Sulfur dioxygenase

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Sulfur dioxygenase
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EC no. 1.13.11.18
CAS no. 37256-58-9
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Sulfur dioxygenase (EC 1.13.11.18, sulfur oxygenase, sulfur:oxygen oxidoreductase) is an enzyme with systematic name S-sulfanylglutathione:oxygen oxidoreductase. [1] [2] This enzyme catalyses the following chemical reaction

sulfur + O2 + H2O sulfite + 2 H+ (overall reaction)
(1a) glutathione + sulfur S-sulfanylglutathione (spontaneous reaction)
(1b) S-sulfanylglutathione + O2 + H2O glutathione + sulfite + 2 H+

This enzyme contains iron.

In humans, sulfur dioxygenase is needed to detoxify sulfide. [3]

Related Research Articles

In chemistry, disproportionation, sometimes called dismutation, is a redox reaction in which one compound of intermediate oxidation state converts to two compounds, one of higher and one of lower oxidation states. The reverse of disproportionation, such as when a compound in an intermediate oxidation state is formed from precursors of lower and higher oxidation states, is called comproportionation, also known as synproportionation.

<span class="mw-page-title-main">Sulfite dehydrogenase</span>

In enzymology, a sulfite dehydrogenase (EC 1.8.2.1) is an enzyme that catalyzes the chemical reaction

In enzymology, a 4-sulfobenzoate 3,4-dioxygenase (EC 1.14.12.8) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Benzene 1,2-dioxygenase</span> Class of enzymes

In enzymology, a benzene 1,2-dioxygenase is an enzyme that catalyzes the chemical reaction

In enzymology, a benzoate 1,2-dioxygenase (EC 1.14.12.10) is an enzyme that catalyzes the chemical reaction

In enzymology, a choline monooxygenase (EC 1.14.15.7) is an enzyme that catalyzes the chemical reaction

In enzymology, a leucocyanidin oxygenase (EC 1.14.11.19) is an enzyme that catalyzes the chemical reaction

In enzymology, a steroid 11beta-monooxygenase (EC 1.14.15.4) is an enzyme that catalyzes the chemical reaction

In enzymology, a taurine dioxygenase (EC 1.14.11.17) is an enzyme that catalyzes the chemical reaction.

In enzymology, a cysteamine dioxygenase (EC 1.13.11.19) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Sulfur oxygenase/reductase</span>

In enzymology, a sulfur oxygenase/reductase (EC 1.13.11.55) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">ETHE1</span> Protein-coding gene in the species Homo sapiens

Protein ETHE1, mitochondrial, also known as "ethylmalonic encephalopathy 1 protein" and "per sulfide dioxygenase", is a protein that in humans is encoded by the ETHE1 gene located on chromosome 19.

2-oxoglutarate dioxygenase (ethylene-forming) (EC 1.13.12.19, ethylene-forming enzyme, EFE) is an enzyme with systematic name 2-oxoglutarate:oxygen oxidoreductase (decarboxylating, ethylene-forming). This enzyme catalyses the following chemical reaction

Zeaxanthin epoxidase (EC 1.14.13.90, Zea-epoxidase) is an enzyme with systematic name zeaxanthin,NAD(P)H:oxygen oxidoreductase. This enzyme catalyses the following chemical reaction

Methanesulfonate monooxygenase (EC 1.14.13.111, mesylate monooxygenase, mesylate,reduced-FMN:oxygen oxidoreductase, MsmABCD, methanesulfonic acid monooxygenase, MSA monooxygenase, MSAMO) is an enzyme with systematic name methanesulfonate,NADH:oxygen oxidoreductase. This enzyme catalyses the following chemical reaction

Isoleucine N-monooxygenase (EC 1.14.13.117, CYP79D3, CYP79D4) is an enzyme with systematic name L-isoleucine,NADPH:oxygen oxidoreductase (N-hydroxylating). This enzyme catalyses the following chemical reaction

Valine N-monooxygenase (EC 1.14.13.118, CYP79D1, CYP79D2) is an enzyme with systematic name L-valine,NADPH:oxygen oxidoreductase (N-hydroxylating). This enzyme catalyses the following chemical reaction

Pentalenene oxygenase (EC 1.14.15.32, Formerly EC 1.14.13.133, PtlI) is an enzyme with systematic name pentalenene,NADPH:oxygen 13-oxidoreductase. This enzyme catalyses the following chemical reaction

Spheroidene monooxygenase (EC 1.14.15.9, CrtA, acyclic carotenoid 2-ketolase, spirilloxantin monooxygenase, 2-oxo-spirilloxanthin monooxygenase) is an enzyme with systematic name spheroidene, reduced-ferredoxin:oxygen oxidoreductase (spheroiden-2-one-forming). This enzyme catalyses the following chemical reaction

2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase (EC 1.14.20.2, BX6 (gene), DIBOA-Glc dioxygenase) is an enzyme with systematic name (2R)-4-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside:oxygen oxidoreductase (7-hydroxylating). This enzyme catalyses the following chemical reaction

References

  1. ↑ Suzuki I, Silver M (July 1966). "The initial product and properties of the sulfur-oxidizing enzyme of thiobacilli". Biochimica et Biophysica Acta (BBA) - Enzymology and Biological Oxidation. 122 (1): 22–33. doi:10.1016/0926-6593(66)90088-9. PMID   5968172.
  2. ↑ Rohwerder T, Sand W (July 2003). "The sulfane sulfur of persulfides is the actual substrate of the sulfur-oxidizing enzymes from Acidithiobacillus and Acidiphilium spp". Microbiology. 149 (Pt 7): 1699–710. doi: 10.1099/mic.0.26212-0 . PMID   12855721.
  3. ↑ Viscomi C, Burlina AB, Dweikat I, Savoiardo M, Lamperti C, Hildebrandt T, Tiranti V, Zeviani M (August 2010). "Combined treatment with oral metronidazole and N-acetylcysteine is effective in ethylmalonic encephalopathy". Nature Medicine. 16 (8): 869–71. doi:10.1038/nm.2188. hdl: 11577/3321433 . PMID   20657580.
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