Snake H/ACA box small nucleolar RNA

Last updated
Snake H/ACA box small nucleolar RNA
RF00098.jpg
Identifiers
SymbolHACA_sno_Snake
Rfam RF00098
Other data
RNA typeGene;snRNA;snoRNA;H/ACA-box;
PDB structures PDBe

In molecular biology, Snake H/ACA box small nucleolar RNA refers to a number of very closely related non-coding RNA (ncRNA) genes identified in snakes which have been predicted to be small nucleolar RNAs (snoRNAs). This type of ncRNA is involved in the biogenesis of other small nuclear RNAs and are often referred to as 'guide' RNAs. They are usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.

These snoRNA genes were initially identified in the introns of the cardiotoxin 4 and cobrotoxin genes of the Taiwan cobra ( Bungarus multicinctus ) and the Taiwan banded krait ( Bungarus multicinctus ) during sequencing of these genes. [1] [2] These snoRNAs are predicted to act as H/ACA box type methylation guides as they have the predicted hairpin-hinge-hairpin-tail structure and extended regions of complementarity to 5S ribosomal RNA (rRNA). [3]

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Small nucleolar RNA SNORA46

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Small nucleolar RNA SNORA50

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Small nucleolar RNA SNORA52

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Small nucleolar RNA SNORA55

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Small nucleolar RNA SNORA56

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Small nucleolar RNA SNORA57

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Small nucleolar RNA SNORA61

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Small nucleolar RNA SNORA65

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Small nucleolar RNA SNORA66

In molecular biology, SNORA66 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA". U66 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. U66 is predicted to guide the pseudouridylation of U119 of 18S ribosomal RNA (rRNA). Pseudouridylation is the to the different isomeric form pseudouridine.

Small nucleolar RNA SNORA68

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Small nucleolar RNA SNORA69

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Small nucleolar RNA SNORA72

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Small nucleolar RNA SNORD86

In molecular biology, Small nucleolar RNA SNORD86 is a non-coding RNA (ncRNA) that belongs to the C/D family of snoRNAs. It is the human orthologue of Xenopus laevis U86 and has no identified RNA target. The snoRNAs U86, U56, U57 and HBII-55,of the C/D family, and the H/ACA box snoRNA ACA51 share the same host gene (NOL5A) with U86.

Small nucleolar RNA SNORA70

In molecular biology, Small nucleolar RNA SNORA70 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".

Small nucleolar RNA SNORA11

In molecular biology, Small nucleolar RNA SNORA11 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA).

Small nucleolar RNA SNORA77

In molecular biology, Small nucleolar RNA SNORA77 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA).

References

  1. Chang, Long-Sen; Lin, Shu-Kai; Wu, Pei-Fung (17 April 1998). "Differentially expressed snoRNAs in Bungarus multicinctus (Taiwan banded krait)". Biochemical and Biophysical Research Communications . 245 (2): 397–402. doi:10.1006/bbrc.1998.8433. PMID   9571162.
  2. Chang, Long-Sen; Hong, Enjong (30 July 1997). "Novel SnoRNAs from Naja naja atra (Taiwan cobra) and Bungarus multicinctus (Taiwan banded krait) form extended sequence complementarity to 5S rRNA". Biochemical and Biophysical Research Communications . 236 (3): 782–784. doi:10.1006/bbrc.1997.7049. PMID   9245733.
  3. Ganot, Philippe; Caizergues-Ferrer, Michèle; Kiss, Tamás (1 April 1997). "The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation". Genes & Development . 11 (7): 941–956. doi: 10.1101/gad.11.7.941 . PMID   9106664.