Amlodipine/olmesartan

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Amlodipine/olmesartan
Combination of
Amlodipine Calcium channel blocker
Olmesartan Angiotensin II antagonist
Clinical data
Trade names Azor, Sevikar
Other namesOlmesartan/amlodipine
AHFS/Drugs.com Micromedex Detailed Consumer Information
License data
Pregnancy
category
Routes of
administration 		By mouth
ATC code
Legal status
Legal status
Identifiers
CAS Number
KEGG

Amlodipine/olmesartan, sold under the brand name Azor, among others is a fixed-dose combination medication used to treat high blood pressure. [5] It contains amlodipine, as the besilate, a dihydropyridine calcium channel blocker, and olmesartan medoxomil, an angiotensin II receptor blocker. [5]

Contents

Amlodipine/olmesartan was approved for medical use in the United States in September 2007. [5] [7] It is available as a generic medication.

Medical uses

The combination is indicated for the treatment of hypertension, alone or with other antihypertensive agents, to lower blood pressure. [5]

History

The combination has been studied in clinical trials; one test showed it reduced blood pressure during a 24-hour period and was well tolerated. [8]

References

  1. ↑ "TGA eBS - Product and Consumer Medicine Information Licence". www.ebs.tga.gov.au.
  2. ↑ "OLAMLO, OLMAKAR, OLMESARTAN/AMLODIPINE ASTRON, OLMESARTAN/AMLODIPINE INTAS (Accord Healthcare Pty Ltd)". Department of Health and Aged Age. Retrieved 3 April 2023.
  3. ↑ "SEVIKAR 20/5 olmesartan medoxomil / amlodipine (as besilate) 20/5 mg tablet blister pack (157565)". Therapeutic Goods Administration (TGA). 27 May 2022. Retrieved 3 April 2023.
  4. ↑ "Sevikar 20 mg/5 mg Film-Coated Tablets - Summary of Product Characteristics (SmPC)". (emc). 11 July 2022. Retrieved 19 March 2023.
  5. 1 2 3 4 5 "Azor- amlodipine besylate and olmesartan medoxomil tablet, film coated". DailyMed. 7 September 2022. Retrieved 17 March 2023.
  6. ↑ "Azor- amlodipine besylate and olmesartan medoxomil tablet, film coated". DailyMed. 7 June 2022. Retrieved 18 March 2023.
  7. ↑ "Drug Approval Package: Azor (amlodipine and olmesartan medoxomil) NDA #022100". U.S. Food and Drug Administration (FDA). 17 December 2009. Retrieved 17 March 2023.[ dead link ]
  8. ↑ Alexander W (June 2009). "American society of hypertension and american urological association". P & T. 34 (6). Pharmacy & Therapeutics: 318–21. PMC   2697919 . PMID   19572050.
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