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Bioterrorism is terrorism involving the intentional release or dissemination of biological agents. These agents include bacteria, viruses, insects, fungi, and/or their toxins, and may be in a naturally occurring or a human-modified form, in much the same way as in biological warfare. Further, modern agribusiness is vulnerable to anti-agricultural attacks by terrorists, and such attacks can seriously damage economy as well as consumer confidence. The latter destructive activity is called agrobioterrorism and is a subtype of agro-terrorism.
A pandemic is an epidemic of an infectious disease that has a sudden increase in cases and spreads across a large region, for instance multiple continents or worldwide, affecting a substantial number of individuals. Widespread endemic diseases with a stable number of infected individuals such as recurrences of seasonal influenza are generally excluded as they occur simultaneously in large regions of the globe rather than being spread worldwide.
Biodefense refers to measures to counter biological threats, reduce biological risks, and prepare for, respond to, and recover from bioincidents, whether naturally occurring, accidental, or deliberate in origin and whether impacting human, animal, plant, or environmental health. Biodefense measures often aim to improve biosecurity or biosafety. Biodefense is frequently discussed in the context of biological warfare or bioterrorism, and is generally considered a military or emergency response term.
An epidemic is the rapid spread of disease to a large number of hosts in a given population within a short period of time. For example, in meningococcal infections, an attack rate in excess of 15 cases per 100,000 people for two consecutive weeks is considered an epidemic.
Avian influenza, also known as avian flu or bird flu, is a disease caused by the influenza A virus, which primarily affects birds but can sometimes affect mammals including humans. Wild aquatic birds are the primary host of the influenza A virus, which is endemic in many bird populations.
Influenza A virus subtype H5N1 (A/H5N1) is a subtype of the influenza A virus, which causes influenza (flu), predominantly in birds. It is enzootic in many bird populations, and also panzootic. A/H5N1 virus can also infect mammals that have been exposed to infected birds; in these cases, symptoms are frequently severe or fatal.
An influenza pandemic is an epidemic of an influenza virus that spreads across a large region and infects a large proportion of the population. There have been six major influenza epidemics in the last 140 years, with the 1918 flu pandemic being the most severe; this is estimated to have been responsible for the deaths of 50–100 million people. The 2009 swine flu pandemic resulted in under 300,000 deaths and is considered relatively mild. These pandemics occur irregularly.
Michael Thomas Osterholm is an American epidemiologist, Regents Professor at the University of Minnesota School of Public Health, and director of the Center for Infectious Disease Research and Policy at the University of Minnesota.
Disease surveillance is an epidemiological practice by which the spread of disease is monitored in order to establish patterns of progression. The main role of disease surveillance is to predict, observe, and minimize the harm caused by outbreak, epidemic, and pandemic situations, as well as increase knowledge about which factors contribute to such circumstances. A key part of modern disease surveillance is the practice of disease case reporting.
The Biomedical Advanced Research and Development Authority (BARDA) is a U.S. Department of Health and Human Services (HHS) office responsible for the procurement and development of medical countermeasures, principally against bioterrorism, including chemical, biological, radiological and nuclear (CBRN) threats, as well as pandemic influenza and emerging diseases. BARDA was established in 2006 through the Pandemic and All-Hazards Preparedness Act (PAHPA) and reports to the Office of the Assistant Secretary for Preparedness and Response (ASPR). The office manages Project BioShield, which funds the research, development and stockpiling of vaccines and treatments that the government could use during public health emergencies such as chemical, biological, radiological or nuclear (CBRN) attacks.
On December 19, 2006, the Pandemic and All-Hazards Preparedness Act (PAHPA), Public Law No. 109-417, was signed into law by President George W. Bush. First introduced in the House by Rep. Mike Rogers (R-MI) and Rep. Anna Eshoo (D-CA), PAHPA had broad implications for the United States Department of Health and Human Services's (HHS) preparedness and response activities. Among other things, the act amended the Public Health Service Act to establish within the department a new Assistant Secretary for Preparedness and Response (ASPR); provided new authorities for a number of programs, including the advanced development and acquisitions of medical countermeasures; and called for the establishment of a quadrennial National Health Security Strategy.
The 2009 swine flu pandemic, caused by the H1N1/swine flu/influenza virus and declared by the World Health Organization (WHO) from June 2009 to August 2010, was the third recent flu pandemic involving the H1N1 virus. The first identified human case was in La Gloria, Mexico, a rural town in Veracruz. The virus appeared to be a new strain of H1N1 that resulted from a previous triple reassortment of bird, swine, and human flu viruses which further combined with a Eurasian pig flu virus, leading to the term "swine flu".
