Rob Horne is Professor of Behavioural Medicine at the School of Pharmacy, University College London (UCL). [1] In September 2006, he founded the Centre for Behavioural Medicine at UCL, which he continues to lead. [1] Horne was designated a Fellow of the Royal College of Physicians Faculty of Pharmaceutical Medicine in 2013 [2] and is a founding fellow of the Royal Pharmaceutical Society of Great Britain. [3] He was appointed as a National Institute for Health Research (NIHR) Senior Investigator in 2011. [3] He is an internationally recognised expert in self-management of chronic illness and adherence to medications. [4]
Horne qualified as a pharmacist and has a PhD in medical psychology from King's College London. [5] Before joining UCL, Horne was Professor of Psychology in Health Care and Director of the Centre for Health Care Research at the University of Brighton. [5] Horne founded and is Director of the Centre for Behavioural Medicine, which is part of the UCL School of Pharmacy. The overall aim of the Centre is to make healthcare more efficient by understanding and addressing the psychological and behavioural factors explaining variation in response to treatment. [5]
Horne's academic research focuses on the role of psychological and behavioural factors in explaining the variation in patients’ response to medication. [3] He has developed a range of tools and models for assessing patients’ perspectives of illness and treatment e.g. the Beliefs about Medicines Questionnaire (BMQ) and Medication Adherence Report (MARS) as well as frameworks for understanding treatment-related behaviours with a particular focus on adherence to medication e.g. the Necessity-Concerns Framework and Perceptions and Practicalities approach. [3] [6] To date, these tools have been validated in the following long-term medical conditions: renal dialysis; renal transplantation; asthma; cancer; coronary heart disease; hypertension; diabetes; HIV/AIDS; haemophilia; depression; bipolar disorder; rheumatoid arthritis; inflammatory bowel disease and also for newly prescribed medications in primary care. [7] [8] [9] [10] [11] [12] [13] [14] [15] [16] [17] His current research focuses on the development of theory-based interventions to support informed choice and optimal adherence to medication or other treatments in chronic illness. Other research interests include emotion and health and the placebo effect. [18] Over the past decade, his research has generated over 140 peer-reviewed publications and book chapters, and grants over £7 million. [1]
Horne and his research team regularly contribute to UK and international reports and guidelines on adherence, and to consultancy for national charities, the NHS and commercial health organisations. [3] Professor Horne’s recent contributions to health policy include adherence guidelines for the National Institute for Health and Clinical Excellence (NICE) published in 2009 [19] and a report for the National Co-ordinating Centre for NHS Service Delivery and Organisation R&D (NCCSDO) published in 2005. [20]
In November 2011, Horne co-founded a UCLBusiness spinout company. [21] [22] The company, called Spoonful of Sugar, applies Horne's research to behavioural change consultancy, evidence-based adherence support, validated behavioural research and perspectives mapping and personalised communications. [22]
Horne is an Academic Fellow of the Centre for the Advancement of Sustainable Medical Innovation (CASMI), a partnership between Oxford University and UCL created to develop new models for medical innovation. [23] In November 2012, Horne was appointed as UCL's academic lead for CASMI. [5]
Asthma is a long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. These may occur a few times a day or a few times per week. Depending on the person, asthma symptoms may become worse at night or with exercise.
Activities of daily living is a term used in healthcare to refer to people's daily self-care activities. Health professionals often use a person's ability or inability to perform ADLs as a measurement of their functional status. The concept of ADLs was originally proposed in the 1950s by Sidney Katz and his team at the Benjamin Rose Hospital in Cleveland, Ohio. The concept of ADLs has been added to and refined by a variety of researchers since that time. For example, many indexes that assess ADLs now include some measure of mobility. Additionally, to be more inclusive of the range of activities that support independent living, in 1969, Lawton and Brody developed the instrumental activities of daily living (IADLs). ADLs are often used in the care of people with disabilities, people with injuries, and elderly people. Younger children often require help from adults to perform ADLs, as they have not yet developed the skills necessary to perform them independently.
