Hallerian physiology

Last updated

Hallerian physiology was a theory competing with galvanism in Italy in the late 18th century. It is named after Albrecht von Haller, a Swiss physician who is considered the father of neurology.

The Hallerians' fundamental tenet held that muscular movements were produced by a mechanical force, different from life and from the nervous system, and which operated beyond consciousness. The activity of this function could be controlled in dead and dissected animals by touching a metal knife to the muscle fiber or by a spark being discharged on them. The electricity operated only as a stimulus of irritability, and it was irritability which was the one, true cause of the contractions.

Sources


    Related Research Articles

    <span class="mw-page-title-main">Alessandro Volta</span> Italian physicist and chemist (1745–1827)

    Alessandro Giuseppe Antonio Anastasio Volta was an Italian physicist and chemist who was a pioneer of electricity and power who is credited as the inventor of the electric battery and the discoverer of methane. He invented the voltaic pile in 1799, and reported the results of his experiments in 1800 in a two-part letter to the president of the Royal Society. With this invention Volta proved that electricity could be generated chemically and debunked the prevalent theory that electricity was generated solely by living beings. Volta's invention sparked a great amount of scientific excitement and led others to conduct similar experiments, which eventually led to the development of the field of electrochemistry.

    <span class="mw-page-title-main">Electromagnetism</span> Science of electricity and magnetism

    In physics, electromagnetism is an interaction that occurs between particles with electric charge via electromagnetic fields. The electromagnetic force is one of the four fundamental forces of nature. It is the dominant force in the interactions of atoms and molecules. Electromagnetism can be thought of as a combination of electrostatics and magnetism, two distinct but closely intertwined phenomena. Electromagnetic forces occur between any two charged particles, causing an attraction between particles with opposite charges and repulsion between particles with the same charge, while magnetism is an interaction that occurs exclusively between charged particles in relative motion. These two effects combine to create electromagnetic fields in the vicinity of charged particles, which can accelerate other charged particles via the Lorentz force. At high energy, the weak force and electromagnetic force are unified as a single electroweak force.

    <span class="mw-page-title-main">Electricity</span> Phenomena related to electric charge

    Electricity is the set of physical phenomena associated with the presence and motion of matter that has a property of electric charge. Electricity is related to magnetism, both being part of the phenomenon of electromagnetism, as described by Maxwell's equations. Various common phenomena are related to electricity, including lightning, static electricity, electric heating, electric discharges and many others.

    <span class="mw-page-title-main">Giovanni Aldini</span> Italian physician and physicist (1762–1834)

    Giovanni Aldini was an Italian physician and physicist born in Bologna. He was a brother of the statesman Count Antonio Aldini (1756–1826). He graduated in physics at University of Bologna in 1782.

    <span class="mw-page-title-main">Hydropower</span> Power generation via movement of water

    Hydropower, also known as water power, is the use of falling or fast-running water to produce electricity or to power machines. This is achieved by converting the gravitational potential or kinetic energy of a water source to produce power. Hydropower is a method of sustainable energy production. Hydropower is now used principally for hydroelectric power generation, and is also applied as one half of an energy storage system known as pumped-storage hydroelectricity. Hydropower is an attractive alternative to fossil fuels as it does not directly produce carbon dioxide or other atmospheric pollutants and it provides a relatively consistent source of power. Nonetheless, it has economic, sociological, and environmental downsides and requires a sufficiently energetic source of water, such as a river or elevated lake. International institutions such as the World Bank view hydropower as a low-carbon means for economic development.

    Timeline of electromagnetism and classical optics lists, within the history of electromagnetism, the associated theories, technology, and events.

    <span class="mw-page-title-main">Luigi Galvani</span> Italian physician, physicist, and philosopher

    Luigi Galvani was an Italian physician, physicist, biologist and philosopher, who studied animal electricity. In 1780, he discovered that the muscles of dead frogs' legs twitched when struck by an electrical spark. This was an early study of bioelectricity, following experiments by John Walsh and Hugh Williamson.

    <span class="mw-page-title-main">Irritable bowel syndrome</span> Functional gastrointestinal disorder

    Irritable bowel syndrome (IBS) is a "disorder of gut-brain interaction" characterized by a group of symptoms that commonly include abdominal pain, abdominal bloating and changes in the consistency of bowel movements. These symptoms may occur over a long time, sometimes for years. IBS can negatively affect quality of life and may result in missed school or work or reduced productivity at work. Disorders such as anxiety, major depression, and chronic fatigue syndrome are common among people with IBS.

    Electrification is the process of powering by electricity and, in many contexts, the introduction of such power by changing over from an earlier power source.

