GATD3

GATD3
Identifiers
Aliases	GATD3 , ES1, GT335, HES1, KNPH, KNPI, chromosome 21 open reading frame 33, C21orf33, glutamine amidotransferase like class 1 domain containing 3A, glutamine amidotransferase class 1 domain containing 3A, GATD3A, glutamine amidotransferase class 1 domain containing 3
External IDs	OMIM: 601659; MGI: 1351861; HomoloGene: 3416; GeneCards: GATD3; OMA:GATD3 - orthologs
Gene location (Human) Chr. Chromosome 21 (human) [1] Band 21q22.3 Start 44,133,610 bp [1] End 44,210,114 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10 C1|10 39.72 cM Start 77,997,900 bp [2] End 78,005,616 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon gastric mucosa stromal cell of endometrium gastrocnemius muscle left ventricle canal of the cervix fundus right hemisphere of cerebellum right ovary prefrontal cortex Top expressed in right ventricle myocardium of ventricle digastric muscle brown adipose tissue sternocleidomastoid muscle temporal muscle cardiac muscles muscle of thigh triceps brachii muscle interventricular septum More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 8209 28295 Ensembl ENSG00000160221 ENSMUSG00000053329 UniProt F2Z2Q0 H7C1F6 Q9D172 RefSeq (mRNA) NM_004649 NM_198155 NM_001320383 NM_001320384 NM_138601 NM_001364646 RefSeq (protein) NP_001307312 NP_001307313 NP_004640 NP_937798 NP_001350687 NP_001350689 NP_001350690 NP_613067 NP_001351575 Location (UCSC) Chr 21: 44.13 – 44.21 Mb Chr 10: 78 – 78.01 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial is a protein that in humans is encoded by the GATD3 gene. ^{[5] [6] [7]}

See also

• Glutamine amidotransferase

References

1. GRCh38: Ensembl release 89: ENSG00000160221 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000053329 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Scott HS, Chen H, Rossier C, Lalioti MD, Antonarakis SE (Jun 1997). "Isolation of a human gene (HES1) with homology to an Escherichia coli and a zebrafish protein that maps to chromosome 21q22.3". Hum Genet. 99 (5): 616–23. doi:10.1007/s004390050416. PMID   9150728. S2CID   22793851.
6. Lafreniere RG, Rochefort DL, Kibar Z, Fon EA, Han F, Cochius J, Kang X, Baird S, Korneluk RG, Andermann E, Rommens JM, Rouleau GA (Mar 1997). "Isolation and characterization of GT335, a novel human gene conserved in Escherichia coli and mapping to 21q22.3". Genomics. 38 (3): 264–72. doi:10.1006/geno.1996.0627. PMID   8975701.
7. "GATD3A glutamine amidotransferase like class 1 domain containing 3A [ Homo sapiens (human) ]".

External links

• Human C21orf33 genome location and C21orf33 gene details page in the UCSC Genome Browser .
• Human HES1 genome location and HES1 gene details page in the UCSC Genome Browser .

Further reading

• Hochstrasser DF, Frutiger S, Paquet N, et al. (1993). "Human liver protein map: a reference database established by microsequencing and gel comparison". Electrophoresis. 13 (12): 992–1001. doi:10.1002/elps.11501301201. PMID   1286669. S2CID   23518983.
• Nagamine K, Kudoh J, Minoshima S, et al. (1996). "Isolation of cDNA for a novel human protein KNP-I that is homologous to the E. coli SCRP-27A protein from the autoimmune polyglandular disease type I (APECED) region of chromosome 21q22.3". Biochem. Biophys. Res. Commun. 225 (2): 608–16. doi:10.1006/bbrc.1996.1218. PMID   8753807.
• Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. doi: 10.1101/gr.6.9.807 . PMID   8889549.
• Kudoh J, Nagamine K, Asakawa S, et al. (1997). "Localization of 16 exons to a 450-kb region involved in the autoimmune polyglandular disease type I (APECED) on human chromosome 21q22.3". DNA Res. 4 (1): 45–52. doi: 10.1093/dnares/4.1.45 . PMID   9179495.
• Nagamine K, Kudoh J, Minoshima S, et al. (1997). "Genomic organization and complete nucleotide sequence of the human PWP2 gene on chromosome 21". Genomics. 42 (3): 528–31. doi:10.1006/geno.1997.4761. PMID   9205129.
• Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21". Nature. 405 (6784): 311–9. Bibcode:2000Natur.405..311H. doi: 10.1038/35012518 . PMID   10830953.
• Yan B, Raben N, Plotz P (2002). "The human acid alpha-glucosidase gene is a novel target of the Notch-1/Hes-1 signaling pathway". J. Biol. Chem. 277 (33): 29760–4. doi: 10.1074/jbc.M204721200 . PMID   12065598.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Shin JH, Weitzdoerfer R, Fountoulakis M, Lubec G (2004). "Expression of cystathionine beta-synthase, pyridoxal kinase, and ES1 protein homolog (mitochondrial precursor) in fetal Down syndrome brain". Neurochem. Int. 45 (1): 73–9. doi:10.1016/j.neuint.2003.12.004. PMID   15082224. S2CID   20620865.
• Hartman J, Müller P, Foster JS, et al. (2005). "HES-1 inhibits 17beta-estradiol and heregulin-beta1-mediated upregulation of E2F-1". Oncogene. 23 (54): 8826–33. doi:10.1038/sj.onc.1208139. PMID   15467735. S2CID   21768068.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.