Moffett's solution

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Moffett's solution is a mixture of adrenaline, sodium bicarbonate and cocaine [1] [2] that is used to provide topical analgesia and vasoconstriction during ear, nose, and throat surgery, especially for operations on the nose.

The solution is named after Arthur James Moffett (1904–1995) of the Royal Army Medical Corps who first described the solution in 1941. [3] [4]

References

  1. "ENT".
  2. Benjamin, E; Wong, DK; Choa, D (December 2004). "'Moffett's' solution: a review of the evidence and scientific basis for the topical preparation of the nose". Clinical Otolaryngology and Allied Sciences. 29 (6): 582–7. doi: 10.1111/j.1365-2273.2004.00894.x . PMID   15533141.
  3. Moffett, AJ (1941). "Postural Instillation: A Method of Inducing Local Anæsthesia in the Nose". The Journal of Laryngology & Otology. 56 (12): 429–436. doi:10.1017/S0022215100006782.
  4. "Moffett, Arthur James (1904–1995)". Plarr's Lives of the Fellows. Royal College of Surgeons of England. Retrieved 18 January 2026.