The Center for Infectious Disease Research and Policy (CIDRAP) is a center within the University of Minnesota that focuses on addressing public health preparedness and emerging infectious disease response. It was founded in 2001 by Dr. Michael Osterholm, in order to "prevent illness and death from infectious diseases through epidemiological research and rapid translation of scientific information into real-world practical applications and solutions". It is not part of the Center for Disease Control or National Institute of Health.
Ali S. Khan is an American practicing physician and former Director of the Office of Public Health Preparedness and Response (PHPR) at the Centers for Disease Control and Prevention. Since July 2014, he has served as Dean of the College of Public Health and Retired Assistant Surgeon General at the University of Nebraska Medical Center in Omaha, Nebraska.
Biosecurity in the United States is governed by the Bureau of Western Hemisphere Affairs, which is part of the US Department of State. It obtains guidance and advice on specific matters relating to biosecurity from various other government agencies.
Stephen S. Morse is an American epidemiologist, influenza researcher and specialist on emerging infectious diseases, who has served as an adviser on the epidemiology of infectious diseases and on improving disease early warning systems to numerous government and international organizations. As of 2016, he is Professor of Epidemiology at the Mailman School of Public Health of Columbia University. His seminal book Emerging Viruses (1993) was selected by American Scientist for its list of "100 Top Science Books of the 20th Century".
Stephen C. Redd is a U.S. physician and rear admiral with the U.S. Public Health Service and an Assistant Surgeon General. With over 30 years of public health and executive leadership experience, Redd served as the Director of the Office of Public Health Preparedness and Response at the Centers for Disease Control and Prevention. Previously, he was the Director of the CDC's Influenza Coordination Unit, where he served as the incident commander for the 2009-2010 H1N1 pandemic influenza response.
Health security is a concept that encompasses activities and measures across sovereign boundaries that mitigates public health incidents to ensure the health of populations. It is an evolving paradigm within the fields of international relations and security studies. Proponents of health security posit that all states have a responsibility to protect the health and wellbeing of their populations. Opponents suggest health security impacts civil liberties and the equal distribution of resources.
The 1957–1958 Asian flu pandemic was a global pandemic of influenza A virus subtype H2N2 that originated in Guizhou in Southern China. The number of excess deaths caused by the pandemic is estimated to be 1–4 million around the world, making it one of the deadliest pandemics in history. A decade later, a reassorted viral strain H3N2 further caused the Hong Kong flu pandemic (1968–1969).
Planning and preparing for pandemics has happened in countries and international organizations. The World Health Organization writes recommendations and guidelines, though there is no sustained mechanism to review countries' preparedness for epidemics and their rapid response abilities. National action depends on national governments. In 2005–2006, before the 2009 swine flu pandemic and during the decade following it, the governments in the United States, France, UK, and others managed strategic health equipment stocks, but they often reduced stocks after the 2009 pandemic in order to reduce costs.
References
- ↑ Anthony Fauci, Director, National Institute of Allergy and Infectious Diseases, National Institutes of Health, “Preparation for Avian Flu Pandemic,” Testimony before the Senate Appropriations Subcommittee on Labor, Health and Human Services, Education, and Related Agencies, 24 January 2007.
- ↑ Jeffrey Levi; Misha Segal; Laura M. Segal (March 2007). Pandemic Flu and the Potential for U.S. Economic Recession (PDF) (Report). Trust for America's Health. Archived from the original (PDF) on 8 July 2007.
- ↑ "TFAH Initiatives: Pandemic Flu". Trust for America's Health. Archived from the original on 14 October 2008.
- ↑ Mead, Paul S.; Slutsker, Laurence; et al. (September–October 1999). "Food-Related Illness and Death in the United States". Emerging Infectious Diseases. 5 (5): 607–625. doi: 10.3201/eid0505.990502 . PMC 2627714 . PMID 10511517.
- ↑ "Overweight and Obesity – Introduction". U.S. Department of Health and Human Services. Archived from the original on 19 May 2008.
- ↑ Martin, Aaron (2017-12-22). "Many state bioterrorism countermeasures are lagging, report finds". Homeland Preparedness News.
- ↑ Gordon, David (January 2000). "National Intelligence Estimate 99-17D: The Global Infectious Disease Threat and Its Implications for the United States". Washington, D.C.: The National Intelligence Council.