Combination of | |
---|---|
Ocrelizumab | Monoclonal antibody |
Hyaluronidase | Endoglycosidase |
Clinical data | |
Trade names | Ocrevus Zunovo |
AHFS/Drugs.com | Ocrevus-zunovo |
License data | |
Routes of administration | Subcutaneous |
ATC code |
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Legal status | |
Legal status |
Ocrelizumab/hyaluronidase, sold under the brand name Ocrevus Zunovo, is a fixed-dose combination medication used for the treatment of multiple sclerosis. [1] It contains ocrelizumab, a recombinant humanized monoclonal antibody directed at CD20; [1] and hyaluronidase (human recombinant), an endoglycosidase. [1] It is taken by subcutaneous injection. [1]
Ocrelizumab/hyaluronidase was approved for medical use in the United States in September 2024. [2] [3]
Ocrelizumab/hyaluronidase is indicated for the treatment of relapsing forms of multiple sclerosis, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease; [1] and primary progressive multiple sclerosis. [1]