![]() | |
Combination of | |
---|---|
Adapalene | Retinoid |
Benzoyl peroxide | Peroxide |
Clinical data | |
Trade names | Epiduo, Epiduo Forte, Tactupump Forte, Desarena, Effezel, Belakne Combi, Aciduo |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
License data | |
Routes of administration | Topical |
ATC code | |
Legal status | |
Legal status | |
Identifiers | |
CAS Number | |
KEGG | |
![]() ![]() |
Adapalene/benzoyl peroxide, sold under the brand name Epiduo among others, is a fixed-dose combination medication for the treatment of acne vulgaris. [2] [3] It is a combination of adapalene, a retinoid; and benzoyl peroxide. [2] [3]
It is available as a generic medication. [4] In 2023, it was the 319th most commonly prescribed medication in the United States, with more than 200,000 prescriptions. [5]
Adapalene/benzoyl peroxide is indicated for the topical treatment of acne vulgaris. [2] [3]
Commonly reported side effects include the following: [2] [3]
Meta-analysis of clinical trials has shown this combined therapy to be more effective than either of its ingredients by themselves. [6]
The use of adapalene/benzoyl peroxide in combination with oral antibiotics (lymecycline) has been studied; [7] the combination was well tolerated and showed an improved success rate compared to those receiving only antibiotics (47.6% vs. 33.7%, P = 0.002).