Testosterone propionate/testosterone enanthate/testosterone undecylenate

Last updated
TP/TE/TUe
Combination of
Testosterone propionate Androgen; Anabolic steroid
Testosterone enanthate Androgen; Anabolic steroid
Testosterone undecylenate Androgen; Anabolic steroid
Clinical data
Trade names Durasteron
Other namesTP/TE/TUe
Routes of
administration
Intramuscular injection

Testosterone propionate/testosterone enanthate/testosterone undecylenate (TP/TE/TUe), sold under the brand name Durasteron, is an injectable combination medication of testosterone propionate (TP), testosterone valerate (TV), and testosterone undecylenate (TUe), all of which are androgens/anabolic steroids. [1] [2] It contains 20 mg TP, 80 mg TE, and 150 mg TUe (for a total of 250 mg testosterone ester and 169.5 mg free testosterone) in oil solution and is administered by intramuscular injection at regular intervals, for instance once every 3 or 4 weeks. [3] [4] [5] Use of Durasteron by bodybuilders has been reported. [1] [2]

Parenteral durations of androgens/anabolic steroids
MedicationFormMajor brand namesDuration
Testosterone Aqueous suspensionAndronaq, Sterotate, Virosterone2–3 days
Testosterone propionate Oil solutionAndroteston, Perandren, Testoviron3–4 days
Testosterone phenylpropionate Oil solutionTestolent8 days
Testosterone isobutyrate Aqueous suspensionAgovirin Depot, Perandren M14 days
Mixed testosterone esters aOil solutionTriolandren10–20 days
Mixed testosterone esters bOil solutionTestosid Depot14–20 days
Testosterone enanthate Oil solutionDelatestryl14–28 days
Testosterone cypionate Oil solutionDepovirin14–28 days
Mixed testosterone esters cOil solutionSustanon 25028 days
Testosterone undecanoate Oil solutionAveed, Nebido100 days
Testosterone buciclate dAqueous suspension20 Aet-1, CDB-1781e90–120 days
Nandrolone phenylpropionate Oil solutionDurabolin10 days
Nandrolone decanoate Oil solutionDeca Durabolin21–28 days
Methandriol Aqueous suspensionNotandron, Protandren8 days
Methandriol bisenanthoyl acetate Oil solutionNotandron Depot16 days
Metenolone acetate Oil solutionPrimobolan3 days
Metenolone enanthate Oil solutionPrimobolan Depot14 days
Note: All are via i.m. injection. Footnotes:a = TP, TV, and TUe. b = TP and TKL. c = TP, TPP, TiCa, and TD. d = Studied but never marketed. e = Developmental code names. Sources: See template.

See also

Related Research Articles

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Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone decanoate (TP/TPP/TiC/TD), also known as a Sustanon 250 (Organon), is an injectable combination medication of four testosterone esters, all of which are androgens/anabolic steroids.

<span class="mw-page-title-main">Nandrolone decanoate</span> Anabolic steroid

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<span class="mw-page-title-main">Testosterone propionate</span> Chemical compound

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<span class="mw-page-title-main">Estradiol dienantate</span>

Estradiol dienanthate (EDE), sold under the brand names Climacteron among others, is a long-acting estrogen medication which was previously used in menopausal hormone therapy for women and to suppress lactation in women. It was formulated in combination with estradiol benzoate (EB), a short-acting estrogen, and testosterone enanthate benzilic acid hydrazone (TEBH), a long-acting androgen/anabolic steroid. EDE has not been made available for medical use alone. The medication, in combination with EB and TEBH, was given by injection into muscle once or at regular intervals, for instance once every 6 weeks.

<span class="mw-page-title-main">Testosterone isobutyrate</span> Chemical compound

Testosterone isobutyrate, sold under the brand names Agovirin-Depot and Perandren M among others, is an androgen and anabolic steroid medication and a testosterone ester which is used for indications such as low testosterone levels in men and delayed puberty in boys. It is available only in the Czech Republic and Slovakia. The medication is administered by injection into muscle once every 1 to 2 weeks in males. Unlike most other testosterone esters, which are provided as oil solutions, testosterone isobutyrate is formulated as a microcrystalline aqueous suspension.

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<span class="mw-page-title-main">Testosterone valerate</span> Chemical compound

Testosterone valerate, or testosterone pentanoate, also known as androst-4-en-17β-ol-3-one 17β-valerate, is a synthetic, steroidal androgen and an androgen ester – specifically, the C17β valerate ester of testosterone – which is used in veterinary medicine. It is administered via intramuscular injection and acts as a long-lasting prodrug of testosterone. The medication is available as a component of the veterinary drug Deposterona, which is marketed in Mexico and also contains testosterone acetate and testosterone undecanoate. Testosterone valerate is a short-to-medium duration ester of testosterone, with an elimination half-life of approximately twice that of the short-acting testosterone propionate.

