Medalists
| Gold | Silver | Bronze |
|---|---|---|
| Carlos Quishpe Bayron de la Cruz  Ecuador | Sebastian Donadio Walter Pérez  Argentina | Carlos Ospina Weimar Roldán  Colombia |
The Men's Madison event at the 2010 South American Games was held on March 21.
| Gold | Silver | Bronze |
|---|---|---|
| Carlos Quishpe Bayron de la Cruz Ecuador | Sebastian Donadio Walter Pérez Argentina | Carlos Ospina Weimar Roldán Colombia |
Distance: 140 laps (35 km) with 7 sprint
Elapsed time: 43:20.170
Average Speed: 48.458 km/h
| Rank | Rider | Sprint | Finish | Total | Laps Down | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | |||||
 | Ecuador Carlos Quishpe Bayron de la Cruz | 5 | 0 | ||||||||
 | Argentina Sebastian Donadio Walter Pérez | 5 | 3 | 2 | 5 | 5 | 1 | 20 | –1 | ||
 | Colombia Carlos Ospina Weimar Roldán | 3 | 3 | 5 | 1 | 2 | 2 | 3 | 2 | 19 | –1 |
| 4 |  Venezuela Maximo Rojas Yosvangs Rojas | 2 | 2 | 1 | 3 | 5 | 3 | 2 | 3 | 18 | –1 |
| 5 |  Chile Luis Sepulveda Villar Gonzalo Figueroa | 5 | 1 | 2 | 3 | 1 | 1 | 4 | 13 | –1 | |
| 6 |  Uruguay Edgard Nicolas Palma Milton Wynants | 5 | 5 | –1 | |||||||
| 7 |  Brazil Thiago Nardin Marcos Novello | 1 | 1 | 2 | –1 | ||||||