The beagle is a breed of small hound that is similar in appearance to the much larger foxhound. The beagle is a scent hound, developed primarily for hunting hare (beagling). With a great sense of smell and superior tracking instinct, the beagle is employed as detection dog for prohibited agricultural imports and foodstuffs in quarantine around the world. The beagle is intelligent but single-minded. It is a popular pet due to its size, good temper, and lack of inherited health problems.
Tierra del Fuego is an archipelago off the southernmost tip of the South American mainland, across the Strait of Magellan. The archipelago consists of the main island, Isla Grande de Tierra del Fuego, with an area of 48,100 km2 (18,572 sq mi), and a group of many islands, including Cape Horn and Diego Ramírez Islands. Tierra del Fuego is divided between Chile and Argentina, with the latter controlling the eastern half of the main island and the former the western half plus the islands south of Beagle Channel. The southernmost extent of the archipelago is at about latitude 55 S.
Rheumatology is a branch of medicine devoted to the diagnosis and therapy of rheumatic diseases. Physicians who have undergone formal training in rheumatology are called rheumatologists. Rheumatologists deal mainly with immune-mediated disorders of the musculoskeletal system, soft tissues, autoimmune diseases, vasculitides, and heritable connective tissue disorders.
The Beagle 2 was a British Mars lander that was transported by the European Space Agency's 2003 Mars Express mission. It was an astrobiology mission that would have looked for past life on the shallow surface of Mars.
Arthralgia literally means joint pain. Specifically, arthralgia is a symptom of injury, infection, illness, or an allergic reaction to medication.
Immunodeficiency is a state in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. Most cases of immunodeficiency are acquired ("secondary") due to extrinsic factors that affect the patient's immune system. Examples of these extrinsic factors include HIV infection, extremes of age, and environmental factors, such as nutrition. In the clinical setting, the immunosuppression by some drugs, such as steroids, can be either an adverse effect or the intended purpose of the treatment. Examples of such use is in organ transplant surgery as an anti-rejection measure and in patients suffering from an overactive immune system, as in autoimmune diseases. Some people are born with intrinsic defects in their immune system, or primary immunodeficiency. A person who has an immunodeficiency of any kind is said to be immunocompromised. An immunocompromised person may be particularly vulnerable to opportunistic infections, in addition to normal infections that could affect everyone. Immunodeficiency also decreases cancer immunosurveillance, in which the immune system scans the body's cells and kills neoplastic ones.
Peter Soyer Beagle is an American novelist and screenwriter, especially fantasy fiction. His best-known work is The Last Unicorn (1968), a fantasy novel he wrote in his twenties, which Locus subscribers voted the number five "All-Time Best Fantasy Novel" in 1987. During the last twenty-five years he has won several literary awards, including a World Fantasy Award for Life Achievement in 2011. He was named Damon Knight Memorial Grand Master by SFWA in 2018.
Bursitis is the inflammation of one or more bursae of synovial fluid in the body. They are lined with a synovial membrane that secretes a lubricating synovial fluid. There are more than 150 bursae in the human body. The bursae rest at the points where internal functionaries, such as muscles and tendons, slide across bone. Healthy bursae create a smooth, almost frictionless functional gliding surface making normal movement painless. When bursitis occurs, however, movement relying on the inflamed bursa becomes difficult and painful. Moreover, movement of tendons and muscles over the inflamed bursa aggravates its inflammation, perpetuating the problem. Muscle can also be stiffened.
Lymphocytopenia is the condition of having an abnormally low level of lymphocytes in the blood. Lymphocytes are a white blood cell with important functions in the immune system. The opposite is lymphocytosis, which refers to an excessive level of lymphocytes.
Neuroimmunology is a field combining neuroscience, the study of the nervous system, and immunology, the study of the immune system. Neuroimmunologists seek to better understand the interactions of these two complex systems during development, homeostasis, and response to injuries. A long-term goal of this rapidly developing research area is to further develop our understanding of the pathology of certain neurological diseases, some of which have no clear etiology. In doing so, neuroimmunology contributes to development of new pharmacological treatments for several neurological conditions. Many types of interactions involve both the nervous and immune systems including the physiological functioning of the two systems in health and disease, malfunction of either and or both systems that leads to disorders, and the physical, chemical, and environmental stressors that affect the two systems on a daily basis.
Felty's syndrome, also called Felty syndrome, (FS) is rare autoimmune disease characterized by the triad of rheumatoid arthritis, enlargement of the spleen and too few neutrophils in the blood. The condition is more common in those aged 50–70 years, specifically more prevalent in females than males, and more so in Caucasians than those of African descent. It is a deforming disease that causes many complications for the individual.
Beagle is a crater lying within the Margaritifer Sinus quadrangle (MC-19) portion of the planet Mars, the crater is one of multiple topographical depressions within the Meridiani Planum extraterrestrial plain, which was explored by the Opportunity rover. It was located by the rover in images taken on sol 855, 310 metres (1,107 ft) away. It is on the edge of the much larger ejecta blanket surrounding the crater Victoria, named the Victoria Annulus. This impact crater was named in honor of HMS Beagle of the Royal Navy, ordered in February 1817.
The Beagle-Harrier is a scenthound. It is a breed of dog originating from France.
Osteoimmunology is a field that emerged about 40 years ago that studies the interface between the skeletal system and the immune system, comprising the “osteo-immune system”. Osteoimmunology also studies the shared components and mechanisms between the two systems in vertebrates, including ligands, receptors, signaling molecules and transcription factors. Over the past decade, osteoimmunology has been investigated clinically for the treatment of bone metastases, rheumatoid arthritis (RA), osteoporosis, osteopetrosis, and periodontitis. Studies in osteoimmunology reveal relationships between molecular communication among blood cells and structural pathologies in the body.
An immune disorder is a dysfunction of the immune system. These disorders can be characterized in several different ways:
The Consort beagles campaign was founded in 1996 by British animal rights activists Greg Avery and Heather James, with a view to closing Consort Kennels in Hereford, a commercial breeder of beagles for animal testing laboratories.
Type III hypersensitivity occurs when there is accumulation of immune complexes that have not been adequately cleared by innate immune cells, giving rise to an inflammatory response and attraction of leukocytes. Such reactions may progress to immune complex diseases.
An autoimmune disease is a condition arising from an abnormal immune response to a normal body part. There are at least 80 types of autoimmune diseases. Nearly any body part can be involved. Common symptoms include low grade fever and feeling tired. Often symptoms come and go.
Bowel-associated dermatosis–arthritis syndrome (BADAS), is a complication of jejunoileal bypass surgery consisting of flu-like symptoms, multiple painful joints (polyarthralgia), muscle aches (myalgia) and skin changes. It has been reported to occur in up to 20% of patients who had jejunoileal bypass surgery, a form of obesity surgery that is rarely performed today.
Going to Blazes is a short animated film, and one of many starring Oswald the Lucky Rabbit. The film is the 70th Oswald short by Walter Lantz Productions, and the 122nd in the entire series.
