USS Octopus may refer to:
- USS Octopus (SS-9), a United States Navy submarine in commission from 1908 to 1919 and renamed USS C-1 (SS-9) in 1911
- USS Octopus, a fictional World War II United States Navy submarine in Edward L. Beach's 1955 novel Run Silent, Run Deep
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.