Palliative care is an interdisciplinary medical caregiving approach aimed at optimizing quality of life and mitigating suffering among people with serious, complex, and often terminal illnesses. Within the published literature, many definitions of palliative care exist. The World Health Organization (WHO) describes palliative care as "an approach that improves the quality of life of patients and their families facing the problems associated with life-threatening illness, through the prevention and relief of suffering by means of early identification and impeccable assessment and treatment of pain and other problems, physical, psychosocial, and spiritual". In the past, palliative care was a disease specific approach, but today the WHO takes a broader patient-centered approach that suggests that the principles of palliative care should be applied as early as possible to any chronic and ultimately fatal illness. This shift was important because if a disease-oriented approach is followed, the needs and preferences of the patient are not fully met and aspects of care, such as pain, quality of life, and social support, as well as spiritual and emotional needs, fail to be addressed. Rather, a patient-centered model prioritizes relief of suffering and tailors care to increase the quality of life for terminally ill patients.
Ambulatory care or outpatient care is medical care provided on an outpatient basis, including diagnosis, observation, consultation, treatment, intervention, and rehabilitation services. This care can include advanced medical technology and procedures even when provided outside of hospitals.
Pain management is an aspect of medicine and health care involving relief of pain in various dimensions, from acute and simple to chronic and challenging. Most physicians and other health professionals provide some pain control in the normal course of their practice, and for the more complex instances of pain, they also call on additional help from a specific medical specialty devoted to pain, which is called pain medicine.
Polypharmacy (polypragmasia) is an umbrella term to describe the simultaneous use of multiple medicines by a patient for their conditions. Most commonly it is defined as regularly taking five or more medicines but definitions vary in where they draw the line for the minimum number of drugs. Polypharmacy is often the consequence of having multiple long-term conditions, also known as multimorbidity. An excessive number of medications is worrisome, especially for older patients with many chronic health conditions, because this increases the risk of an adverse event in those patients.
In medicine, patient compliance describes the degree to which a patient correctly follows medical advice. Most commonly, it refers to medication or drug compliance, but it can also apply to other situations such as medical device use, self care, self-directed exercises, or therapy sessions. Both patient and health-care provider affect compliance, and a positive physician-patient relationship is the most important factor in improving compliance. Access to care plays a role in patient adherence, whereby greater wait times to access care contributing to greater absenteeism. The cost of prescription medication also plays a major role.
Pharmacotherapy, also known as pharmacological therapy or drug therapy, is defined as medical treatment that utilizes one or more pharmaceutical drugs to improve on-going symptoms, treat the underlying condition, or act as a prevention for other diseases (prophylaxis).
Mental disorders are classified as a psychological condition marked primarily by sufficient disorganization of personality, mind, and emotions to seriously impair the normal psychological and often social functioning of the individual. Individuals diagnosed with certain mental disorders can be unable to function normally in society. Mental disorders may consist of several affective, behavioral, cognitive and perceptual components. The acknowledgement and understanding of mental health conditions has changed over time and across cultures. There are still variations in the definition, classification, and treatment of mental disorders.
Self-care has been defined as the process of establishing behaviors to ensure holistic well-being of oneself, to promote health, and actively manage illness when it occurs. Individuals engage in some form of self-care daily with food choices, exercise, sleep, reading and dental care. Self-care is not only a solo activity as the community—a group that supports the person performing self-care—overall plays a large role in access to, implementation of, and success of self-care activities.
Multimorbidity, also known as multiple long-term conditions (MLTC), means living with two or more chronic illnesses. For example, a person could have diabetes, heart disease and depression at the same time. Multimorbidity can have a significant impact on people's health and wellbeing. It also poses a complex challenge to healthcare systems which are traditionally focused on individual diseases. Multiple long-term conditions are much more common in older people, affecting more than half of those over 65, however, they can also be found in young people.
