The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. It is a 13kb gene on chromosome 21q22.3 that has 545 amino acids. AIRE is a transcription factor expressed in the medulla of the thymus. It is part of the mechanism which eliminates self-reactive T cells that would cause autoimmune disease. It exposes T cells to normal, healthy proteins from all parts of the body, and T cells that react to those proteins are destroyed.
Folate transporter 1 is a protein which in humans is encoded by the SLC19A1 gene.
C-C chemokine receptor-like 2 is a protein that in humans is encoded by the CCRL2 gene. Recently it was found that CCRL2 also acts as a receptor for the chemokine chemerin.
Dual specificity tyrosine-phosphorylation-regulated kinase 1A is an enzyme that in humans is encoded by the DYRK1A gene. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode for at least five different isoforms.
ATP-binding cassette sub-family G member 1 is a protein that in humans is encoded by the ABCG1 gene. It is a homolog of the well-known Drosophila gene white.
Glucosamine—fructose-6-phosphate aminotransferase isomerizing 1 is an enzyme that in humans is encoded by the GFPT1 gene.
Calumenin is a protein that in humans is encoded by the CALU gene.
28S ribosomal protein S12, mitochondrial is a protein that in humans is encoded by the MRPS12 gene.
Trafficking protein particle complex subunit 10 is a protein that in humans is encoded by the TRAPPC10 gene.
Ribosomal RNA processing protein 1 homolog A is a protein that in humans is encoded by the RRP1 gene.
T-complex protein 10A homolog 2 is a protein that in humans is encoded by the TCP10L gene. It is located next to CFAP298.
ATP synthase subunit O, mitochondrial is an enzyme that in humans is encoded by the ATP5PO gene.
39S ribosomal protein L20, mitochondrial is a protein that in humans is encoded by the MRPL20 gene.
Periodic tryptophan protein 2 homolog is a protein that in humans is encoded by the PWP2 gene.
tRNA -methyltransferase subunit WDR4 is an enzyme subunit that in humans is encoded by the WDR4 gene.
Forkhead box protein D4 is a protein that in humans is encoded by the FOXD4 gene.
Protein Mis18-alpha is a protein that in humans is encoded by the MIS18A gene.
Chloride intracellular channel protein 6 is a protein that in humans is encoded by the CLIC6 gene.
RWD domain-containing protein 2B is a protein that in humans is encoded by the RWDD2B gene.
Subunit P of phosphatidylinositol N-acetylglucosaminyltransferase is an enzyme subunit that in humans is encoded by the PIGP gene.
