchange|
US 221 north / SC 72 east / SC 72 Bus. west (Reynolds Avenue) – Laurens, Clinton
|Northern end of US 221 concurrency; southern end of SC 72 concurrency|
|63.160||101.646||SC 254 (Cokesbury Road) – Cokesbury|
US 25 Bus. south / US 178 Bus. east / SC 72 west – Abbeville
|Northern end of SC 72 concurrency|
US 178 west (Moorefield Street) to SC 185 – Anderson, Due West
|Northern end of US 178 concurrency|
|||70.600||113.620||SC 246 (Emerson Street) – Cokesbury, Hodges|
SC 254 south (Cokesbury Road) – Cokesbury
|Northern terminus of SC 254|
US 25 Bus. north (Greenwood Avenue) – Ware Shoals
|Southern terminus of US 25 Bus.|
US 25 Bus. south / SC 252 – Ware Shoals, Laurens
|Northern terminus of US 25 Bus.|
US 76 east – Laurens
|Southern end of US 76 concurrency|
US 76 west (Princeton Highway) – Honea Path
|Northern end of US 76 concurrency|
SC 247 south (Cooley Bridge Road) – Belton
|Northern terminus of SC 247|
SC 8 west (Pelzer Highway) / SC 418 east (Old Hundred Road) – Pelzer, Fountain Inn
|Eastern terminus of SC 8; western terminus of SC 418|
SC 86 west (Bessie Road) – Piedmont
|Eastern terminus of SC 86|
I-185 Toll (Southern Connector) – Spartanburg, Columbia, Greenville, Atlanta
|I-185 exit 7|
SC 291 north (Augusta Highway) – Greenville
|Southern terminus of SC 291|
|I-85 – Spartanburg, Atlanta||I-85 exit 44|
SC 20 (Piedmont Highway) to I-185 north / US 29 north – Greenville, Piedmont
|I-185 exit 16 southbound|
I-185 south / US 29 south – Atlanta
|I-185 exit 15 northbound|
|||112.440||180.955||SC 81 (Anderson Road) – Greenville, Anderson|
|||113.790||183.127||US 123 (New Easley Highway) – Greenville, Easley, Clemson|
|SC 124 (Old Easley Highway) – Greenville, Easley|
|||115.210||185.413||SC 253 (Blue Ridge Drive) – Greer, Easley|
|||118.200||190.224||SC 183 (Farrs Bridge Road) – Greenville, Pickens|
US 276 east (Poinsett Highway) – Greenville
|Southern end of US 276 concurrency; no northbound exit, southbound left exit|
US 276 west (Main Street) – Cleveland, Caesars Head, Brevard
|Northern end of US 276 concurrency; northbound left exit|
|124.840||200.911||Poinsett Highway south – Travelers Rest||Northern terminus of US 25 Conn. and Poinsett Highway; eastern terminus of US 276 Conn.|
SC 290 east (Locust Hill Road) – Greer
|Western terminus of SC 290|
SC 414 west (Bates Crossing Road)
|Southern end of SC 414 concurrency|
SC 414 east – Tigerville
|Northern end of SC 414 concurrency; to North Greenville University and Campbell's Covered Bridge|
|||133.590||214.992||SC 11 (Cherokee Foothills Scenic Highway) – Cleveland, Gowensville, Marietta|
|||134.240||216.038||Old Highway 25 north – Camp Old Indian, Saluda, Poinsett Bridge Heritage Preserve||Southern terminus of Old Highway 25; former US 25 north; to Poinsett Bridge|
US 25 north – Hendersonville, Asheville
|Continuation into North Carolina|
|1.000 mi = 1.609 km; 1.000 km = 0.621 mi|
South Carolina Highway 5 (SC 5) is a 51.719-mile (83.234 km) primary state highway in the U.S. state of South Carolina. The highway, signed as north-south, travels in a northwest-southeast direction connecting the cities of Rock Hill, York and Blacksburg.
South Carolina Highway 421 (SC 421) is a 10.360-mile (16.673 km) state highway in the U.S. state of South Carolina. It is an alternate route to U.S. Route 1 (US 1) and US 78 between North Augusta and Aiken.
U.S. Route 278 (US 278) is a 146.130-mile (235.173 km) east–west United States highway that traverses through the South Carolina Lowcountry, from North Augusta to Hilton Head Island.
