Water fluoridation controversy

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The water fluoridation controversy arises from political, ethical, economic, and health considerations regarding the fluoridation of public water supplies. For deprived groups in both maturing and matured countries, international and national agencies and dental associations across the world support the safety and effectiveness of water fluoridation. [1] Proponents of water fluoridation see it as a question of public health policy and equate the issue to vaccination and food fortification, citing significant benefits to dental health and minimal risks. [2] [3] In contrast, opponents of water fluoridation view it as an infringement of individual rights, if not an outright violation of medical ethics, [4] on the basis that individuals have no choice in the water that they drink, unless they drink more expensive bottled water. [5] A small minority of scientists have challenged the medical consensus, variously claiming that water fluoridation has no or little cariostatic benefits, may cause serious health problems, is not effective enough to justify the costs, and is pharmacologically obsolete. [6] [7] [8] [9]

Contents

Opposition to fluoridation has existed since its initiation in the 1940s. [10] During the 1950s and 1960s, now-debunked conspiracy theorists claimed that fluoridation was a communist plot to undermine American public health. [11] In recent years, water fluoridation has become a prevalent health and political issue in many countries, resulting in some countries and communities discontinuing its use while others have expanded it. [12] [13] The controversy is propelled by a significant public opposition supported by a minority of professionals, [14] which include researchers, dental and medical professionals, alternative medical practitioners, health food enthusiasts, a few religious groups (mostly Christian Scientists in the U.S.), and occasionally consumer groups and environmentalists. [15] Organized political opposition has come from libertarians, [16] the John Birch Society, [17] the Ku Klux Klan, [18] and from groups like the Green parties in the UK and New Zealand. [19]

Proponents of fluoridation have been criticized for overstating the benefits, while opponents have been criticized for understating them and for overstating the risks. [20] [21] Systematic reviews have cited the lack of high quality research for the benefits and risks of water fluoridation and questions that are still unsettled. [12] [21] [22] [ needs update ] Researchers who oppose the practice state this as well. [23] According to a 2013 Congressional Research Service report on fluoride in drinking water, these gaps in the fluoridation scientific literature fuel the controversy. [13]

Public water fluoridation was first practiced in 1945, in the U.S. As of 2015, about 25 countries have supplemental water fluoridation to varying degrees, and 11 of them have more than 50% of their population drinking fluoridated water. A further 28 countries have water that is naturally fluoridated, though in many of them there are areas where fluoride is above the optimum level. [24] As of 2012, about 435 million people worldwide received water fluoridated at the recommended level, of whom 57 million (13%) received naturally fluoridated water and 377 million (87%) received artificially fluoridated water. [24] In 2014, three-quarters of the US population on the public water supply received fluoridated water, which represented two-thirds of the total US population. [25]

Medical consensus

National and international health agencies and dental associations throughout the world have endorsed water fluoridation as safe and effective. [1] [26] The views on the most effective method for community prevention of tooth decay are mixed. The Australian government states that water fluoridation is the most effective means of achieving fluoride exposure that is community-wide. [27] The World Health Organization states water fluoridation, when feasible and culturally acceptable, has substantial advantages, especially for subgroups at high risk, [28] while the European Commission finds no advantage to water fluoridation compared with topical use. [29]

FDI World Dental Federation supports water fluoridation as safe and effective. [24] the European Academy of Paediatric Dentistry, [30] and the national dental associations of Australia, [31] Canada, [32] and the U.S. [33] The American Dental Association calls water fluoridation "one of the safest and most beneficial, cost-effective public health measures for preventing, controlling, and in some cases reversing, tooth decay." [34]

In the English speaking nations—the United States, Canada, UK, Australia and New Zealand, all of which practice water fluoridation—many medical associations and authorities have published position statements and endorsed water fluoridation. The U.S. Surgeon General, [35] the American Public Health Association, [36] the Royal Commission on the National Health Service, [37] Australian Medical Association, [38] New Zealand Medical Association, [39] and Health Canada support fluoridation, citing a number of international scientific reviews that indicate "there is no link between any adverse health effects and exposure to fluoride in drinking water at levels that are below the maximum acceptable concentration of 1.5 mg/L." [40] The Centers for Disease Control and Prevention listed water fluoridation as one of the ten great public health achievements of the 20th century in the U.S., [41] along with vaccination, family planning, recognition of the dangers of smoking, and other achievements. [41]