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<span class="mw-page-title-main">Estradiol valerate/testosterone enanthate</span>

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Estradiol benzoate/estradiol phenylpropionate/testosterone propionate/testosterone phenylpropionate/testosterone isocaproate (EB/EPP/TP/TPP/TiC), sold under the brand names Estandron Prolongatum, Lynandron Prolongatum, and Mixogen, was an injectable combination medication of the estrogens estradiol benzoate (EB) and estradiol phenylpropionate (EPP) and the androgens/anabolic steroids testosterone propionate (TP), testosterone phenylpropionate (TPP), and testosterone isocaproate (TiC) which was used in menopausal hormone therapy for women. It was also used to suppress lactation in postpartum women.

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<span class="mw-page-title-main">Testosterone propionate/testosterone ketolaurate</span> Combination drug

Testosterone propionate/testosterone ketolaurate (TP/TKL), sold under the brand name Testosid-Depot, is an injectable combination medication of testosterone propionate (TP), an androgen/anabolic steroid, and testosterone ketolaurate, an androgen/anabolic steroid. It contains 25 mg TP and 150 to 300 mg TKL in oil solution and is administered by intramuscular injection at regular intervals. The medication has been reported to have a duration of action of about 14 to 20 days.

<span class="mw-page-title-main">Testosterone undecylenate</span>

Testosterone undecylenate (TUe) is an androgen/anabolic steroid medication and androgen ester which is no longer marketed. It was a component of Durasteron and Triolandren, long-acting mixtures of testosterone esters in oil solution that were administered by intramuscular injection.

Testosterone propionate/testosterone cypionate/prasterone (TP/TC/DHEA), sold under the brand name Sten, is an injectable combination medication of testosterone propionate (TP), a fast-acting androgen/anabolic steroid, testosterone cypionate (TC), a long-acting androgen/anabolic steroid, and prasterone, an androgen and neurosteroid, which has been used to treat andropause, hypogonadism, and impotence in men and breast cancer, fibrocystic breast disease, and low sexual desire in women. It contains 25 mg TP, 75 mg TC, and 20 mg DHEA in 2 mL oil solution provided in ampoules and is administered by intramuscular injection once every 15 to 30 days. The medication was previously marketed in Mexico but appears to no longer available. The duration of action of TP/TC/DHEA has been reported to be approximately 15 to 30 days, due to the long-acting TC component.

Estradiol benzoate/progesterone/testosterone propionate (EB/P4/TP), sold under the brand names Lukestra, Steratrin, Trihormonal, and Trinestryl, is an injectable combination medication of estradiol benzoate (EB), an estrogen, progesterone (P4), a progestogen, and testosterone propionate (TP), an androgen/anabolic steroid. It contained 1 to 3 mg EB, 20 to 25 mg P4, and 25 mg TP, was provided in the form of ampoules, and was administered by intramuscular injection. The medication was introduced by 1949 and was marketed in the United States, the United Kingdom, and Germany among other places. It is no longer available.

References

  1. 1 2 Daher EF, Silva Júnior GB, Queiroz AL, Ramos LM, Santos SQ, Barreto DM, et al. (2009). "Acute kidney injury due to anabolic steroid and vitamin supplement abuse: report of two cases and a literature review". International Urology and Nephrology. 41 (3): 717–23. doi:10.1007/s11255-009-9571-8. PMID   19387860. S2CID   23319246.
  2. 1 2 Davani-Davari D, Karimzadeh I, Khalili H (May 2019). "The potential effects of anabolic-androgenic steroids and growth hormone as commonly used sport supplements on the kidney: a systematic review". BMC Nephrology. 20 (1): 198. doi: 10.1186/s12882-019-1384-0 . PMC   6545019 . PMID   31151420.
  3. Joël, Charles A. (1960). "Zur Behandlung männlicher Fertilitätsstörungen mit hohen Androgendosen" [For the treatment of male fertility disorders with high androgen doses]. Gynecologic and Obstetric Investigation. 150 (3): 149–156. doi:10.1159/000305737. ISSN   1423-002X. [...] 20 mg Testosteronpropionat, 80 mg Testosteronheptanoat, 150 mg Testosteronundecylat (Durasteron Teva) [...]
  4. Arends G, Zörnig H, Hager H, Frerichs G, Kern W (14 December 2013). Hagers Handbuch der pharmazeutischen Praxis: Für Apotheker, Arzneimittelhersteller, Drogisten, Ärzte u. Medizinalbeamte. Springer-Verlag. pp. 1145–. ISBN   978-3-662-36329-4. At the same time, treatment with a long-acting testosterone preparation (Durasteron®) was instituted, with one injection given every four weeks.
  5. Spitz IM, Hirsch HJ, Landau H, Zylber-Haran E, Gross V, Rachmilewitz EA (October 1984). "TSH secretion in thalassemia". Journal of Endocrinological Investigation. 7 (5): 495–9. doi:10.1007/BF03348456. PMID   6439771. S2CID   20319052. The male patients were given a long acting tes- tosterone preparation (Durasteron, Teva) 250 mg by im injection every 3 weeks for a total of 8 injections.