U.S. Route 78 (US 78) is a 142.207-mile (228.860 km) U.S. highway that travels from Memphis, Tennessee to Charleston, South Carolina. In the U.S. state of South Carolina, it travels from the Savannah River at North Augusta to its eastern terminus in Charleston; connecting the cities of Aiken, Summerville, and North Charleston.
U.S. Route 52 (US 52) is a 159.960-mile (257.431 km) north–south U.S. Highway that travels from Charleston to the North Carolina state line near Cheraw. It serves as a strategic highway through the central part of the state. Though an even-numbered U.S. Highway, which are typically signed east–west, it is signed north–south in South Carolina. In some other states along its route, it is signed east–west. The South Carolina segment is signed such that US 52 north corresponds to the general westward direction of the highway, and vice versa.
U.S. Route 29 (US 29) is a 110.202-mile (177.353 km) north–south United States highway that travels from the Savannah River to Blacksburg, entirely in Upstate South Carolina.
South Carolina Highway 165 (SC 165) is a 28.393-mile (45.694 km) state highway in the U.S. state of South Carolina. It connects Yonges Island to U.S. Route 17 (US 17) in Ravenel and US 17 Alternate in Summerville.
South Carolina Highway 121 (SC 121) is a 134.200-mile (215.974 km) major state highway that travels north and south in central parts of the U.S. state of South Carolina. The highway is actually part of a long multi-state highway that also exists in Florida and Georgia, as Florida State Road 121 and Georgia State Route 121, respectively. Some see it as a de facto auxiliary route from U.S. Route 21 (US 21) in Rock Hill. Efforts to have the road upgraded to such status have failed however.
South Carolina Highway 125 (SC 125) is a 56.212-mile (90.464 km) primary state highway in the U.S. state of South Carolina. The highway serves as a direct route between Allendale and Augusta, Georgia, through the Savannah River Site (SRS); and an alternate to U.S. Route 278 (US 278).
South Carolina Highway 72 (SC 72) is a 124.860-mile (200.943 km) state highway, traversing interior portions of the South Carolina Piedmont region. This route is part of a multi two-state route 72 that begins at Athens, Georgia and ends at Rock Hill, South Carolina. The route connects many smaller communities outside major metropolitan areas and is roughly parallel with Interstate 85 (I-85) to the north and I-20 and I-77 to the south and east. The route shares the longest concurrency in the state with SC 121, from Whitmire to Rock Hill.
Several special routes of U.S. Route 25 exist. In order from south to north they are as follows.
South Carolina Highway 64 (SC 64) is a 73.730-mile (118.657 km) primary state highway in the U.S. state of South Carolina. It serves the cities of Barnwell and Walterboro while also providing a direct route to Charleston, via U.S. Route 17 (US 17).
South Carolina Highway 27 (SC 27) is a 19.511-mile (31.400 km) primary state highway in the U.S. state of South Carolina. It serves to connect the town of Ridgeville with nearby highways.
South Carolina Highway 45 (SC 45) is a 76.060-mile (122.407 km) primary state highway in the U.S. state of South Carolina. It serves as the main thoroughfare in northern Berkeley County.
South Carolina Highway 327 (SC 327) is a 22.623-mile (36.408 km) primary state highway in the U.S. state of South Carolina. It serves as an alternative bypass east of Florence and a connector route from Interstate 95 (I-95) to Myrtle Beach.
South Carolina Highway 20 (SC 20) is a primary state highway in the U.S. state of South Carolina. The highway connects the cities of Abbeville, Belton, Williamston and Greenville. The 53-mile-long (85 km) highway is signed as a west-east highway though it physically runs south-to-north.
South Carolina Highway 781 (SC 781) is a 3.561-mile (5.731 km) primary state highway in the U.S. state of South Carolina. It is used as part of a bypass south of Aiken, between Augusta and Williston, in conjunction with U.S. Route 278 (US 278).
South Carolina Highway 19 (SC 19) is a 28.750-mile (46.269 km) primary state highway in the U.S. state of South Carolina. It connects Aiken directly with the Savannah River Site and Edgefield via U.S. Route 25 (US 25).
South Carolina Highway 211 (SC 211) is a 27.380-mile (44.064 km) primary state highway in the U.S. state of South Carolina. The highway serves the rural areas of southern Cherokee and western York counties.
South Carolina Highway 18 (SC 18) is a 39.040-mile (62.829 km) primary state highway in the U.S. state of South Carolina. It serves to connect the cities of Union, Gaffney and Shelby, North Carolina.