In Israel, the Israeli Association of Public Health Physicians, the Israel Pediatric Association, and the Israel Dental Association, support fluoridation. [42] The World Health Organization, looking at global public health, identifies fluoride as one of a few chemicals for which the contribution from drinking-water to overall intake is an important factor in preventing disease. This is because there is clear evidence that optimal concentrations of fluoride provide protection against cavities, both in children and in adults. [43] [44] [45]

Minority scientific view

The scientists or doctors who oppose water fluoridation argue that it has no or little cariostatic benefits, may cause serious health problems, is not effective enough to justify the costs, and is pharmacologically obsolete. [7] [8] [9]

Evidence

Proponents and opponents have been both criticized for overstating the benefits or risks, and understating the other, respectively. [20] [21] Systematic reviews have cited the lack of high-quality research for the benefits and risks of water fluoridation and questions that are still unsettled. [12] [21] [22] A 2007 Nuffield Council on Bioethics report concluded that good evidence for or against water fluoridation is lacking. [46] Researchers who oppose the practice state this as well. [23] According to a 2013 Congressional Research Service report on fluoride in drinking water, these gaps in the fluoridation scientific literature fuel the controversy. [13] John Doull, chairman of the 2006 National Research Council committee report on fluoride in drinking water, has stated a similar conclusion regarding the source of the controversy: "In the scientific community, people tend to think this is settled. I mean, when the U.S. surgeon general comes out and says this is one of the 10 greatest achievements of the 20th century, that's a hard hurdle to get over. But when we looked at the studies that have been done, we found that many of these questions are unsettled and we have much less information than we should, considering how long this [fluoridation] has been going on. I think that's why fluoridation is still being challenged so many years after it began. In the face of ignorance, controversy is rampant." [47] [48]

Safety

Fluoride can be present naturally in water at concentrations well above recommended levels, which can have several long-term adverse effects, including severe dental fluorosis, skeletal fluorosis, and weakened bones. [49] In 1984 the World Health Organization recommended a guideline maximum fluoride value of 1.5 mg/L as a level at which fluorosis should be minimal, reaffirming it in 2006. [50]

Fluoridation has little effect on risk of bone fracture (broken bones); it may result in slightly lower fracture risk than either excessively high levels of fluoridation or no fluoridation. [27] There is no clear association between fluoridation and cancer or deaths due to cancer, both for cancer in general and also specifically for bone cancer and osteosarcoma. [27] [51]

In rare cases improper implementation of water fluoridation can result in overfluoridation that causes outbreaks of acute fluoride poisoning, with symptoms that include nausea, vomiting, and diarrhea. Three such outbreaks were reported in the U.S. between 1991 and 1998, caused by fluoride concentrations as high as 220 mg/L; in the 1992 Alaska outbreak, 262 people became ill and one person died. [52] In 2010, approximately 60 gallons of fluoride were released into the water supply in Asheboro, North Carolina, in 90 minutes—an amount that was intended to be released in a 24-hour period. [53]

Like other common water additives such as chlorine, hydrofluosilicic acid and sodium silicofluoride decrease pH and cause a small increase of corrosivity, but this problem is easily addressed by increasing the pH. [54] Although it has been hypothesized that hydrofluosilicic acid and sodium silicofluoride might increase human lead uptake from water, a 2006 statistical analysis did not support concerns that these chemicals cause higher blood lead concentrations in children. [55] Trace levels of arsenic and lead may be present in fluoride compounds added to water; however, concentrations are below measurement limits. [54]

The effect of water fluoridation on the natural environment has been investigated, and no adverse effects have been established. Issues studied have included fluoride concentrations in groundwater and downstream rivers; lawns, gardens, and plants; consumption of plants grown in fluoridated water; air emissions; and equipment noise. [54]

Efficacy

Reviews have shown that water fluoridation reduces cavities in children. [22] [29] [56] A conclusion for the efficacy in adults is less clear with some reviews finding benefit and others not. [22] [56] Studies in the U.S. in the 1950s and 1960s showed that water fluoridation reduced childhood cavities by fifty to sixty percent, while studies in 1989 and 1990 showed lower reductions (40% and 18% respectively), likely due to increasing use of fluoride from other sources, notably toothpaste, and also the "halo effect" of food and drink that is made in fluoridated areas and consumed in unfluoridated ones. [6]

