William Gaines (1922–1992) was an American publisher, notably of Mad magazine.
William Maxwell Gaines, was an American publisher and co-editor of EC Comics. Following a shift in EC's direction in 1950, Gaines presided over what became an artistically influential and historically important line of mature-audience comics. He published the satirical magazine Mad for over 40 years.
William Gaines may also refer to:
- William E. Gaines (1844–1912), U.S. Representative from Virginia
- William Gaines (professor) (1933–2016), American journalist and professor
- William Gaines (American football) (born 1971), American footballer
- Bill Gaines (basketball) (born 1946), retired basketball guard
- William Gaines (minister and community leader), a freed slave who was a minister and community representative during the Reconstruction Era in Georgia
William Embre Gaines was a U.S. Representative from Virginia.
William C. Gaines was an American journalist and professor of journalism. Gaines was a Pulitzer Prize-winning investigative reporter for the Chicago Tribune. He retired from the paper in 2001 and taught in the Department of Journalism at the University of Illinois at Urbana-Champaign until his retirement and designation as an emeritus faculty member in 2007. He died July 20, 2016 at the age of 82.
William Albert Gaines is an American former college and professional football player who was a defensive lineman in the National Football League (NFL) for four seasons during the 1990s. Gaines played college football for the University of Florida, and thereafter, he played professionally for the Washington Redskins and Chicago bears of the NFL.
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