Opio may refer to:
- Opio, Alpes-Maritimes, France
- Opio (rapper), an American rapper
- Opio (surname)
- Opium , a 1949 Mexican film whose original Spanish title is Opio
- "Opio", a song by Hieroglyphics on the album 3rd Eye Vision
This disambiguation page lists articles associated with the title Opio.
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