A 2000 UK systematic review (York) found that water fluoridation was associated with a decreased proportion of children with cavities of 15% and with a decrease in decayed, missing, and filled primary teeth (average decreases was 2.25 teeth). The review found that the evidence was of moderate quality: few studies attempted to reduce observer bias, control for confounding factors, report variance measures, or use appropriate analysis. Although no major differences between natural and artificial fluoridation were apparent, the evidence was inadequate for a conclusion about any differences. [51] A 2002 systematic review found strong evidence that water fluoridation is effective at reducing overall tooth decay in communities. [57] A 2015 Cochrane review also found benefit in children. [22]

Fluoride may also prevent cavities in adults of all ages. A 2007 meta-analysis by CDC researchers found that water fluoridation prevented an estimated 27% of cavities in adults, about the same fraction as prevented by exposure to any delivery method of fluoride (29% average). [58] A 2011 European Commission review concluded that water fluoridation has no known advantage over topical prevention (e.g. through fluoride toothpaste). It also found that water fluoridation has limited benefit for adults, because the continued administration of systemic fluoride after the permanent teeth have erupted has questionable efficacy in preventing tooth decay. [29] A 2015 Cochrane review found no conclusive research in adults. [22]

Most countries in Europe have experienced substantial declines in cavities without the use of water fluoridation. [1] For example, in Finland and Germany, tooth decay rates remained stable or continued to decline after water fluoridation stopped. Fluoridation may be useful in the U.S. because unlike most European countries, the U.S. does not have school-based dental care, many children do not visit a dentist regularly, and for many U.S. children water fluoridation is the prime source of exposure to fluoride. [59] The effectiveness of water fluoridation can vary according to circumstances such as whether preventive dental care is free to all children. [60]

Ethics

Water fluoridation pits the common good against individual rights.[ citation needed ] Some say the common good overrides individual rights, and equate it to vaccination and food fortification. [2] [4] Others say that individual rights override the common good, and say that individuals have no choice in the water that they drink, unless they drink more expensive bottled water, [5] and some argue unequivocally that it does not stand up to scrutiny relative to the Nuremberg Code and other codes of medical ethics. [4]

Those who emphasize the public good emphasize the medical consensus that appropriate levels of water fluoridation are safe and effective to prevent cavities and see it as a public health intervention, replicating the benefits of naturally fluoridated water, which can free people from the misery and expense of tooth decay and toothache, with the greatest benefit accruing to those least able to help themselves. This perspective suggests it would be unethical to withhold such treatment. [61] In her book 50 Health Scares That Fizzled, Joan Callahan writes that, "For lower-income people with no insurance, fluoridated water (like enriched flour and fortified milk) looks more like a free preventative health measure that a few elitists are trying to take away." [62]

Those who emphasize individual or local choice, may view fluoridation as a violation of ethical or legal rules that prohibit medical treatment without medical supervision or informed consent or that prohibit administration of unlicensed medical substances, [1] [63] view it as "mass medication", [64] or may even characterize it as a violation of the Nuremberg Code and the Council of Europe's Biomedical Convention of 1999. [4] [13] [20] Another journal article suggested applying the precautionary principle to this controversy, which calls for public policy to reflect a conservative approach to minimize risk in the setting where harm is possible (but not necessarily confirmed) and where the science is not settled. [65] Others have opposed it on the grounds of potential financial conflicts of interest driven by the chemical industry. [66]

A 2007 Nuffield Council on Bioethics report reached a conclusion mainly on three points, stating that :

The report therefore concluded that local and regional democratic procedures are the most appropriate way to decide whether to fluoridate. [46] [67] [68] [69]

Opposition groups and campaigns

The controversy is propelled by a significant public opposition supported by a minority of professionals, [14] including researchers, dental and medical professionals, alternative medical practitioners such as chiropractors, health food enthusiasts, a few religious groups (mostly Christian Scientists in the U.S.), and occasionally consumer groups and environmentalists. [15] Organized political opposition has come from libertarians, [16] the John Birch Society, [17] the Ku Klux Klan, [18] and from groups like the Green parties in the UK and New Zealand. [19] [66] [17] : 219–254 

