Randolph Martin Nesse | |
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| Born | July 10, 1948 |
| Education | Carleton College University of Michigan |
| Known for | evolutionary medicine evolutionary psychiatry |
| Scientific career | |
| Institutions | University of Michigan Arizona State University |
| Doctoral students | Matthew C. Keller |
| Website | www |
Randolph Martin Nesse (born July 10, 1948) [1] is an American physician, scientist and author who is notable for his role as a founder of the field of evolutionary medicine and evolutionary psychiatry. [2] [3]
Nesse studied at Carleton College from 1966 to 1970. He went on to receive his M.D. at the University of Michigan Medical School in 1974 and carried out his medical residency at the same place. Nesse became an instructor in psychiatry at the University of Michigan in 1977 and became an assistant professor there in psychiatry in 1979. He became associate professor in psychiatry in 1985 and professor in psychiatry in 1993 at University of Michigan, where he was also a professor of psychology since 2001. Nesse became professor emeritus at Michigan at the end of 2013. [4]
Since 2014, Nesse became professor of life sciences and ASU Foundation Professor at Arizona State University, where he became the Founding Director of the Center for Evolution and Medicine. He was previously a professor of psychiatry, professor of psychology and research professor at the University of Michigan where he led the Evolution and Human Adaptation Program and helped to establish one of the world's first anxiety disorders clinics and conducted research on neuroendocrine responses to fear. [5]
Nesse's research on the evolution of aging led to a long collaboration with the evolutionary biologist George C. Williams. [6] Their co-authored book, Why We Get Sick: The New Science of Darwinian Medicine, inspired fast growth of the field of evolutionary medicine. [7] His subsequent research has focused on how natural selection shapes mechanisms that regulate pain, fever, anxiety, low mood, and why emotional disorders are so common. He also has written extensively about the evolutionary origins of moral emotions, and strategies for establishing evolutionary biology as a basic science for medicine. Good Reasons for Bad Feelings: Insights from the Frontier of Evolutionary Psychiatry applies the principles of evolutionary medicine to mental disorders. [8]
Nesse was the initial organizer and second president of the Human Behavior and Evolution Society, and is currently the president of the International Society for Evolution, Medicine & Public Health. He is a Distinguished Life Fellow of the American Psychiatric Association, a Fellow of the Association for Psychological Science, and an elected Fellow of the AAAS.
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Arachnophobia is a specific phobia brought about by the irrational fear of spiders and other arachnids such as scorpions and ticks. The word Arachnophobia comes from the Greek words arachne and phobia.
A mental disorder is an impairment of the mind disrupting normal thinking, feeling, mood, behavior, or social interactions, and accompanied by significant distress or dysfunction. The causes of mental disorders are very complex and vary depending on the particular disorder and the individual. Although the causes of most mental disorders are not fully understood, researchers have identified a variety of biological, psychological, and environmental factors that can contribute to the development or progression of mental disorders. Most mental disorders result in a combination of several different factors rather than just a single factor.
A mood disorder, also known as an affective disorder, is any of a group of conditions of mental and behavioral disorder where a disturbance in the person's mood is the main underlying feature. The classification is in the Diagnostic and Statistical Manual of Mental Disorders (DSM) and International Classification of Diseases (ICD).
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by executive dysfunction occasioning symptoms of inattention, hyperactivity, impulsivity and emotional dysregulation that are excessive and pervasive, impairing in multiple contexts, and otherwise age-inappropriate.
George Christopher Williams was an American evolutionary biologist.
Ophidiophobia is a specific phobia of snakes. It is sometimes called by the more general term herpetophobia, fear of reptiles. The word comes from the Greek words "ophis" (ὄφις), snake, and "phobia" (φοβία) meaning fear.
Evolutionary medicine or Darwinian medicine is the application of modern evolutionary theory to understanding health and disease. Modern biomedical research and practice have focused on the molecular and physiological mechanisms underlying health and disease, while evolutionary medicine focuses on the question of why evolution has shaped these mechanisms in ways that may leave us susceptible to disease. The evolutionary approach has driven important advances in the understanding of cancer, autoimmune disease, and anatomy. Medical schools have been slower to integrate evolutionary approaches because of limitations on what can be added to existing medical curricula. The International Society for Evolution, Medicine and Public Health coordinates efforts to develop the field. It owns the Oxford University Press journal Evolution, Medicine and Public Health and The Evolution and Medicine Review.
The Human Behavior and Evolution Society (HBES) is an interdisciplinary, international society of researchers, primarily from the social and biological sciences, who use modern evolutionary theory to help to discover human nature — including evolved emotional, cognitive and sexual adaptations. It was founded on October 29, 1988 at the University of Michigan.