A caregiver, carer or support worker is a paid or unpaid member of a person's social network who helps them with activities of daily living. Since they have no specific professional training, they are often described as informal caregivers. Caregivers most commonly assist with impairments related to old age, disability, a disease, or a mental disorder.
The health management system (HMS) is an evolutionary medicine regulative process proposed by Nicholas Humphrey in which actuarial assessment of fitness and economic-type cost–benefit analysis determine the body’s regulation of its physiology and health. The incorporation of the cost–benefit calculations into body regulation provides a science grounded approach to mind–body phenomena such as placebos, are otherwise not explainable by low level, noneconomic, and purely feedback based homeostatic or allostatic theories.
Functional disorder is an umbrella term for a group of recognisable medical conditions which are due to changes to the functioning of the systems of the body rather than due to a disease affecting the structure of the body.
Minimally disruptive medicine is an approach to patient care in chronic illness proposed by Carl R May, Victor Montori, and Frances Mair. In a 2009 article in the British Medical Journal they argued that the burden of illness has its counterpart in the burden of treatment. As medical responses to illness have become more sophisticated, the burden of treatment has grown, and includes increasingly complex techniques and health technologies that must be routinely incorporated in everyday life by their users. minimally disruptive medicine is an approach to designing patient care that seeks to consider the effects of treatment work, and in particular to prevent overburdening patients. Overburdening leads, May, Montori and Mair argued, to structurally induced non-compliance with treatment, in which it becomes progressively more difficult for patients – especially older patients with multiple long-term conditions – to meet the demands that therapeutic regimens place upon them. minimally disruptive medicine has a theoretical basis in Normalization Process Theory, which explains the processes by which treatment regimens and other ensembles of cognitive, behavioural and technical practices are routinely incorporated in everyday life.
Traditional African medicine is a range of traditional medicine disciplines involving indigenous herbalism and African spirituality, typically including diviners, midwives, and herbalists. Practitioners of traditional African medicine claim, largely without evidence, to be able to cure a variety of diverse conditions including cancer, psychiatric disorders, high blood pressure, cholera, most venereal diseases, epilepsy, asthma, eczema, fever, anxiety, depression, benign prostatic hyperplasia, urinary tract infections, gout, and healing of wounds and burns and even Ebola.
Pediatric psychology is a multidisciplinary field of both scientific research and clinical practice which attempts to address the psychological aspects of illness, injury, and the promotion of health behaviors in children, adolescents, and families in a pediatric health setting. Psychological issues are addressed in a developmental framework and emphasize the dynamic relationships which exist between children, their families, and the health delivery system as a whole.
Deprescribing is described as a patient-centred process to taper or stop medications with the intention to achieve improved health outcomes by reducing exposure to medications that are potentially either harmful or no longer required. Deprescribing is important to consider with changing health and care goals over time, as well as polypharmacy and adverse effects. Deprescribing can improve adherence, cost, and health outcomes but may have adverse drug withdrawal effects. More specifically, deprescribing is the planned and supervised process of intentionally stopping a medication or reducing its dose to improve the person's health or reduce the risk of adverse side effects. Deprescribing is usually done because the drug may be causing harm, may no longer be helping the patient, or may be inappropriate for the individual patient's current situation. Deprescribing can help correct polypharmacy and prescription cascade.
John Alfred Weinman is a British psychologist who has been prominent in the development of the field of health psychology.
The taxonomy of the burden of treatment is a visualization created for health care professionals to better comprehend the obstacles that interfere with a patient's health care plan. It was created as a result of a world wide, qualitative-based study that asked adults with chronic conditions to list the personal, environmental, and financial barriers that burden a patient. The purpose of this visualization is to help health care providers develop personalized management strategies that the patient can follow through a narrative paradigm. The goal is to target interventions, achieve an interpersonal doctor-patient relationship, and improve health outcomes.
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