Opposition campaigns involve newspaper articles, talk radio, and public forums. Media reporters are often poorly equipped to explain the scientific issues, and are motivated to present controversy regardless of the underlying scientific merits. Websites, which are increasingly used by the public for health information, contain a wide range of material about fluoridation ranging from factual to fraudulent, with a disproportionate percentage opposed to fluoridation. Antifluoridationist literature links fluoride exposure to a wide variety of effects, including AIDS, allergy, Alzheimer's disease, arthritis, cancer, and low IQ, along with diseases of the gastrointestinal tract, kidney, pineal gland, and thyroid, though there is no scientific evidence linking fluoridation to these adverse health effects. [70] [71]

Public opinion

Many people do not know that fluoridation is meant to prevent tooth decay, or that natural or bottled water can contain fluoride. As fluoridation does not appear to be an important issue for the general public in the U.S., the debate may reflect an argument between two relatively small lobbies for and against fluoridation. [72] A survey of Australians in 2009 found that 70% supported and 15% opposed fluoridation. Those opposed were much more likely to score higher on outrage factors such as "unclear benefits". [73]

A study of focus groups from 16 European countries in 2003 found that fluoridation was opposed by a majority of focus group members in most of the countries, including France, Germany, and the UK. [72] A survey in Sheffield, UK, performed in 1999 found that while a 62% majority favored water fluoridation in the city, the 31% who were opposed expressed their preference with greater intensity than supporters. [74] Every year in the U.S., pro- and anti-fluoridationists face off in referendums or other public decision-making processes: in most of them, fluoridation is rejected. [15]

Use throughout the world

Percentage of population receiving fluoridated water, including both artificial and natural fluoridation, as of 2012: .mw-parser-output .div-col{margin-top:0.3em;column-width:30em}.mw-parser-output .div-col-small{font-size:90%}.mw-parser-output .div-col-rules{column-rule:1px solid #aaa}.mw-parser-output .div-col dl,.mw-parser-output .div-col ol,.mw-parser-output .div-col ul{margin-top:0}.mw-parser-output .div-col li,.mw-parser-output .div-col dd{page-break-inside:avoid;break-inside:avoid-column} .mw-parser-output .legend{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .legend-color{display:inline-block;min-width:1.25em;height:1.25em;line-height:1.25;margin:1px 0;text-align:center;border:1px solid black;background-color:transparent;color:black}.mw-parser-output .legend-text{} 80-100% 60-80% 40-60% 20-40% 1-20% < 1% unknown Water-fluoridation-extent-world-equirectangular.svg
Percentage of population receiving fluoridated water, including both artificial and natural fluoridation, as of 2012:
  80–100%
  60–80%
  40–60%
  20–40%
  1–20%
  < 1%
  unknown

A 2012 study found that 25 countries have artificial water fluoridation to varying degrees, with 11 of them delivering fluoridated water to more than 50% of their population. It found that a further 28 countries have water that is naturally fluoridated, though in many of them the fluoride concentration is above the maximum recommended level. About 435 million people worldwide received water fluoridated at the recommended level, [24] with about 211 million of them living in the United States. [76]

Despite support by public health organizations and dental authorities, the practice is controversial as a public health measure; some countries and communities have discontinued it, while others have expanded it. [12] [13] In the U.S., rejection in state and local communities is more likely when the decision is made by a public referendum; in Europe, most decisions against fluoridation have been made administratively. [10] Neither side of the dispute appears to be weakening or willing to concede. [15]

Water fluoridation is used in the United States, United Kingdom, Ireland, Canada, Australia, Israel, Hong Kong and a handful of other countries. Most countries failed to adopt fluoridation, yet experienced the same or greater decline in cavities as those countries that did fluoridate during the later half of the twentieth century. [77] The following nations previously fluoridated their water, but stopped the practice, with the years when water fluoridation started and stopped in parentheses:

In the United Kingdom a strategic health authority can direct a water company to fluoridate the water supply in an area if it is technically possible. The strategic health authority must consult with the local community and businesses in the affected area. The water company will act as a contractor in any new schemes and cannot refuse to fluoridate the supply. [82] In areas with complex water sources, water fluoridation is more difficult and more costly. Alternative fluoridation methods have been proposed, and implemented in some parts of the world. The World Health Organization (WHO) is currently assessing the effects of fluoridated toothpaste, milk fluoridation and salt fluoridation in Africa, Asia, and Europe. The WHO supports fluoridation of water in some areas. [83] In some other countries, sodium fluoride is added to table salt. [84]