Genetic assimilation is a process described by Conrad H. Waddington by which a phenotype originally produced in response to an environmental condition, such as exposure to a teratogen, later becomes genetically encoded via artificial selection or natural selection. Despite superficial appearances, this does not require the (Lamarckian) inheritance of acquired characters, although epigenetic inheritance could potentially influence the result. Waddington stated that genetic assimilation overcomes the barrier to selection imposed by what he called canalization of developmental pathways; he supposed that the organism's genetics evolved to ensure that development proceeded in a certain way regardless of normal environmental variations.
Evolutionary physiology is the study of the biological evolution of physiological structures and processes; that is, the manner in which the functional characteristics of individuals in a population of organisms have responded to natural selection across multiple generations during the history of the population. It is a sub-discipline of both physiology and evolutionary biology. Practitioners in the field come from a variety of backgrounds, including physiology, evolutionary biology, ecology, and genetics.
Evolutionary approaches to depression are attempts by evolutionary psychologists to use the theory of evolution to shed light on the problem of mood disorders within the perspective of evolutionary psychiatry. Depression is generally thought of as dysfunction or a mental disorder, but its prevalence does not increase with age the way dementia and other organic dysfunction commonly does. Some researchers have surmised that the disorder may have evolutionary roots, in the same way that others suggest evolutionary contributions to schizophrenia, sickle cell anemia, psychopathy and other disorders. Psychology and psychiatry have not generally embraced evolutionary explanations for behaviors, and the proposed explanations for the evolution of depression remain controversial.
Accident-proneness is the idea that some people have a greater predisposition than others to experience accidents, such as car crashes and industrial injuries. It may be used as a reason to deny any insurance on such individuals.
The evolutionary psychology of religion is the study of religious belief using evolutionary psychology principles. It is one approach to the psychology of religion. As with all other organs and organ functions, the brain's functional structure is argued to have a genetic basis, and is therefore subject to the effects of natural selection and evolution. Evolutionary psychologists seek to understand cognitive processes, religion in this case, by understanding the survival and reproductive functions they might serve.
Gamma-aminobutyric acid receptor subunit alpha-6 is a protein that in humans is encoded by the GABRA6 gene.
Michael Terrence McGuire was an American psychiatrist who made contributions to the theory of psychoanalysis, biological psychiatry, evolutionary biology, sociobiology and the theory and practice of psychiatry.
The imprinted brain hypothesis is an unsubstantiated hypothesis in evolutionary psychology regarding the causes of autism spectrum and schizophrenia spectrum disorders, first presented by Bernard Crespi and Christopher Badcock in 2008. It claims that certain autistic and schizotypal traits are opposites, and that this implies the etiology of the two conditions must be at odds.
The fear of falling (FOF), also referred to as basophobia, is a natural fear and is typical of most humans and mammals, in varying degrees of extremity. It differs from acrophobia, although the two fears are closely related. The fear of falling encompasses the anxieties accompanying the sensation and the possibly dangerous effects of falling, as opposed to the heights themselves. Those who have little fear of falling may be said to have a head for heights. Basophobia is sometimes associated with astasia-abasia, the fear of walking/standing erect.
Evolutionary psychiatry, also known as Darwinian psychiatry, is a theoretical approach to psychiatry that aims to explain psychiatric disorders in evolutionary terms. As a branch of the field of evolutionary medicine, it is distinct from the medical practice of psychiatry in its emphasis on providing scientific explanations rather than treatments for mental disorder. This often concerns questions of ultimate causation. For example, psychiatric genetics may discover genes associated with mental disorders, but evolutionary psychiatry asks why those genes persist in the population. Other core questions in evolutionary psychiatry are why heritable mental disorders are so common how to distinguish mental function and dysfunction, and whether certain forms of suffering conveyed an adaptive advantage. Disorders commonly considered are depression, anxiety, schizophrenia, autism, eating disorders, and others. Key explanatory concepts are of evolutionary mismatch and the fact that evolution is guided by reproductive success rather than health or wellbeing. Rather than providing an alternative account of the cause of mental disorder, evolutionary psychiatry seeks to integrate findings from traditional schools of psychology and psychiatry such as social psychology, behaviourism, biological psychiatry and psychoanalysis into a holistic account related to evolutionary biology. In this sense, it aims to meet the criteria of a Kuhnian paradigm shift.
Charles L. Raison is an American psychiatrist and professor of psychiatry at the University of Wisconsin-Madison School of Medicine and Public Health as well as the Mary Sue and Mike Shannon Chair for Healthy Minds, Children & Families and Professor with the School of Human Ecology in Madison, Wisconsin.
Social selection is a term used with varying meanings in biology.
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