Megastudy

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A megastudy or mega-study is a research study in which a large number of different treatments or interventions are tested at the same time, on the same sample or similar samples, using a common outcome measure, and using the same experimental protocol. [1] [2] [3]

Contents

This research design ensures the outcomes across interventions are comparable. Additionally, due to generous inclusion of various interventions in the study, megastudies may be less prone to publication bias, where the interventions expected to be effective are more likely to be studied and the interventions found to be ineffective are underreported due to the file-drawer problem. [4]

Megastudy examples

Many-lab studies

The megastudy technique can be combined with the many-labs approach, so that teams of researchers from across the planet conduct the same experiment locally. [3] [7]

Megastudy criticisms

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References

  1. 1 2 Milkman, K.L., Gromet, D., Ho, H. et al. Megastudies improve the impact of applied behavioural science. Nature 600, 478–483 (2021). https://doi.org/10.1038/s41586-021-04128-4
  2. Angela L Duckworth, Katherine L Milkman, A guide to megastudies, PNAS Nexus, Volume 1, Issue 5, November 2022, https://doi.org/10.1093/pnasnexus/pgac214
  3. 1 2 3 Doell, K.C. Megastudies to test the efficacy of behavioural interventions. Nat Rev Psychol 2, 263 (2023). https://doi.org/10.1038/s44159-023-00174-z
  4. 1 2 3 Tkachenko, Y., Jedidi, K. A megastudy on the predictability of personal information from facial images: Disentangling demographic and non-demographic signals. Sci Rep 13, 21073 (2023). https://doi.org/10.1038/s41598-023-42054-9
  5. Milkman, Katherine L., et al. "A 680,000-person megastudy of nudges to encourage vaccination in pharmacies." Proceedings of the National Academy of Sciences 119.6 (2022): e2115126119. https://doi.org/10.1073/pnas.2115126119
  6. Voelkel, Jan G., et al. "Megastudy identifying successful interventions to strengthen Americans’ democratic attitudes." Northwestern University: Evanston, IL, USA (2022). https://www.ipr.northwestern.edu/documents/working-papers/2022/wp-22-38.pdf
  7. Pavlov, Yuri G.; Adamian, Nika; Appelhoff, Stefan; Arvaneh, Mahnaz; Benwell, Christopher S. Y.; Beste, Christian; Bland, Amy R.; Bradford, Daniel E.; Bublatzky, Florian; Busch, Niko A.; Clayson, Peter E.; Cruse, Damian; Czeszumski, Artur; Dreber, Anna; Dumas, Guillaume (2021-11-01). "#EEGManyLabs: Investigating the replicability of influential EEG experiments". Cortex. 144: 213–229. doi:10.1016/j.cortex.2021.03.013. ISSN   0010-9452.
  8. 1 2 Collins J (2022-05-27). "Megastudy scepticism". jasoncollins.blog. Retrieved 2023-12-13.