History

Fluoridation began during a time of great optimism and faith in science and experts (the 1950s and 1960s); even then, the public frequently objected. Opponents drew on distrust of experts and unease about medicine and science. [85] Controversies include disputes over fluoridation's benefits and the strength of the evidence basis for these benefits, the difficulty of identifying harms, legal issues over whether water fluoride is a medicine, and the ethics of mass intervention. [20]

The first large fluoridation controversy occurred in Wisconsin in 1950. Fluoridation opponents questioned the ethics, safety, and efficacy of fluoridation. [86] New Zealand was the second country to fluoridate, and similar controversies arose there. [87] Fears about fluoride were likely exacerbated by the reputation of fluoride compounds as insect poisons and by early literature which tended to use terms such as "toxic" and "low grade chronic fluoride poisoning" to describe mottling from consumption of 6 mg/L of fluoride prior to tooth eruption, a level of consumption not expected to occur under controlled fluoridation. [88] When voted upon, the outcomes tend to be negative, and thus fluoridation has had a history of gaining through administrative orders in North America. [86]

Conspiracy theories involving fluoridation are common, and include claims that fluoridation was motivated by protecting the U.S. atomic bomb program from litigation, that (as famously parodied in the film Dr. Strangelove, where a deranged U.S. Air Force general claimed that it would "sap and impurify all of our precious bodily fluids") it is part of a Communist or New World Order plot to take over the world, that it was pioneered by a German chemical company to make people submissive to those in power, that behind the scenes it is promoted by the sugary food or phosphate fertilizer or aluminium industries, or that it is a smokescreen to cover failure to provide dental care to the poor. [70] One such theory is that fluoridation was a public-relations ruse sponsored by fluoride polluters such as the aluminium maker Alcoa and the Manhattan Project, with conspirators that included industrialist Andrew Mellon and the Mellon Institute's researcher Gerald J. Cox, the Kettering Laboratory of the University of Cincinnati, the Federal Security Agency's administrator Oscar R. Ewing, and public-relations strategist Edward Bernays. [89] Specific antifluoridation arguments change to match the spirit of the time. [90]

Illustration in a 1955 flier by the Keep America Committee, alleging that fluoridation was a Communist plot Unholy three cropped.png
Illustration in a 1955 flier by the Keep America Committee, alleging that fluoridation was a Communist plot

Outside North America, water fluoridation was adopted in some European countries, but in the late 1970s and early 1980s, Denmark and Sweden banned fluoridation when government panels found insufficient evidence of safety, and the Netherlands banned water fluoridation when "a group of medical practitioners presented evidence" that it caused negative effects in a percentage of the population.[ citation needed ]

Communist conspiracy theory (1940s–1960s)

Water fluoridation has frequently been the subject of conspiracy theories. During the "Second Red Scare" in the United States during the late 1940s and 1950s, and to a lesser extent in the 1960s, activists on the far right of American politics routinely asserted that fluoridation was part of a far-reaching plot to impose a socialist or communist regime. These opponents believed it was "another aspect of President Truman's drive to socialize medicine." [91] They also opposed other public health programs, notably mass vaccination and mental health services. [92] Their views were influenced by opposition to a number of major social and political changes that had happened in recent years: the growth of internationalism, particularly the UN and its programs; the introduction of social welfare provisions, particularly the various programs established by the New Deal; and government efforts to reduce perceived inequalities in the social structure of the United States. [93]

Others asserted the existence of "a Communist plot to deplete the brainpower and sap the strength of a generation of American children". [91] Dr. Charles Betts, a prominent anti-fluoridationist, charged that fluoridation was "better than using the atom bomb because the atom bomb has to be made, has to be transported to the place it is to be set off while poisonous fluorine has been placed right beside the water supplies by the Americans themselves ready to be dumped into the water mains whenever a Communist desires!" Similarly, a right-wing newsletter, the American Capsule News, claimed that "the Soviet General Staff is very happy about it. Anytime they get ready to strike, and their 5th column takes over, there are tons and tons of this poison 'standing by' municipal and military water systems ready to be poured in within 15 minutes." [11] This controversy had a direct impact on local program during the 1950s and 1960s, where referendums on introducing fluoridation were defeated in over a thousand Florida communities. It was not until as late as the 1990s that fluoridated water was consumed by the majority of the population of the United States. [92]

