The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. It is a 13kbp gene on chromosome 21q22.3 that encodes 545 amino acids. AIRE is a transcription factor expressed in the medulla of the thymus. It is part of the mechanism which eliminates self-reactive T cells that would cause autoimmune disease. It exposes T cells to normal, healthy proteins from all parts of the body, and T cells that react to those proteins are destroyed.
Dual specificity tyrosine-phosphorylation-regulated kinase 1A is an enzyme that in humans is encoded by the DYRK1A gene. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode for at least five different isoforms.
ATP-binding cassette sub-family G member 1 is a protein that in humans is encoded by the ABCG1 gene. It is a homolog of the well-known Drosophila gene white.
Chromatin assembly factor 1 subunit B is a protein that in humans is encoded by the CHAF1B gene.
Interleukin-1 family member 10 is a protein that in humans is encoded by the IL1F10 gene.
60S ribosomal protein L36a is a protein that in humans is encoded by the RPL36A gene.
39S ribosomal protein L28, mitochondrial is a protein that in humans is encoded by the MRPL28 gene.
Solute carrier family 35 member C2 is a protein that in humans is encoded by the SLC35C2 gene.
Trafficking protein particle complex subunit 10 is a protein that in humans is encoded by the TRAPPC10 gene.
Ribosomal RNA processing protein 1 homolog A is a protein that in humans is encoded by the RRP1 gene.
39S ribosomal protein L11, mitochondrial is a protein that in humans is encoded by the MRPL11 gene.
T-complex protein 10A homolog 2 is a protein that in humans is encoded by the TCP10L gene. It is located next to CFAP298.
39S ribosomal protein L22, mitochondrial is a protein that in humans is encoded by the MRPL22 gene.
ATP synthase subunit O, mitochondrial is an enzyme that in humans is encoded by the ATP5PO gene.
39S ribosomal protein L20, mitochondrial is a protein that in humans is encoded by the MRPL20 gene.
Periodic tryptophan protein 2 homolog is a protein that in humans is encoded by the PWP2 gene.
tRNA -methyltransferase subunit WDR4 is an enzyme subunit that in humans is encoded by the WDR4 gene.
Protein Mis18-alpha is a protein that in humans is encoded by the MIS18A gene.
Quinone oxidoreductase-like protein 1 is an enzyme that in humans is encoded by the CRYZL1 gene.
Subunit P of phosphatidylinositol N-acetylglucosaminyltransferase is an enzyme subunit that in humans is encoded by the PIGP gene.
