TRNA pseudouridine38/39 synthase

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tRNA pseudouridine38/39 synthase
Identifiers
EC no. 5.4.99.45
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tRNA pseudouridine38/39 synthase (EC 5.4.99.45, Deg1, Pus3p, pseudouridine synthase 3) is an enzyme with systematic name tRNA-uridine38/39 uracil mutase. [1] [2] This enzyme catalyses the following chemical reaction

Contents

tRNA uridine 38/39 tRNA pseudouridine38/39

The enzyme from Saccharomyces cerevisiae is active only towards uridine38 and uridine39.

See also

Related Research Articles

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References

  1. Lecointe F, Simos G, Sauer A, Hurt EC, Motorin Y, Grosjean H (January 1998). "Characterization of yeast protein Deg1 as pseudouridine synthase (Pus3) catalyzing the formation of psi 38 and psi 39 in tRNA anticodon loop". The Journal of Biological Chemistry. 273 (3): 1316–23. doi: 10.1074/jbc.273.3.1316 . PMID   9430663.
  2. Chen J, Patton JR (October 2000). "Pseudouridine synthase 3 from mouse modifies the anticodon loop of tRNA". Biochemistry. 39 (41): 12723–30. doi:10.1021/bi001109m. PMID   11027153.