Olmesartan/hydrochlorothiazide

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Olmesartan/hydrochlorothiazide
Combination of
Hydrochlorothiazide Thiazide diuretic
Olmesartan Angiotension receptor blocker
Clinical data
Trade names Benicar HCT, Benitec H, others
AHFS/Drugs.com Micromedex Detailed Consumer Information
License data
Routes of
administration
By mouth
ATC code
Legal status
Legal status
Identifiers
CAS Number
KEGG

Olmesartan/hydrochlorothiazide, sold under the brand name Benicar HCT among others, is a medication used to treat high blood pressure. [1] [2] It is a combination of olmesartan, an angiotension receptor blocker and hydrochlorothiazide, a diuretic. [2] It may be used if olmesartan is not sufficient to manage blood pressure. [3] It is taken by mouth. [3]

Common side effects include nausea, dizziness, and upper respiratory tract infections. [1] Serious side effects may include kidney problems, allergic reactions, electrolyte problems and low blood pressure. [1] Use in pregnancy is not recommended. [1] Olmesartan works by blocking the effects of angiotensin II while hydrochlorothiazide works by increasing the loss of sodium by the kidneys. [1]

No generic version is available in the United States as of 2017. [2] In 2020, it was the 281st most commonly prescribed medication in the United States, with more than 1 million prescriptions. [4] [5]

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References

  1. 1 2 3 4 5 6 "Benicar HCT- olmesartan medoxomil-hydrochlorothiazide tablet, film coated". DailyMed. 7 September 2022. Retrieved 3 January 2023.
  2. 1 2 3 Bope ET, Kellerman RD (2016). Conn's Current Therapy 2017 E-Book. Elsevier Health Sciences. p. 124. ISBN   9780323443357.
  3. 1 2 British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. pp. 177–178. ISBN   9780857113382.
  4. "The Top 300 of 2020". ClinCalc. Retrieved 7 October 2022.
  5. "Hydrochlorothiazide; Olmesartan - Drug Usage Statistics". ClinCalc. Retrieved 7 October 2022.