The First Secretary of the Nakhichevan regional branch of the Azerbaijan Communist Party was the position of highest authority in the Nakhichevan ASSR in the Azerbaijan SSR of the Soviet Union. The position was created in 1920, and abolished in August 1991. The First Secretary was a de facto appointed position usually by the Central Committee the Azerbaijan Communist Party or the First Secretary of the Republic.
| Name | Term of Office | Life years | |
|---|---|---|---|
| Start | End | ||
| First Secretaries of the Communist Party | |||
| ? | 1920 | 1921 | |
| Bagatur Velibekov | 1921 | 1921 | 1894–1938 |
| ? | 1921 | 1925 | |
| Alesker Shakhbazov | 1925 | ? | 1888–1973 |
| Ali Dzharov | ? | ? | |
| Vasily Volkov | 1929 | 1929 | 1889–1939 |
| ? | 1929 | 1933 | |
| Bagatur Velibekov | ? | 1933 | 1894–1938 |
| Ali Mamedov | 1933 | 1933 | |
| Mekhti Mekhtiyev | 1935? | December 1936 | ?–1937 |
| Gasan Rakhmanov | ? | 1937 | |
| Kyazim Ismailov | 1938? | 1940 | |
| Huseyn Nadzhafov | 1940 | 1949 | |
| Yusif Yusifov | 1949 | 1952? | |
| Pasha Aliev | 1952 | 1952 | |
| Ismail Askerov | 1952 | 1956 | 1914– |
| Khurshud Mamedov | 1956 | 1961 | 1906–? |
| Gadzhi Ibragimov | October 1961 | April 1970 | 1923– |
| Aslan Guseynov | April 1970 | December 1975 | 1916– |
| Kamran Ragimov | December 1975 | December 1983 | 1928– |
| Nuradin Mustafayev | December 1983 | November 1988 | 1942– |
| Heidar Isayev | November 1988 | January 1990 | 1936– |
| Afetdin Dzhalilov | January 1990 | April 1991 | 1946–1994 |
| Akper Aliyev | April 1989 | August 1991 | 1950– |