Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone decanoate

TP/TPP/TiC/TD

Combination of
Testosterone propionate	Androgen; Anabolic steroid
Testosterone phenylpropionate	Androgen; Anabolic steroid
Testosterone isocaproate	Androgen; Anabolic steroid
Testosterone decanoate	Androgen; Anabolic steroid
Clinical data
Trade names	Durandrone Forte, Durateston, Prarbolan, Sustanon 250, Sustanon Prolongatum
Other names	TP/TPP/TiC/TD
Routes of administration	Intramuscular injection
Identifiers
CAS Number	57-85-2  Y 1255-49-8  Y
PubChem CID	155142
ChemSpider	136679
UNII	WI93Z9138A 8GN84GWX51  Y

Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone decanoate (TP/TPP/TiC/TD), also known as a Sustanon 250 (Organon), is an injectable combination medication of four testosterone esters, all of which are androgens/anabolic steroids. ^[1]

Pharmacology

The four testosterone esters are as follows;

• 30 mg testosterone propionate ^[1]
• 60 mg testosterone phenylpropionate ^[1]
• 60 mg testosterone isocaproate ^[1]
• 100 mg testosterone decanoate ^[1]

Cumulatively, a 1 ml of the oil solution contains exactly 250 mg of above mentioned testosterone esters. ^{[2] [3]} This particular numerical value is clearly depicted in the name of the product, Sustanon 250. ^[4]

They are provided as an oil solution and are administered by intramuscular injection. ^[5] The different testosterone esters provide for different elimination half-lives in the body. Esterification of testosterone provides for a sustained but non-linear release of testosterone hormone from the injection depot into the circulation. Sustanon 100 is administered once every 2 weeks and Sustanon 250 is administered once every 3 to 4 weeks. ^[6]

Sustanon is the preferred method of testosterone replacement in the United Kingdom as detailed in the British National Formulary.^{[ citation needed ]} There was a brief shortage of Sustanon 250 during late 2011, due to shifting of manufacturing site, ^[7] and a further shortage in mid-2012 due to manufacturing problems.^{[ medical citation needed ]}

This form of testosterone has long been a popular choice of anabolic steroid among bodybuilders while bulking.^{[ citation needed ]}

Synonyms/brands

• Durateston
• Durandrone Forte
• Sustanon prolongatum
• Prarbolan

See also

• Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate
• Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone caproate
• List of combined sex-hormonal preparations § Androgens

References

1. PubChem. "Sustanon 250". pubchem.ncbi.nlm.nih.gov. Retrieved 2020-09-06.
2. "NEW ZEALAND DATA SHEET-SUSTANON 250 (250 mg testosterone esters solution for injection)" (PDF). Medsafe, Ministry of Health (New Zealand). 18 June 2020.
3. "Detailed description of the steroid drug Sustanon 250". Secrets of bodybuilding and muscles training. 2020-02-05. Retrieved 2020-09-06.
4. "Sustanon 250 Online | 100% Real" . Retrieved 2021-01-21.
5. Area Prescribing Committee, Nottinghamshire (January 2020). "ADMINISTRATION GUIDE FOR TESTOSTERONE SUSTANON-250" (PDF). National Health Service.
6. Llewellyn W (2011). Anabolics. Molecular Nutrition Llc. pp. 392–398. ISBN   978-0-9828280-1-4.
7. MEDICINES MANAGEMENT COMMITTEE, HERTFORDSHIRE (November 2011). "Testosterone undecanoate (Nebido) is recommended as an option for testosterone replacement therapy ONLY whilst Sustanon 250 and Testosterone Enantate (Nonproprietary) are unavailable" (PDF). National Health Service.