    <span class="mw-page-title-main">Leopoldo Marco Antonio Caldani</span> Italian anatomist and physiologist

    Leopoldo Marco Antonio Caldani (1725–1813) was an Italian anatomist and physiologist.

    Nuclear power plants operate in 32 countries and generate about a tenth of the world's electricity. Most are in Europe, North America, East Asia and South Asia. The United States is the largest producer of nuclear power, while France has the largest share of electricity generated by nuclear power, at about 70%. China has the fastest growing nuclear power programme with 16 new reactors under construction, followed by India, which has 8 under construction.

    <span class="mw-page-title-main">Felice Fontana</span> Italian physicist

    Abbé Gasparo Ferdinando Felice Fontana was an Italian polymath who contributed to experimental studies in physiology, toxicology, and physics. As a physicist he discovered the water gas shift reaction in 1780. He investigated the human eye and has also been credited with discovering the nucleolus of a cell. His work on the venom of vipers was among the earliest experimental toxicological studies. He served as a court physicist for Peter Leopold, Duke of Tuscany and taught at the University of Pisa. He was involved in the establishment of the La Specola museum in Florence.

    <span class="mw-page-title-main">Hera Group</span>

    Hera S.p.A is a multiutility company based in Bologna, Italy. Hera operates in the distribution of gas, water, energy, and waste disposal in the provinces of Bologna, Ferrara, Forlì-Cesena, Modena, Ravenna, Rimini, Pesaro and Urbino, and in some municipalities of Florence and Ancona.

    <span class="mw-page-title-main">Energy in Italy</span> Overview of the production, consumption, import and export of energy and electricity in Italy

    Energy in Italy comes mostly from fossil fuels. Among the most used resources are petroleum, natural gas, coal and renewables. Italy has few energy resources, and most supplies are imported.

    Italy's total electricity consumption was 302.75 terawatt-hour (TWh) in 2020, of which 270.55 TWh (89.3%) was produced domestically and the remaining 10.7% was imported.

    The frog galvanoscope was a sensitive electrical instrument used to detect voltage in the late 18th and 19th centuries. It consists of a skinned frog's leg with electrical connections to a nerve. The instrument was invented by Luigi Galvani and improved by Carlo Matteucci.

    <span class="mw-page-title-main">Renewable energy in Italy</span>

    Renewable energy has developed rapidly in Italy over the past decade and provided the country a means of diversifying from its historical dependency on imported fuels. Solar power accounted for around 8% of the total electric production in the country in 2014, making Italy the country with the highest contribution from solar energy in the world that year. Rapid growth in the deployment of solar, wind and bio energy in recent years lead to Italy producing over 40% of its electricity from renewable sources in 2014.

    <span class="mw-page-title-main">Franklin's electrostatic machine</span> Experimental device

    Franklin's electrostatic machine is a high-voltage static electricity-generating device used by Benjamin Franklin in the mid-18th century for research into electrical phenomena. Its key components are a glass globe which turned on an axis via a crank, a cloth pad in contact with the spinning globe, a set of metal needles to conduct away the charge developed on the globe by its friction with the pad, and a Leyden jar – a high-voltage capacitor – to accumulate the charge. Franklin's experiments with the machine eventually led to new theories about electricity and inventing the lightning rod.

    <span class="mw-page-title-main">Olorinab</span> Chemical compound

    Olorinab (APD371) is a drug being developed by Arena Pharmaceuticals for the treatment of gastrointestinal pain associated with Crohn's disease and irritable bowel syndrome. It acts as a potent and selective cannabinoid CB2 receptor agonist and is claimed to be orally active and peripherally selective. Initial Phase IIa exploratory clinical trials have been successful in patients with quiescent Crohn's disease. Arena initiated the Phase IIb Captivate trial in late July 2019 in patients with irritable bowel syndrome related pain, in constipation and diarrhea predominant sub-types. The Phase IIb trial is expected to enroll 240 participants between the ages of 18 and 70.Three doses of 10 mg, 25 mg, and 50 mg are being tested against Placebo in a 3:4 prescription ratio with a Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) masking layout.

    <span class="mw-page-title-main">RQ-00202730</span> Chemical structure

    RQ-00202730 is a benzimidazole derived drug that acts as a potent and highly selective agonist for the CB2 cannabinoid receptor, with a Ki value of 19nM at CB2 and more than 4000x selectivity over CB1, though it also shows some activity as an antagonist of the unrelated 5-HT2B serotonin receptor. It has analgesic and antiinflammatory effects in animal studies, and was developed for the treatment of irritable bowel syndrome, but was ultimately discontinued from development following disappointing results in Phase II clinical trials.