David Grimes may refer to:
- David Grimes (American football) (born 1986), American football wide receiver
- David Grimes (composer) (born 1948), American composer
- David Grimes (physician) (born 1947), American physician and abortion provider
- David Robert Grimes (born 1985), physicist and cancer researcher at the University of Oxford
- David Grimes (meteorologist), Canadian meteorologist
- David Grimes (politician), Alabama state legislator
This disambiguation page lists articles about people with the same name.
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