Estradiol/norethisterone acetate

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Estradiol/norethisterone acetate
Combination of
Estradiol Estrogen
Norethisterone acetate Progestogen
Clinical data
Trade names Activella, Amabelz, CombiPatch, others
AHFS/Drugs.com Professional Drug Facts
MedlinePlus a601041
Routes of
administration 		By mouth
ATC code
Legal status
Legal status
Identifiers
CAS Number
ChemSpider
  • none
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Estradiol/norethisterone acetate (E2/NETA), sold under the brand name Activella among others, is a combination of estradiol (E2) and norethisterone acetate (NETA) which is used in the treatment of vasomotor symptoms, vulvar and vaginal atrophy, and osteoporosis [1] associated with menopause. [2] Activella specifically is marketed by Novo Nordisk and is supplied as film-coated tablets containing 1 mg estradiol and 0.5 mg norethisterone acetate. CombiPatch is a combination of estradiol and NETA provided as a transdermal patch. [2]

See also

References

  1. ↑ Morabito N, Crisafulli A, Vergara C, Gaudio A, Lasco A, Frisina N, et al. (October 2002). "Effects of genistein and hormone-replacement therapy on bone loss in early postmenopausal women: a randomized double-blind placebo-controlled study". Journal of Bone and Mineral Research. 17 (10): 1904–12. doi: 10.1359/jbmr.2002.17.10.1904 . PMID   12369794. S2CID   29312298.
  2. 1 2 "CombiPatch (estradiol/norethindrone acetate transdermal system) Prescribing Information" (PDF). Noven Pharmaceuticals, Inc. U.S. Food and Drug Administration. Archived from the original (PDF) on January 27, 2020.
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