Esca can refer to:
- Esca (fish anatomy) or illicium, a modified luminescent fin ray found in anglerfish and frogfish
- Esca (grape disease)
- the Ezka, a river in the Basque country known as "Esca" in Spanish
- ESCA or Electron Spectroscopy for Chemical Analysis, now known as X-ray photoelectron spectroscopy (XPS)
This disambiguation page lists articles associated with the title Esca.
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