List of ministers of labour and social insurance of the Republic of Cyprus since the independence in 1960:
| Minister | Began | Ended |
|---|---|---|
| Polykarpos Yiorkatzis | 5 May, 1960 | 15 August, 1960 |
| Tassos Papadopoulos | 16 August, 1960 | 24 June, 1970 |
| Andreas Mavrommatis | 1 July, 1970 | 15 June, 1972 |
| Markos Spanos | 16 June, 1972 | 15 July, 1974 |
| Panicos Sivitanides | 08 August, 1974 | 15 January, 1975 |
| Markos Spanos (2nd term) | 15 January, 1975 | 8 March, 1978 |
| Emilios Theodoulou | 9 March, 1978 | 9 September, 1980 |
| Georgios Stavrinakis | 10 September, 1980 | 19 April, 1982 |
| Pavlos Papageorgiou | 20 April, 1982 | 6 January, 1985 |
| Andreas Moushiouttas | 7 January, 1985 | 28 February, 1988 |
| Takis Hristifedes | 29 February, 1988 | 3 May, 1990 |
| Iacovos Aristidou | 4 May, 1990 | 27 February, 1993 |
| Andreas Moushouttas | 28 February, 1993 | 10 November, 1997 |
| Evstathios Papadakis | 11 November, 1997 | 27 February, 1998 |
| Andreas Moushouttas | 28 February, 1998 | 28 February, 2003 |
| Makis Keravnos | 3 March, 2003 | 18 May, 2004 |
| Christos Taliadoros | 19 May, 2004 | 8 May, 2006 |
| Antonis Vassiliou | 9 May, 2006 | 29 February, 2008 |
| Sotiroula Charalambous | 1 March 2008 | 3 April 2013 |
| Zeta Emilianidou | 3 April 2013 | 6 June 2022 |
| Kyriakos Kousios | 27 June 2022 | 28 February 2023 |
| Giannis Panayiotou | 1 March 2023 |