The communist conspiracy argument declined in influence by the mid-1960s, becoming associated in the public mind with irrational fear and paranoia. It was portrayed in Stanley Kubrick's 1964 film Dr. Strangelove , in which the character General Jack D. Ripper initiates a nuclear war in the hope of thwarting a communist plot to "sap and impurify" the "precious bodily fluids" of the American people with fluoridated water. Another satire appeared in the 1967 movie In Like Flint , in which a character's fear of fluoridation is used to indicate that he is insane. Some anti-fluoridationists claimed that the conspiracy theories were damaging their goals; Dr. Frederick Exner, an anti-fluoridation campaigner in the early 1960s, told a conference: "most people are not prepared to believe that fluoridation is a communist plot, and if you say it is, you are successfully ridiculed by the promoters. It is being done, effectively, every day ... some of the people on our side are the fluoridators' 'fifth column'." [11]

Later conspiracy theories

In 1987, Ian E. Stephens authored a self-published booklet, an extract of which was published in the Australian New Age publication Nexus in 1995. In it he claimed he was told by "Charles Elliot Perkins" that: "Repeated doses of infinitesimal amounts of fluoride will in time reduce an individual's power to resist domination by slowly poisoning and narcotising a certain area of the brain and will thus make him submissive to the will of those who wish to govern him ... Both the Germans and the Russians added sodium fluoride to the drinking water of prisoners of war to make them stupid and docile." These statements have been dismissed by reputable Holocaust historians as untrue, but they are regularly repeated to the present day in conspiracy publications and websites. [94]

2006 US NRC report

U.S. opponents of fluoridation were heartened by a 2006 National Research Council report about hazards of water naturally fluoridated to high levels; [48] the report recommended lowering the U.S. maximum limit of 4 mg/L for fluoride in drinking water. The EPA did not act on that recommendation. [95]

Court cases

Ireland

In Ryan v. Attorney General (1965), the Supreme Court of Ireland held that water fluoridation did not infringe the plaintiff's right to bodily integrity. [96] The court found that such a right to bodily integrity did exist, even though it was not explicitly mentioned in the Constitution of Ireland, thus establishing the doctrine of unenumerated rights in Irish constitutional law.

Netherlands

Water was fluoridated in large parts of the Netherlands from 1960 to 1973, at which point the Supreme Court of the Netherlands declared fluoridation of drinking water unauthorized. [97] The Dutch Court decided that authorities had no legal basis for adding chemicals to drinking water if they did not also improve safety. It was also stated as support that consumers cannot choose a different tap water provider. [98] Drinking water has not been fluoridated in any part of the Netherlands since 1973.

United States

Fluoridation has been the subject of many court cases wherein activists have sued municipalities, asserting that their rights to consent to medical treatment and due process are infringed by mandatory water fluoridation. [4] Individuals have sued municipalities for a number of illnesses that they believe were caused by fluoridation of the city's water supply. In most of these cases, the courts have held in favor of cities, finding no or only a tenuous connection between health problems and widespread water fluoridation. [99] To date, no federal appellate court or state court of last resort (i.e., state supreme court) has found water fluoridation to be unlawful. [100]

See also

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Henry Trendley Dean was the first director of the United States National Institute of Dental Research and a pioneer investigator of water fluoridation in the prevention of tooth decay.

<span class="mw-page-title-main">Dental public health</span> Prevention of oral disease and promotion of oral health

Dental Public Health (DPH) is a para-clinical specialty of dentistry that deals with the prevention of oral disease and promotion of oral health. Dental public health is involved in the assessment of key dental health needs and coming up with effective solutions to improve the dental health of populations rather than individuals.

<span class="mw-page-title-main">Oral hygiene</span> Cleaning the mouth by brushing the teeth and cleaning in between the teeth

Oral hygiene is the practice of keeping one's oral cavity clean and free of disease and other problems by regular brushing of the teeth and adopting good hygiene habits. It is important that oral hygiene be carried out on a regular basis to enable prevention of dental disease and bad breath. The most common types of dental disease are tooth decay and gum diseases, including gingivitis, and periodontitis.

