Endonuclease/exonuclease/phosphatase family domain containing 1

EEPD1
Identifiers
Aliases	EEPD1 , HSPC107, endonuclease/exonuclease/phosphatase family domain containing 1
External IDs	OMIM: 617192 MGI: 1914734 HomoloGene: 12144 GeneCards: EEPD1
Gene location (Human)
Chr.	Chromosome 7 (human)
End	36,301,538 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	25,515,406 bp
RNA expression pattern
	Top expressed in
	muscle tissue; ; gastrocnemius muscle; ; body of stomach; ; subcutaneous adipose tissue; ; muscle of leg;
	More reference expression data
	n/a
Orthologs
	80820
	67484
	ENSG00000122547
	ENSMUSG00000036611
	Q7L9B9
	Q3TGW2
	NM_030636
	NM_026189
	NP_085139
	NP_080465
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated April 14, 2022

Endonuclease/exonuclease/phosphatase family domain containing 1 is a protein that in humans is encoded by the EEPD1 gene. ^[5]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000122547 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000036611 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Endonuclease/exonuclease/phosphatase family domain containing 1" . Retrieved 2018-05-21.

Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464 . PMID 20379614.
Wu Y, Lee SH, Williamson EA, Reinert BL, Cho JH, Xia F, Jaiswal AS, Srinivasan G, Patel B, Brantley A, Zhou D, Shao L, Pathak R, Hauer-Jensen M, Singh S, Kong K, Wu X, Kim HS, Beissbarth T, Gaedcke J, Burma S, Nickoloff JA, Hromas RA (December 2015). "EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair". PLOS Genet. 11 (12): e1005675. doi:10.1371/journal.pgen.1005675. PMC 4684289 . PMID 26684013.
Kim HS, Nickoloff JA, Wu Y, Williamson EA, Sidhu GS, Reinert BL, Jaiswal AS, Srinivasan G, Patel B, Kong K, Burma S, Lee SH, Hromas RA (February 2017). "Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks". J. Biol. Chem. 292 (7): 2795–2804. doi: 10.1074/jbc.M116.758235 . PMC 5314175 . PMID 28049724.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000122547 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000036611 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Endonuclease/exonuclease/phosphatase family domain containing 1" . Retrieved 2018-05-21.

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Endonuclease/exonuclease/phosphatase family domain containing 1

Related Research Articles

References

Further reading