USS Nerka may refer to:
- USS Nerka (SS-380), a United States Navy submarine authorized during World War II; her construction contract was canceled in July 1944
- USS Nerka, a fictional World War II submarine of the United States Navy that serves as the setting for the 1958 film Run Silent, Run Deep , an adaptation of the 1955 novel of the same name.
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.