<span class="mw-page-title-main">Fluoride varnish</span> Highly concentrated form of fluoride

Fluoride varnish is a highly concentrated form of fluoride that is applied to the tooth's surface by a dentist, dental hygienist or other dental professional, as a type of topical fluoride therapy. It is not a permanent varnish but due to its adherent nature it is able to stay in contact with the tooth surface for several hours. It may be applied to the enamel, dentine or cementum of the tooth and can be used to help prevent decay, remineralise the tooth surface and to treat dentine hypersensitivity. There are more than 30 fluoride-containing varnish products on the market today, and they have varying compositions and delivery systems. These compositional differences lead to widely variable pharmacokinetics, the effects of which remain largely untested clinically.

<span class="mw-page-title-main">Water fluoridation by country</span>

Water fluoridation is the controlled addition of fluoride to a public water supply to reduce tooth decay, and is handled differently by countries across the world. Fluoridated water contains fluoride at a level that is proven effective for preventing cavities; this can occur naturally or by adding fluoride. Fluoridated water creates low levels of fluoride in saliva, which reduces the rate at which tooth enamel demineralizes, and increases the rate at which it remineralizes in the early stages of cavities. Typically, a fluoridated compound is added to drinking water, a process that in the U.S. costs an average of about $1.32 per person-year. Defluoridation is needed when the naturally occurring fluoride level exceeds recommended limits. In 2011, the World Health Organization suggested a level of fluoride from 0.5 to 1.5 mg/L, depending on climate, local environment, and other sources of fluoride. Bottled water typically has unknown fluoride levels.

<span class="mw-page-title-main">Remineralisation of teeth</span>

Tooth remineralization is the natural repair process for non-cavitated tooth lesions, in which calcium, phosphate and sometimes fluoride ions are deposited into crystal voids in demineralised enamel. Remineralization can contribute towards restoring strength and function within tooth structure.

<span class="mw-page-title-main">Water fluoridation in the United States</span>

Water fluoridation in the United States is common amongst most states. As of May 2000, 42 of the 50 largest U.S. cities had water fluoridation. On January 25, 1945, Grand Rapids, Michigan, became the first community in the United States to fluoridate its drinking water for the intended purpose of helping to prevent tooth decay.

Dentistry for babies is a branch of pediatric dentistry provided to children from birth to around 36 months of age, aiming to maintain or re-establish a good oral health status and create a positive attitude in parents and children about dentistry. Although concerns about dental treatment directed to babies have been reported at the beginning of the twentieth century, only recently has the dental community started to focus on this area of dentistry, due to the high dental caries (decay) prevalence observed in young children.

Silver diammine fluoride (SDF), also known as silver diamine fluoride in most of the dental literature, is a topical medication used to treat and prevent dental caries and relieve dentinal hypersensitivity. It is a colorless or blue-tinted, odourless liquid composed of silver, ammonium and fluoride ions at a pH of 10.4 or 13. Ammonia compounds reduce the oxidative potential of SDF, increase its stability and helps to maintain a constant concentration over a period of time, rendering it safe for use in the mouth. Silver and fluoride ions possess antimicrobial properties and are used in the remineralization of enamel and dentin on teeth for preventing and arresting dental caries.

Topical fluorides are fluoride-containing drugs indicated in prevention and treatment of dental caries, particularly in children's primary dentitions. The dental-protecting property of topical fluoride can be attributed to multiple mechanisms of action, including the promotion of remineralization of decalcified enamel, the inhibition of the cariogenic microbial metabolism in dental plaque and the increase of tooth resistance to acid dissolution. Topical fluoride is available in a variety of dose forms, for example, toothpaste, mouth rinses, varnish and silver diamine solution. These dosage forms possess different absorption mechanisms and consist of different active ingredients. Common active ingredients include sodium fluoride, stannous fluoride, silver diamine fluoride. These ingredients account for different pharmacokinetic profiles, thereby having varied dosing regimes and therapeutic effects. A minority of individuals may experience certain adverse effects, including dermatological irritation, hypersensitivity reactions, neurotoxicity and dental fluorosis. In severe cases, fluoride overdose may lead to acute toxicity. While topical fluoride is effective in preventing dental caries, it should be used with caution in specific situations to avoid undesired side effects.

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